Results 101 to 110 of about 189,379 (305)

Aptamer Engineering: Strategies for Discovering Functional Nucleic Acids for Next‐Generation Diagnostics and Biosensing

Advanced Science, EarlyView.
The advent of aptamers has highlighted their potential as alternatives to antibodies, overcoming limitations of structural instability and production cost. However, conventional approaches such as SELEX remain slow and labor‐intensive. This review examines recent advances in aptamer engineering, emphasizing in vitro and AI‐driven in silico strategies ...
John V. L. Nguyen, Ahlem Meziadi, Cyrill Brunner, Maureen McKeague, Lidija Malic, Maryam Tabrizian   +5 more
wiley   +1 more source

Ontological representation of CDC Active Bacterial Core Surveillance Case Reports [PDF]

, 2014
The Center for Disease Control and Prevention’s Active Bacterial Core Surveillance (CDC ABCs) Program is a collaborative effort betweeen the CDC, state health departments, laboratories, and universities to track invasive bacterial pathogens of particular
Cowell, Lindsay G., Goldfain, Albert, Smith, Barry   +2 more
core  

RADA16 and SAAP148 Peptide‐Modified Collagen Self‐Assembled Hydrogels for Accelerated Healing of Infected Wounds

Advanced Science, EarlyView.
Collagen type I (Col I) is integrated with self‐assembling peptide RADA16 and loaded with anti‐bacterial peptide SAAP148 to develop a self‐assembled nano‐microstructure hydrogel (Col I‐RADA16‐SAAP148, CRS) without chemical cross‐linkers. CRS exhibits excellent mechanical properties, sustained SAAP148 release to inhibit bacterial infection, macrophage ...
Qian Liu, Jiawei Wu, Ho‐Pan Bei, Yufei Chen, Yifan Zhang, Xueliang Peng, Fulin Chen, Xin Zhao, Zhuoyue Chen   +8 more
wiley   +1 more source

Comparing Prophylactic Administration of Sulbactam/Ampicillin Versus Cefmetazole for Prevention of Perineal Wound Infection Following Abdominoperineal Resection for Rectal Cancer: A Multicenter Randomized Controlled Trial

Annals of Gastroenterological Surgery, EarlyView.
This prospective randomized trial demonstrated that a 4‐day regimen of sulbactam/ampicillin significantly reduced the incidence of perineal wound infection (PWI) following abdominoperineal resection compared to a 1‐day cefmetazole regimen. This simple approach to antibiotic selection may be beneficial for preventing PWI.
Akitoshi Nankaku, Shunsuke Kasai, Akio Shiomi, Taiki Masuda, Hiroyuki Hazama, Noriko Iwata, Shunichiro Kato, Shinichi Yamauchi, Hiroyuki Sato, Akihiro Hirakawa, Hiroyasu Kagawa, Masanori Tokunaga, Yusuke Kinugasa   +12 more
wiley   +1 more source

Bacterial DNA‐Targeting AIE Photosensitizer for Efficient Eradication of Intracellular Bacteria and Biofilm‐Associated Infections

Aggregate, EarlyView.
A bacterial DNA‐targeted PS TPE‐CN for the precise treatment of MRSA‐associated infections has been developed. Through synergistic PDT effect, TPE‐CN damages bacterial DNA and membrane, resulting in effective elimination of planktonic bacteria, biofilm, and intracellular bacteria.
Yonghui Lv, Minyang Zhao, Qiaowen Lin, Zhiwen Xu, Qingqing Bai, Dan Ding, Duo Mao, Kang‐Nan Wang   +7 more
wiley   +1 more source

Green Synthesis of Silver Nanoparticles: A Review of Polymer and Antimicrobial Drug Combinations for Enhanced Antimicrobial Applications

Advanced NanoBiomed Research, EarlyView.
Silver nanoparticles (AgNPs) synthesized using eco‐friendly green synthesis approaches exhibit remarkable antimicrobial activity and enhanced drug delivery potential. Polymer‐AgNPs conjugates further improve drug stability and targeted delivery, offering a multifunctional platform for biomedical applications.
Mukil Madhusudanan, Jian Zhang, Santosh Pandit, Priyanka Singh, Geum‐Jae Jeong, Fazlurrahman Khan, Ivan Mijakovic   +6 more
wiley   +1 more source

Targeting Antibacterial Effect and Promoting of Skin Wound Healing After Infected with Methicillin-Resistant Staphylococcus aureus for the Novel Polyvinyl Alcohol Nanoparticles

International Journal of Nanomedicine, 2021
Dengyan Wu,1 Dong Wei,2 Maotao Du,1 Song Ming,1 Qian Ding,1 Ranjing Tan1 1Department of Dermatology, Second affiliated Hospital, Chongqing Medical University, Chongqing, 400010, People’s Republic of China; 2Plastic Surgery, Pengshui County People ...
Wu D, Wei D, Du M, Ming S, Ding Q, Tan R
doaj  

Phenotypic and Genotypic Characteristics of Methicillin-Resistant Staphylococcus aureus (MRSA) Related to Persistent Endovascular Infection. [PDF]

, 2019
Persistent methicillin-resistant Staphylococcus aureus (MRSA) bacteremia (PB) represents an important subset of S. aureus infection and correlates with poor clinical outcomes.
Bayer, Arnold S, Li, Liang, Xiong, Yan Q, Yeaman, Michael R   +3 more
core   +1 more source

Molecular analysis of methicillin-resistant Staphylococcus aureus isolates from four teaching hospitals in Iran: The emergence of novel MRSA clones [PDF]

, 2020
Farzaneh Firoozeh, Mitra Omidi, Mahmood Saffari, Hossein Sedaghat, Mohammad Zibaei   +4 more
openalex   +1 more source

A Combined Phenotypic-Genotypic Predictive Algorithm for In Vitro Detection of Bicarbonate: β-Lactam Sensitization among Methicillin-Resistant Staphylococcus aureus (MRSA) [PDF]

, 2021
Selvi C. Ersoy, Warren E. Rose, Robin Patel, Richard A. Proctor, Henry F. Chambers, Ewan M. Harrison, Youngju Pak, Arnold S. Bayer   +7 more
openalex   +1 more source