Results 171 to 180 of about 136,502 (304)

Initial treatment strategies and outcomes across haemodynamic thresholds and risk stratification in incident systemic sclerosis–associated pulmonary arterial hypertension: a EUSTAR analysis

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Real‐world initial treatment strategies in SSc‐PAH remain incompletely described. We aimed to characterise these strategies across haemodynamic thresholds and risk strata and evaluate outcome associations. Methods We analysed treatment‐naïve SSc‐PAH patients in EUSTAR (2000–2021) fulfilling the 2022 haemodynamic definition.
Hilde Jenssen Bjørkekjær   +30 more
wiley   +1 more source

Effective arterial elastance relates more closely to pulsatile than resistive indices during routine haemodynamic assessment of inoperable chronic thromboembolic pulmonary hypertension. [PDF]

open access: yesERJ Open Res
Chemla D   +11 more
europepmc   +1 more source

Biochemical Studies and Production Optimization of β‐Glucosidase From Microcystis aeruginosa CACIAM 03 Using Organic Waste

open access: yesBiotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Global warming and industrial pollutants pose significant threats to environmental sustainability. In response, enzymes have emerged as promising tools for mitigating pollution. Enzymatic hydrolysis is considered environmentally sustainable due to its biological nature.
Gustavo Marques Serra   +4 more
wiley   +1 more source

Pulmonary vascular reactivity in severe pulmonary hypertension associated with COPD. [PDF]

open access: yesERJ Open Res
Jutant EM   +14 more
europepmc   +1 more source

Diffusion Coefficient and Viscosity of Methyl Viologen Electrolyte Estimation Based on a Kinetic Monte Carlo Computational Approach Coupled with the Mean Square Displacement Method

open access: yesBatteries &Supercaps, Volume 8, Issue 3, March 2025.
A novel and comprehensive 3D‐resolved kinetic Monte Carlo model coupled with mean square displacement analysis is introduced. This computational approach allows to explore, for the first time, the concentration and the state of charge effects on ionic diffusion coefficient and viscosity in methyl viologen‐based electrolytes used in organic redox flow ...
Jia Yu   +2 more
wiley   +1 more source

Pembrolizumab plus gemcitabine and cisplatin for advanced biliary tract cancer: longer-term follow-up from the randomised, double-blind, placebo-controlled, phase 3 KEYNOTE-966 trial. [PDF]

open access: yesEClinicalMedicine
Ueno M   +21 more
europepmc   +1 more source

Regulatory harmonization: Evolution, globalization and future directions

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm   +2 more
wiley   +1 more source

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