Results 81 to 90 of about 3,705 (178)

From Companion Diagnostics to Theranostics:A New Avenue for Alzheimer's Disease? [PDF]

open access: yes, 2016
The recent literature signals a growing paradigm shift toward integrating therapeutics and diagnostics rather than developing and deploying them separately.
Annachiara Gandini   +4 more
core   +2 more sources

Multicompartmental non-invasive sensing of postprandial lipemia in humans with multispectral optoacoustic tomography

open access: yesMolecular Metabolism, 2021
Objective: Postprandial lipid profiling (PLP), a risk indicator of cardiometabolic disease, is based on frequent blood sampling over several hours after a meal, an approach that is invasive and inconvenient.
Nikolina-Alexia Fasoula   +7 more
doaj   +1 more source

Real‐Time Monitoring of Atherosclerotic Plaque Using β‐Galactosidase‐Activated Photoacoustic Tomography

open access: yesSmall, Volume 21, Issue 44, November 6, 2025.
Detecting Vascular Senescence: Novel Enzyme‐Responsive Photoacoustic Nanoprobes for Atherosclerotic Plaque Imaging. A lipid nanoprobe is developed that detects senescence‐associated β‐galactosidase in plaques via enzyme‐triggered spectral shifts. This platform enables dynamic tracking of atherosclerotic progression, 3D visualization on the extent and ...
Yifan Zhou   +13 more
wiley   +1 more source

Novel analysis of second law and irreversibility for a solar power plant using heliostat field and molten salt

open access: yesEnergy Science & Engineering, 2020
Nowadays, the low efficiency of solar energy power plant systems brings about uneconomical performance and high‐cost uncompetitive industries compared with the traditional fossil fuel ones.
Mohammad Hossein Zolfagharnasab   +4 more
doaj   +1 more source

S1‐Leitlinie für bildgebende Diagnostik von Hauterkrankungen [PDF]

open access: yesJ Dtsch Dermatol Ges
Zusammenfassung Nichtinvasive Bildgebungstechniken erlauben schnell und schmerzfrei diagnostische Blicke in die Haut, je nach angewandter Methode mit unterschiedlich hoher Auflösung und Eindringtiefe. Schon seit Jahrzehnten aus dem Alltag nicht wegzudenken sind die etablierten Untersuchungsmethoden wie die Dermatoskopie und die hochauflösende ...
Deußing M   +21 more
europepmc   +2 more sources

Breaking (Light) Barriers: Photoacoustics in Atherosclerotic Diseases

open access: yesJournal of Cellular and Molecular Medicine, Volume 29, Issue 21, November 2025.
ABSTRACT Photoacoustic imaging (PAI) is an emerging imaging modality that provides high‐resolution, spatiotemporal insights into anatomical structures, functional parameters and molecular characteristics of tissues. By leveraging both endogenous absorbers, such as lipids and collagen, and exogenous contrast agents like nanoparticles and molecular dyes,
Kayleigh van Dijk, Margreet R. de Vries
wiley   +1 more source

In-vivo handheld optoacoustic tomography of the human thyroid

open access: yesPhotoacoustics, 2016
We interrogated the application and imaging features obtained by non-invasive and handheld optoacoustic imaging of the thyroid in-vivo. Optoacoustics can offer complementary contrast to ultrasound, by resolving optical absorption-based and offering ...
Alexander Dima, Vasilis Ntziachristos
doaj   +1 more source

Parameterized Communicating Automata: Complementation and Model Checking [PDF]

open access: yes, 2014
We study the language-theoretical aspects of parameterized communicating automata (PCAs), in which processes communicate via rendez-vous. A given PCA can be run on any topology of bounded degree such as pipelines, rings, ranked trees, and grids.
Bollig, Benedikt   +2 more
core   +3 more sources

Reduced Muscle Force in Dystrophic DMDΔ52 Pigs Is Incompletely Restored by Systemic Transcript Reframing (DMDΔ51–52)

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 5, October 2025.
ABSTRACT Background Duchenne muscular dystrophy (DMD) is a fatal X‐linked disease caused by mutations in the DMD gene, leading to dystrophin deficiency and progressive degeneration of skeletal and cardiac muscles. Pigs lacking DMD exon 52 (DMDΔ52) are a clinically severe model for DMD, mimicking molecular, functional and pathological hallmarks of the ...
Michaela Blasi   +17 more
wiley   +1 more source

Listening to reporter proteins: how loud does the message need to be? [PDF]

open access: yes, 2014
Optical imaging as non-invasive modality has tremendous research applications in the area of biomedical sciences such as characterization of cancerous cells.
Bohndiek, S. E.   +2 more
core  

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