Results 91 to 100 of about 6,450 (193)
MSX1 and PAX9 genetic alteration in Malaysian families with hypodontia [PDF]
, 2017 Hypodontia is characterized by the absence of one to six teeth. Malaysia has a high prevalence of hypodontia (2.8%). This study aimed to investigate the MSX1 mutation with clinical variability in Malaysian hypodontia families and to correlate the ...
Lestari, Widya +4 more
core
Advanced Paternal Age Impacts Common Loci in the Sperm and Placenta DNA Methylomes
Andrology, Volume 14, Issue 2, Page 528-544, February 2026.ABSTRACT Background Epidemiological studies have reported an association between advanced paternal age at conception and an increased risk of neurodevelopmental disorders in offspring, such as autism spectrum disorder. Evidence suggests that DNA methylation alterations in spermatozoa of older men may be transmitted to the feto‐placental unit and ...
Julia Barnwell +12 more
wiley +1 more source
MSX1-induced neural crest-like reprograming promotes melanoma progression.
, 2015 Melanoma cells share many biological properties with neural crest cells. Here, we show that the homeodomain transcription factor Msh homeobox 1 (MSX1), which is essential for neural crest specification, reprograms melanocytes towards a neural crest ...
Wei, Z. +11 more
core +1 more source
Prmt1 regulates craniofacial bone formation upstream of Msx1
Mechanisms of Development, 2018 Protein arginine methylation has been recently identified as an important form of post-translational modification (PTM). It is carried out by the protein arginine methyltransferase (PRMT) family of enzymes, which in mammals consists of nine members.
Yongchao Gou +9 more
openaire +2 more sources
MSX1 mutation in witkop syndrome; a case report.
Iranian journal of medical sciences, 2013 The Witkop syndrome is a rare autosomal dominant disorder characterized by the absence of several teeth and abnormalities of the nails. This is the first report of a rare genetic tooth and nail syndrome diagnosed in a 2.5-year-old boy with early exfoliation of the primary canine, absence of the primary incisors, and nail dysplasia.
Faezeh Ghaderi +3 more
openaire +2 more sources
Rôle de Msx1 dans l os (établissement d un modèle animal surexprimant Msx1 dans les ostéoblastes)
, 2013 Le but de mon travail de thèse fut de générer un modèle expérimental qui permette de comprendre les fonctions de Msx1 dans la minéralisation osseuse in vivo. Pour cela, un modèle de souris transgéniques fut établi à partir de l ADNc Msx1 sous le contrôle
BABAJKO, Sylvie, SENUSSI, Ibtisam
core
Identification of MSX1 mutation in Malaysian hypodontia family
, 2018 Hypodontia is defined as the absence of one to six teeth. There is high prevalence of hypodontia recorded in Malaysia (2.8%). This study aimed to identify any mutation of MSX1 in Malaysian family with hypodontia and its clinical finding.
Lestari, Widya +7 more
core +1 more source
Journal of Orofacial Sciences, 2016 Background and Aim: Recent studies demonstrate direct roles of different genes during formation of secondary palate, but there are no still data about local expression and distribution of gene products in cleft palate affected human tissue. Thus, the aim
Benita Krivicka-Uzkurele, Mara Pilmane
doaj +1 more source
Analyses of MSX1 regulation in T-ALL cell lines.
, 2017 (A) RQ-PCR analysis of MSX1 after siRNA-mediated knockdown of HHEX in LOUCY and after forced expression of HHEX in JURKAT demonstrated that HHEX activates MSX1 transcription.
Corinna Meyer (146293) +7 more
core +1 more source
MSX1 mutations isolated from tooth agenesis patients.
, 2020 (A) DNA sequence chromatograms presenting a de novo heterozygous missense mutation c.572T>G in MSX1 identified in family I, compared with wild-type control.
Le Yang (345935) +3 more
core +1 more source