Results 81 to 90 of about 126,895 (241)

Exosome‐mimetic vesicle‐encapsulated multi‐responsive antibacterial hydrogel core‐shell microneedle patch promotes scarless healing of infected wounds

BMEMat, EarlyView.
The core‐shell microneedle patch VP@FNV‐CuO2‐MN was fabricated by encapsulating n‐CuO2 in a moderately crosslinked PVA/CMCS/Borax4 hydrogel shell and VP‐loaded fibroblast membrane nanovesicles (VP@FNV) in a highly crosslinked PVA/CMCS/Borax6 hydrogel core. Upon application to an infected wound, the acidic microenvironment triggers Fenton‐like reactions
Ziwei Jiang, Huihui Zhang, Lianglong Chen, Zhangfeifan Yang, Sai Cao, Yufang He, Xiaoyang Liu, Siew Yee Wong, Xu Li, Hai Zhou, Ziyan Li, Zijun Zheng, Lei Yang   +12 more
wiley   +1 more source

MRSA-specific memory CD4 T cells.

, 2016
Flow cytometry analysis of MRSA-specific memory (CD27+CD45RO+ or CD27-) CD4 T-cell responses in HIV-infected or HIV-uninfected participants with MRSA SSTI, colonization or neither.
Brian K. Agan (254830), Anoma Somasunderam (240695), J. Katherina Timmer (3173058), David R. Morcock (517271), Annelys Roque (121093), Daniel C. Douek (121117), Nancy F. Crum-Cianflone (254822), Jacob D. Estes (194109), Amy C. Weintrob (254826), Claire DeLeage (3173055), Netanya S. Utay (847230)   +10 more
core   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

Engineering programmable peptide hydrogels for chronic refractory wounds: A mechanism‐driven framework

BMEMat, EarlyView.
To break the self‐perpetuating pathology of chronic wounds, we propose a mechanism‐driven engineering framework for peptide‐based hydrogels. This review elucidates a hierarchical strategy—from molecular design to intelligent, multi‐functional systems—that enables these programmable biomaterials to dynamically intervene in key pathological loops and ...
Xiaoyu Lv, Xinyi Chao, Jiamin Zhang, Jianfeng Liu   +3 more
wiley   +1 more source

Antimicrobial Peptides and Peptidomimetics in Foods – A Synthetic Foray

ChemFoodChem, EarlyView.
This Review discusses AMPs in foods and their syntheses. It espouses facile methods to make them accessible and suggests their utility in the mitigation and eradication of the burgeoning maladies of antimicrobial and multidrug resistance (AMR and MDR).
Josephat U. Izunobi, Adejoke D. Osinubi, Abosede A. Badeji   +2 more
wiley   +1 more source

Induction heating combined with antibiotics or SAAP-148 effectively reduces biofilm-embedded Staphylococcus aureus on a fracture-related implant mimic

Bone & Joint Research
Aims: Fracture-related infections and the associated treatment failure burden our society and healthcare system significantly. As an alternative approach, we investigated the effect of non-contact induction heating (NCIH) against Staphylococcus aureus ...
Marielle Verheul, Anne A. Wagenmakers, Rob G. H. H. Nelissen, Peter H. Nibbering, Bart G. Pijls   +4 more
doaj   +1 more source

All‐in‐One Intelligent Hemostatic Sponge: Rapid Hemostasis for Non‐Compressive Wounds With Synergetic Enhanced Antibacterial Efficacy and Self‐Reporting Biodegradation

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Clinicians often concurrently tackle critical challenges including emergency hemorrhage, secondary infection, and the elusive tracking of biodegradation of conventional hemostatic agents for complex wounds. Here, we report an intelligent hemostatic sponge (spCS@AIE) by incorporating aggregation‐induced emission (AIE) nanoparticles with short‐wave ...
Zhicheng Liu, Yan Zhang, Mengmeng Wang, Ye Li, Heng Sun, Lanqiong Zhang, Xin Bai, Haicheng Wei, Zhi Wang, Hao Guan, Yanzi Xu, Dongfeng Dang, Lingjie Meng   +12 more
wiley   +1 more source

A Parametric Computational Framework for Modeling and Seismic Design of Post‐Tensioned Mass Timber Rocking Walls

Earthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT Post‐tensioned cross‐laminated timber (PT‐CLT) rocking walls offer a compelling seismic system combining self‐centering behavior with energy dissipation. However, progress in their performance assessment and design has been limited by the lack of a comprehensive parametric modeling tool, as exists for steel or reinforced concrete systems. This
Ghasem B. Shargh, André R. Barbosa, John W. van de Lindt, Nathan C. Brown   +3 more
wiley   +1 more source

Thirteen years of environmental surveillance of ESKAPE organisms and Escherichia coli in an equine hospital: Informing infection control

Equine Veterinary Journal, EarlyView.
Abstract Background Bacteria from the ESKAPE group (i.e., Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa and Enterobacter species) and Escherichia coli are frequently multidrug‐resistant and can be associated with healthcare‐associated infections, an increasing concern for veterinary ...
April Lawson, Gina Pinchbeck, Flavia Zendri, Cajsa Isgren, Jane Devaney, Fernando Malalana, Dorina Timofte   +6 more
wiley   +1 more source

Typing early Australian healthcare-associated MRSA : confirmation of major clones and emergence of ST1-MRSA-IV and novel ST2249-MRSA-III

, 2013
Aims: To investigate the evolutionary origins of Australian healthcare-associated (HCA) methicillin-resistant Staphylococcus aureus (MRSA) strains from a panel of historical isolates typed using current genotyping techniques.
Lancashire, John F, Lancashire, John F., Huygens, Flavia, Nimmo, Graeme R, Nimmo, Graeme R., Jones, Anna, Bergh, Haakon   +6 more
core   +1 more source