Multispectral Optoacoustic Tomography (MSOT) for Imaging the Particle Size-Dependent Intratumoral Distribution of Polymeric Micelles [PDF]
International Journal of Nanomedicine, 2018 Zhaoqing Cong, Feifei Yang, Li Cao, Han Wen, Taotao Fu, Siqi Ma, Chunyu Liu, Lihui Quan, Yonghong Liao Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Institute of Medicinal Plant Development, Chinese Academy
Yong-Hong Liao, Li Cao, Lihui Quan
exaly +10 more sources
Photoacoustics, 2018 MultiSpectral Optoacoustic Tomography (MSOT) is an emerging imaging technology that allows for data acquisition at high spatial and temporal resolution.
Lacey R McNally +2 more
exaly +6 more sources
Performance of a Multispectral Optoacoustic Tomography (MSOT) System Equipped With 2D vs. 3D Handheld Probes for Potential Clinical Translation [PDF]
Photoacoustics, 2016 A handheld approach to optoacoustic imaging is essential for the clinical translation. The first 2- and 3-dimensional handheld multispectral optoacoustic tomography (MSOT) probes featuring real-time unmixing have recently been developed.
Stefan Harmsen +2 more
exaly +7 more sources
Fast multispectral optoacoustic tomography (MSOT) for dynamic imaging of pharmacokinetics and biodistribution in multiple organs. [PDF]
PLoS ONE, 2012 The characterization of pharmacokinetic and biodistribution profiles is an essential step in the development process of new candidate drugs or imaging agents.
Adrian Taruttis +4 more
doaj +6 more sources
Multispectral Optoacoustic Tomography (MSOT): Monitoring Neurovascular Changes in a Mouse Repetitive Traumatic Brain Injury Model [PDF]
Journal of Neuroscience Methods, 2023 Evidence suggests that mild TBI injuries, which comprise > 75% of all TBIs, can cause chronic post-concussive symptoms, especially when experienced repetitively (rTBI). rTBI is a major cause of cognitive deficit in athletes and military personnel and is associated with neurovascular changes.
Shyam S Mohapatra, Javier Cuevas
exaly +4 more sources
Quantitative, Real-Time in Vivo Tracking of Magnetic Nanoparticles Using Multispectral Optoacoustic Tomography (MSOT) Imaging [PDF]
Journal of Pharmaceutical and Biomedical Analysis, 2020 The goal of this work was to demonstrate real-time tracking of in vivo nanoparticle concentrations utilizing multispectral optoacoustic tomography (MSOT). Combining the high contrast of optical imaging with the high resolution of ultrasound imaging, MSOT was utilized for non-invasive, real-time tomographic imaging of particles in mice and the results ...
Andrew Brannen +2 more
exaly +5 more sources
Semi-Quantitative Multispectral Optoacoustic Tomography (MSOT) for Volumetric PK Imaging of Gastric Emptying [PDF]
Photoacoustics, 2014 A common side effect of medication is gastrointestinal intolerance. Symptoms can include reduced appetite, diarrhea, constipation, GI inflammation, nausea and vomiting. Such effects often have a dramatic impact on compliance with a treatment regimen. Therefore, characterization of GI tolerance is an important step when establishing a novel therapeutic ...
Stefan Morscher, Neal C Burton
exaly +4 more sources
WST11 Vascular Targeted Photodynamic Therapy Effect Monitoring by Multispectral Optoacoustic Tomography (MSOT) in Mice [PDF]
Theranostics, 2018 Objective: Monitoring emerging vascular-targeted photodynamic therapy (VTP) and understanding the time-dynamics of treatment effects remains challenging. We interrogated whether handheld multispectral optoacoustic tomography (MSOT) could noninvasively monitor the effect of VTP using WST11, a vascular-acting photosensitizer, on tumor tissues over time ...
Jaya Prakash +2 more
exaly +5 more sources
Investigating Age-Dependent Oxygenation and Blood Perfusion in a Mouse Model of Peripheral Artery Disease (PAD) Using Multispectral Optoacoustic Tomography (MSOT), Laser Speckle Contrast Imaging (LSCI) and Histology [PDF]
DiagnosticsBackground/Objectives: Peripheral artery disease (PAD) is frequently asymptomatic, requiring non-invasive approaches for disease evaluation and therapy monitoring.
Ralph Mason, Tam Nguyen, Kytai T Nguyen
exaly +4 more sources
Current and Emerging Clinical Applications of Multispectral Optoacoustic Tomography (MSOT) in Oncology. [PDF]
Clin Cancer Res, 2016 Abstract Accurate detection and characterization of cancers are key for providing timely intervention and effective treatments. Current imaging technologies are particularly limited when it comes to detecting very small tumors in vivo, i.e., very early cancers or metastases, differentiating viable tumor from surrounding dead tumor tissue,
McNally LR +6 more
europepmc +4 more sources