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Nucleotide Discrimination with DNA Immobilized in the MspA Nanopore [PDF]

open access: yesPLoS ONE, 2011
Nanopore sequencing has the potential to become a fast and low-cost DNA sequencing platform. An ionic current passing through a small pore would directly map the sequence of single stranded DNA (ssDNA) driven through the constriction.
Elizabeth A Manrao   +2 more
exaly   +5 more sources

Lipoteichoic acid biosynthesis by Staphylococcus aureus is controlled by the MspA protein [PDF]

open access: yesmBio
Staphylococcus aureus produces a plethora of virulence factors critical to its ability to establish an infection and cause disease. We have previously characterized a small membrane protein, MspA, which has pleiotropic effects on virulence and ...
Dora Bonini   +5 more
doaj   +5 more sources

MspA nanopores from subunit dimers. [PDF]

open access: yesPLoS ONE, 2012
Mycobacterium smegmatis porin A (MspA) forms an octameric channel and represents the founding member of a new family of pore proteins. Control of subunit stoichiometry is important to tailor MspA for nanotechnological applications.
Mikhail Pavlenok   +3 more
doaj   +4 more sources

Prevalence and phase variable expression status of two autotransporters, NalP and MspA, in carriage and disease isolates of Neisseria meningitidis. [PDF]

open access: yesPLoS ONE, 2013
Neisseria meningitidis is a human nasopharyngeal commensal capable of causing life-threatening septicemia and meningitis. Many meningococcal surface structures, including the autotransporter proteins NalP and MspA, are subject to phase variation (PV) due
Neil J Oldfield   +7 more
doaj   +7 more sources

Organic Matter Modeling at the Landscape Scale Based on Multitemporal Soil Pattern Analysis Using RapidEye Data [PDF]

open access: yesRemote Sensing, 2015
This study proposes the development of a landscape-scale multitemporal soil pattern analysis (MSPA) method for organic matter (OM) estimation using RapidEye time series data analysis and GIS spatial data modeling, which is based on the methodology of ...
Gerald Blasch   +3 more
doaj   +4 more sources

MSPA-informed SLEUTH urban growth modeling for green space protection in Ottawa. [PDF]

open access: yesPLoS ONE
We created optimal urban expansion scenarios that also safeguard green spaces using SLEUTH-3r in the National Capital Region, Ottawa, Ontario. The scenarios were based on using two exclusion layers in SLEUTH-3r modeling, adjustments to the model's ...
Abdolrassoul Salmanmahiny   +2 more
doaj   +2 more sources

Emerging oral Treponema membrane proteins disorder neutrophil phosphoinositide signaling via phosphatidylinositol-4-phosphate 5-kinase [PDF]

open access: yesFrontiers in Oral Health
BackgroundPeriodontitis (PD) is a group of inflammatory pathologies characterized by destruction of the tooth-supporting tissues. During PD, dysbiosis of the oral biofilm disrupts the host immune response and supports growth of pathogenic bacteria ...
Natalie K. Anselmi   +2 more
doaj   +2 more sources

Macrosphelide A Exhibits a Specific Anti-Cancer Effect by Simultaneously Inactivating ENO1, ALDOA, and FH

open access: yesPharmaceuticals, 2021
Aerobic glycolysis in cancer cells, also known as the Warburg effect, is an indispensable hallmark of cancer. This metabolic adaptation of cancer cells makes them remarkably different from normal cells; thus, inhibiting aerobic glycolysis is an ...
Kyoung Song   +14 more
doaj   +1 more source

Évaluation de la performance de la mesure conventionnelle et séquentielle de la pression artérielle en centre chez les patients en dialyse péritonéale à Dakar.

open access: yesBulletin de la Dialyse à Domicile, 2021
Introduction : L’objectif de cette étude était d’évaluer les performances des mesures conventionnelles (MCPA) et séquentielles (MSPA) de la pression artérielle en prenant la MAPA comme référence.
Moustapha Faye   +8 more
doaj   +1 more source

Aplicabilidade da versão brasileira da Multidimensional Scale for Invasive Developmental Disorder (MSPA-BR): explorando a sobreposição de TEA e TDAH

open access: yesDebates em Psiquiatria, 2022
Introdução: A avaliação de sintomas de transtornos do espectro autista e transtornos de déficit de atenção e hiperatividade em crianças é muitas vezes um desafio clínico, especialmente agora quando ambos os diagnósticos podem ser feitos no mesmo ...
Juliana Nassau Fernandes   +7 more
doaj   +1 more source

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