Results 231 to 240 of about 200,644 (275)

Adult T‐cell leukemia/lymphoma in French Guiana (1990–2019): Epidemiology, clinical features, and HTLV‐1 genetic diversity in the two main ethnic populations

open access: yesInternational Journal of Cancer, Volume 158, Issue 6, Page 1528-1540, 15 March 2026.
What's new? Adult T‐cell leukemia/lymphoma (ATL) is a rare and aggressive malignancy caused by human T‐cell leukemia virus type 1 (HTLV‐1). The authors comprehensively analyzed the epidemiological and clinical features of ATL over a 30‐year period in French Guiana, a region with high HTLV‐1 endemicity and a multiethnic population.
Jill‐Léa Ramassamy   +16 more
wiley   +1 more source

Targeting Expanded CUG and CTG Repeats as a Therapeutic Approach for Myotonic Dystrophy Type 1 (DM1)

open access: yesChemMedChem, Volume 21, Issue 5, 13 March 2026.
DM1 is an RNA gain‐of‐function disease caused by CTG repeat expansion, producing toxic r(CUG)exp RNA that sequesters MBNL1 and impairs splicing. This review covers the field of CUG and CTG ligands identified or rationally designed as DM1 drug candidates, highlighting their molecular design, RNA‐ or DNA‐binding modes, in vitro affinities and ...
Camille Richagneux, Anton Granzhan
wiley   +1 more source

Ungesättigte Phosphor‐Elektrophile zur Untersuchung von Protein‐Tyrosin‐Phosphatasen

open access: yesAngewandte Chemie, Volume 138, Issue 11, 9 March 2026.
Negativ geladene Aryl‐Ethynyl‐Phosphonamid‐ und Phosphonsäuren werden als reaktionsarme Elektrophile für peptidbasierte Aktivitätssonden eingeführt, die eine selektive, zielspezifische Profilierung von Protein‐Tyrosin‐Phosphatasen ermöglichen. Die Sonden zeigen keine Off‐Target‐Cystein‐Reaktivität und binden in der globalen Proteomanalyse nur an die ...
Eleftheria Poulou   +4 more
wiley   +1 more source

Reliability and state-dependency of EEG connectivity, complexity and network characteristics. [PDF]

open access: yesSci Rep
Dominicus LS   +11 more
europepmc   +1 more source

Efficacy and Safety of Atezolizumab Plus Bevacizumab for Patients With Hepatocellular Carcinoma and Child-Pugh Class B. [PDF]

open access: yesLiver Int
Sasaki R   +25 more
europepmc   +1 more source

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