Results 1 to 10 of about 345,094 (162)
Journal of Extracellular Vesicles, 2019 Small extracellular vesicles (sEVs) from mesenchymal stromal/stem cells (MSCs) are transiting rapidly towards clinical applications. However, discrepancies and controversies about the biology, functions, and potency of MSC-sEVs have arisen due to several
Kenneth W Witwer +2 more
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DNMT1 is a negative regulator of osteogenesis
Biology Open, 2022 The role and underlying mechanisms of DNA methylation in osteogenesis/chondrogenesis remain poorly understood. We here reveal DNA methyltransferase 1 (DNMT1), which is responsible for copying DNA methylation onto the newly synthesized DNA strand after ...
Chen Tao +10 more
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Study of the Role of Heparin in Regulation of the Morphofunctional Properties of MSC in Vitro
Разработка и регистрация лекарственных средств, 2022 Introduction. Artificial materials used in regenerative medicine induce a balanced inflammatory response after implantation, which is an important step for effective regeneration of damaged bone tissue.
I. K. Norkin +8 more
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The role of MSCs and CAR-MSCs in cellular immunotherapy
Cell Communication and Signaling, 2023 AbstractChimeric antigen receptors (CARs) are widely used by T cells (CAR-T cells), natural killer cells dendritic cells and macrophages, and they are of great importance in cellular immunotherapy. However, the use of CAR-related products faces several challenges, including the poor persistence of cells carrying CARs, cell dysfunction or exhaustion ...
Lun Yan, Jing Li, Cheng Zhang
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Bounded MSC Communication [PDF]
Information and Computation, 2002 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Markus Lohrey, Anca Muscholl
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MSCs: science and trials [PDF]
Nature Medicine, 2013 Although the field of regenerative medicine is rife with unsubstantiated claims of benefit and is often biased by strong commercial interests, it is important that the legitimate scientific enterprise does not allow this noise to overshadow meaningful advances in the field.
Fibbe, W.E., Dazzi, F., LeBlanc, K.
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Immunomodulation of MSCs and MSC-Derived Extracellular Vesicles in Osteoarthritis [PDF]
Frontiers in Bioengineering and Biotechnology, 2020 Osteoarthritis (OA) has become recognized as a low-grade inflammatory state. Inflammatory infiltration of the synovium by macrophages, T cells, B cells, and other immune cells is often observed in OA patients and plays a key role in the pathogenesis of OA.
Xige Zhao +6 more
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Initial Description of Pilotage and Tug Services in the Context of e-Navigation
Journal of Marine Science and Engineering, 2020 The International Maritime Organization (IMO)’s Maritime Safety Committee (MSC), at its 101st session (5 to 14 June 2019), adopted Resolution MSC.467(101) on the guidance on the definition and harmonization of the format and structure of maritime ...
Adam Weintrit
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Frontiers in Cell and Developmental Biology, 2021 Mesenchymal stromal cells (MSCs) currently constitute the most frequently used cell type in advanced therapies with different purposes, most of which are related with inflammatory processes.
David García-Bernal +32 more
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POSSIBILITIES OF CURRENT CELLULAR TECHNOLOGIES FOR ARTICULAR CARTILAGE REPAIR (ANALYTICAL REVIEW)
Travmatologiâ i Ortopediâ Rossii, 2016 Despite a wide variety of surgical procedures utilized in clinical practice for treatment of articular cartilage lesions, the search for other options of articular reconstruction remains a relevant and open issue at the current stage of medicine and ...
M. S. Bozhokin +2 more
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