Results 171 to 180 of about 6,450 (193)
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Development, 1998
ABSTRACT During early tooth development, multiple signaling molecules are expressed in the dental lamina epithelium and induce the dental mesenchyme. One signal, BMP4, has been shown to induce morphologic changes in dental mesenchyme and mesenchymal gene expression via Msx1, but BMP4 cannot substitute for all the inductive functions of ...
M, Bei, R, Maas
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ABSTRACT During early tooth development, multiple signaling molecules are expressed in the dental lamina epithelium and induce the dental mesenchyme. One signal, BMP4, has been shown to induce morphologic changes in dental mesenchyme and mesenchymal gene expression via Msx1, but BMP4 cannot substitute for all the inductive functions of ...
M, Bei, R, Maas
openaire +2 more sources
Msx1 Cooperates with Histone H1b for Inhibition of Transcription and Myogenesis
Science, 2004During embryogenesis, differentiation of skeletal muscle is regulated by transcription factors that include members of the Msx homeoprotein family. By investigating Msx1 function in repression of myogenic gene expression, we identified a physical interaction between Msx1 and H1b, a specific isoform of mouse histone H1.
Hansol, Lee +2 more
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Msx1 disruption leads to diencephalon defects and hydrocephalus
Developmental Dynamics, 2004AbstractWe have analyzed the expression of the Msx1 gene in the developing mouse brain and examined the brain phenotype in homozygotes. Msx1 is expressed in every cerebral vesicle throughout development, particularly in neuroepithelia, such as those of the fimbria and the medulla.
Casto, Ramos +4 more
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Bioinformatic Analysis of Msx1 and Msx2 Involved in Craniofacial Development
Journal of Craniofacial Surgery, 2014Msx1 and Msx2 were revealed to be candidate genes for some craniofacial deformities, such as cleft lip with/without cleft palate (CL/P) and craniosynostosis. Many other genes were demonstrated to have a cross-talk with MSX genes in causing these defects. However, there is no systematic evaluation for these MSX gene-related factors.
Jiewen, Dai +5 more
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[Msx1 and its influence on craniofacial growth].
L' Orthodontie francaise, 2007Many genes that interact in a complex and interdependent manner participate in the development of the craniofacial complex. One of them, the Msxl homeobox gene, a transcription factor, is expressed from early developmental stages to adulthood in accordance with specific spatio-temporal patterns.
Brigitte, Vi-Fane +2 more
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Orodental malformations associated with human MSX1 sequence variants
The Journal of the American Dental AssociationMSX1 sequence variants have been known to cause human tooth agenesis (TA) with or without orofacial clefts. However, their roles during the whole processes of tooth development are not fully understood. This study aimed to characterize a 4-membered family with TA carrying a novel MSX1 pathogenic variant and investigate the disease mechanism.The authors
Yin-Lin Wang +6 more
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MSX1 involved selective tooth agenesis and abnormal labial frenum, pedigree, and retrospective study
Oral Diseases, 2023Yulong Zhu, Yanli Zhang, Wenyan Ruan
exaly
Association of Polymorphic and Haplotype Variants of the MSX1 Gene and the Impacted Teeth Phenomenon
Genes, 2021Grzegorz Trybek +2 more
exaly
A novelMSX1 mutation in hypodontia
American Journal of Medical Genetics Part A, 2004Gert Matthijs, A Verdonck, C Carels
exaly
Msx1 and Dlx5 function synergistically to regulate frontal bone development
Genesis, 2010Junichi Iwata
exaly