Results 11 to 20 of about 668,130 (171)

Multispectral Optoacoustic Tomography of Skeletal Muscle Unveils Microcirculation and Oxygen Metabolism Alterations in Sarcopenia [PDF]

Journal of Cachexia, Sarcopenia and Muscle
Background Sarcopenia, a significant geriatric syndrome, faces challenges in accurate diagnosis due to limitations of current imaging techniques. This study explores the novel application of multispectral optoacoustic tomography (MSOT) in evaluating ...
Ying Yang, Dan Wu, Yunqing Xv, Yonghua Xie, Xinsheng Wang, Yuanyuan Bi, Jing Zhang, Yun Wu, Yanting Wen, Shixie Jiang, Yiran Zhang, Tangming Peng, Zheng Li, Jiehao Chen, Xiaoyan Chen, Binglong Wang, Shanping Chen, Ming Yang, Huabei Jiang   +18 more
doaj   +3 more sources

Multispectral Optoacoustic Tomography (MSOT) of Human Breast Cancer [PDF]

Clinical Cancer Research, 2017
Abstract Purpose: In a pilot study, we introduce fast handheld multispectral optoacoustic tomography (MSOT) of the breast at 28 wavelengths, aiming to identify high-resolution optoacoustic (photoacoustic) patterns of breast cancer and noncancerous breast tissue.
Diot, G., Metz, S., Noske, A., Liapis, E., Schroeder, B., Ovsepian, S.V., Meier, R., Rummeny, E.J., Ntziachristos, V.   +8 more
openaire   +4 more sources

Multispectral optoacoustic tomography for non-invasive disease phenotyping in pediatric spinal muscular atrophy patients [PDF]

Photoacoustics, 2022
Proximal spinal muscular atrophy (SMA) is a rare progressive, life limiting genetic motor neuron disease. While promising causal therapies are available, meaningful prognostic biomarkers for therapeutic monitoring are missing.
Adrian P. Regensburger, Alexandra L. Wagner, Vera Danko, Jörg Jüngert, Anna Federle, Daniel Klett, Stephanie Schuessler, Adrian Buehler, Markus F. Neurath, Andreas Roos, Hanns Lochmüller, Joachim Woelfle, Regina Trollmann, Maximilian J. Waldner, Ferdinand Knieling   +14 more
doaj   +2 more sources

Non-invasive measurement of accelerated gastrointestinal transit in pediatric patients using Contrast-enhanced Multispectral optoacoustic tomography [PDF]

npj Imaging
Functional intestinal disorders are common; however, current imaging modalities are limited. Contrast-enhanced Multispectral optoacoustic tomography (CE-MSOT) represents a novel, non-invasive, and radiation-free imaging technique that enables assessment ...
Luisa Caselitz, Merle Claßen, Adrian Buehler, Lars-Philip Paulus, Henriette Grieshaber-Bouyer Mandelbaum, Emmanuel Nedoschill, Joachim Wölfle, André Hoerning, Ferdinand Knieling, Adrian Philip Regensburger, Felix Wachter   +10 more
doaj   +2 more sources

Edge-Aware Short-Chain Diffusion Enables High-Fidelity Sparse-Sampling Optoacoustic Tomography [PDF]

BME Frontiers
Objective: To improve image quality in multispectral optoacoustic tomography (MSOT) under conditions of strong noise and extreme sparse sampling. Impact Statement: This work provides a practical solution to enhance MSOT image quality while reducing ...
Ying Fan, Ting Feng, Yangkun Liu, Abdula Aji, Libo Jiang, Dean Ta   +5 more
doaj   +2 more sources

Spatial and Spectral Mapping and Decomposition of Neural Dynamics and Organization of the Mouse Brain with Multispectral Optoacoustic Tomography

Cell Reports, 2019
Summary: In traditional optical imaging, limited light penetration constrains high-resolution interrogation to tissue surfaces. Optoacoustic imaging combines the superb contrast of optical imaging with deep penetration of ultrasound, enabling a range of ...
Ivan Olefir, Ara Ghazaryan, Hong Yang, Jaber Malekzadeh-Najafabadi, Sarah Glasl, Panagiotis Symvoulidis, Valerie B. O’Leary, George Sergiadis, Vasilis Ntziachristos, Saak V. Ovsepian   +9 more
doaj   +2 more sources

Multispectral optoacoustic tomography of the human intestine – temporal precision and the influence of postprandial gastrointestinal blood flow

Photoacoustics, 2023
Multispectral optoacoustic tomography (MSOT) holds great promise as a non-invasive diagnostic tool for inflammatory bowel diseases. Yet, reliability and the impact of physiological processes during fasting and after food intake on optoacoustic signals ...
Lars-Philip Paulus, Alexandra L. Wagner, Adrian Buehler, Roman Raming, Jörg Jüngert, David Simon, Koray Tascilar, Alexander Schnell, Josefine Günther, Ulrich Rother, Werner Lang, André Hoerning, Georg Schett, Markus F. Neurath, Joachim Woelfle, Maximilian J. Waldner, Ferdinand Knieling, Adrian P. Regensburger   +17 more
doaj   +2 more sources

Mapping glucose-induced hemodynamics in white fat depots with label-free optoacoustics [PDF]

Photoacoustics
Subcutaneous adipose tissue (SAT) hemodynamics is an indicator of cardiometabolic health. Herein, we demonstrate a non-invasive approach for imaging SAT hemodynamics in humans using multispectral optoacoustic tomography (MSOT). We evaluated different SAT
Nikolina-Alexia Fasoula, Nikoletta Katsouli, Michael Kallmayer, Vasilis Ntziachristos, Angelos Karlas   +4 more
doaj   +2 more sources

Contrast‐Enhanced Multispectral Optoacoustic Tomography for Functional Assessment of the Gastrointestinal Tract [PDF]

Advanced Science, 2023
Real‐time imaging and functional assessment of the intestinal tract and its transit pose a significant challenge to conventional clinical diagnostic methods.
Lars‐Philip Paulus, Adrian Buehler, Alexandra L. Wagner, Roman Raming, Jörg Jüngert, David Simon, Koray Tascilar, Alexander Schnell, Ulrich Rother, Markus Eckstein, Werner Lang, André Hoerning, Georg Schett, Markus F. Neurath, Maximilian J. Waldner, Regina Trollmann, Joachim Woelfle, Sarah E Bohndiek, Adrian P. Regensburger, Ferdinand Knieling   +19 more
doaj   +6 more sources

Multispectral optoacoustic tomography (MSOT) scanner for whole-body small animal imaging

Optics Express, 2009
A major difficulty arising from whole-body optoacoustic imaging is the long acquisition times associated with recording signals from multiple spatial projections. The acquired signals are also generally weak and the signal-to-noise-ratio is low, problems often solved by signal averaging, which complicates acquisition and increases acquisition times to ...
Rui, Ma, Adrian, Taruttis, Vasilis, Ntziachristos, Daniel, Razansky   +3 more
openaire   +3 more sources