Results 61 to 70 of about 5,286 (150)

De Novo Assembly and Comparative Analysis of the Complete Mitochondrial Genome of Mesenchytraeus (Annelida, Enchytraeidae)

Ecology and Evolution, Volume 16, Issue 9, September 2026.
This present the first mitochondrial genome dataset for 13 Mesenchytraeus species from the Changbai Mountain glacial refugium. Beyond characterizing standard genomic features, we perform comparative analyses of gene order, nucleotide composition, codon usage, and control region structure.
Juanjuan Chen, Horacio Naveira, Junqian Zhang, Naicheng Wu, Zhicai Xie   +4 more
wiley   +1 more source

Characterization of mitochondrial DNA mutations in colorectal cancer progression by in silico approach and use as potential biomarkers for diagnosis and prognosis

Egyptian Journal of Medical Human Genetics
Background Mitochondrial DNA variants are significant contributors to cancer progression, as evidenced by numerous findings. This study focuses on characterizing mitochondrial DNA mutations in colorectal cancer progression and their potential as ...
Ramya Gadicherla, Niraj Rai, Rajath Othayoth, Srinivasulu Kamma   +3 more
doaj   +1 more source

Mutationen in MT-ATP6 als Ursache von Spinocerebellärer Ataxie (SCA)

, 2018
Ataxia is known as an accompanying symptom of multisystemic mitochondrial disorders, some of which have been attributed to mutations in the MT-ATP6 gene. This gene encodes subunit a of the mitochondrial FoF1-ATP Synthase, also known as complex V, a vital component of cellular energy production.
Hofmann, Amrei, Justus Liebig University Giessen   +1 more
openaire   +3 more sources

Mitochondrial DNA mutations are associated with impaired oxidative phosphorylation and enhanced imatinib response in chronic myeloid leukemia

HemaSphere, Volume 10, Issue 9, September 2026.
Abstract Mitochondrial DNA (mtDNA) mutations are frequently observed in cancer, but their clinical and functional significance in chronic myeloid leukemia (CML) remains incompletely defined. Here, we show that a distinct mtDNA mutational landscape is associated with mitochondrial metabolic programs and response to imatinib therapy in CML.
Ilaria S. Pagani, Vaidehi Krishnan, John F. Ouyang, Chung H. Kok, BeiJun Chen, Kian Leong Lee, Cong M. Pham, Paul Wang, Elyse Page, Phuong Dang, Verity A. Saunders, Jane James, Kelly Lim, Stefano Mangiola, Yingnan Gao, Naranie Shanmuganathan, Agnes Yong, Susan Branford, Charles Chuah, David T. Yeung, Deborah L. White, Vignir G. Helgason, Daniel Thomas, S. Tiong Ong, Timothy P. Hughes, David M. Ross   +25 more
wiley   +1 more source

The complete mitochondrial genome of Cichla ocellaris

Mitochondrial DNA. Part B. Resources, 2017
In this study, the complete mitochondrial (mt) genome of Cichlao cellaris was determined. The mt genome has a length of 16,526 bp and encodes 13 protein-coding genes (PCGs), 22 transfer RNA genes, two ribosomal RNA genes, and one AT-rich non-coding ...
Minghui Lin, Xidong Mu, Xi Yan
doaj   +1 more source

Mitochondria‐targeted nanomedicine for cancer therapy: Targeting strategies, therapeutic mechanisms, and translational challenges

Interdisciplinary Medicine, Volume 4, Issue 5, September 2026.
This review highlights recent advances in mitochondria‐targeted nanomedicine for cancer therapy. It summarizes key targeting strategies and delineates four principal therapeutic mechanisms: oxidative stress–induced mitochondrial dysfunction, disruption of energy metabolism, direct mitochondrial damage, and induction of immunogenic cell death.
Linfeng Xiao, Xiaowei Chang, Jun Zhang, Yinshan Hong, Wenhui Cao, Zhewu Zhao, Yu‐E. Wang, Yanling Yang   +7 more
wiley   +1 more source

Absence of genetic structure in Baylisascaris schroederi populations, a giant panda parasite, determined by mitochondrial sequencing

Parasites & Vectors, 2014
Background Infection with the parasitic nematode, Baylisascaris schroederi (Ascaridida: Nematoda), is one of the most important causes of death in giant pandas, and was responsible for half of deaths between 2001 and 2005.
Yue Xie, Xuan Zhou, Zhihe Zhang, Chengdong Wang, Yun Sun, Tianyu Liu, Xiaobin Gu, Tao Wang, Xuerong Peng, Guangyou Yang   +9 more
doaj   +1 more source

Cerebellar Bottom of Fissure Hyperintensities in MT‐ATP6‐Associated Ataxia [PDF]

Annals of Neurology, 2022
Benjamin Roeben, Eva Bültmann, Claudia Stendel, Matthis Synofzik   +3 more
openaire   +3 more sources

Diagnostic Yield and Clinical Impact of Comprehensive WES/WGS Testing Beyond Common Genetic Causes in Hereditary Optic Atrophy

Clinical Genetics, Volume 110, Issue 3, Page 336-346, September 2026.
Opticus atrophy—Genetic testing with WES/WGS in 62 patients with optic atrophy provided a genetic diagnosis in 21 patients (33.9%). 42.9% of these involved non‐OPA1 genes, including WFS1, ACO2, NR2F1, UCHL1, CACNA1F, and COQ2, where the genetic diagnosis prompted additional clinical evaluation, surveillance, or therapeutic intervention.
Katrine M. Johannesen, Karen Grønskov, Line Kessel, Sarah Linea von Holstein, Lisbeth Birk Møller, Mette Kjøbæk Gundestrup Andersen, Marianne Søndergaard Khinchi, Steffen Hamann, Marianne Wegener, Mette Bertelsen   +9 more
wiley   +1 more source

Alternative DNA Markers to Detect Guam-Specific CRB-G (Clade I) Oryctes rhinoceros (Coleoptera: Scarabaeidae) Indicate That the Beetle Did Not Disperse from Guam to the Solomon Islands or Palau

Diversity
A partial mitochondrial DNA Cytochrome Oxidase subunit I (mtCOI) gene haplotype variant of the coconut rhinoceros beetle (CRB) Oryctes rhinoceros, classed as ‘CRB-G (clade I)’, has been the focus of much research since 2007, with reports of invasions ...
Wee Tek Tay, Sean D. G. Marshall, Angel David Popa-Baez, Glenn F. J. Dulla, Andrea L. Blas, Juniaty W. Sambiran, Meldy Hosang, Justine Bennette H. Millado, Michael Melzer, Rahul V. Rane, Tim Hogarty, Demi Yi-Chun Cho, Jelfina C. Alouw, Muhammad Faheem, Benjamin D. Hoffmann   +14 more
doaj   +1 more source