Results 51 to 60 of about 2,782,626 (284)
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Continuous loading of a magnetic trap [PDF]
, 2000 We have realized a scheme for continuous loading of a magnetic trap (MT). ^{52}Cr atoms are continuously captured and cooled in a magneto-optical trap (MOT). Optical pumping to a metastable state decouples atoms from the cooling light.
A.L. Migdall +29 more
core +2 more sources
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Robust Multiple Signal Classification via Probability Measure Transformation
, 2015 In this paper, we introduce a new framework for robust multiple signal classification (MUSIC). The proposed framework, called robust measure-transformed (MT) MUSIC, is based on applying a transform to the probability distribution of the received signals,
Hero, Alfred O., Todros, Koby
core +1 more source
What Level of Quality can Neural Machine Translation Attain on Literary Text? [PDF]
, 2018 Given the rise of a new approach to MT, Neural MT (NMT), and its promising performance on different text types, we assess the translation quality it can attain on what is perceived to be the greatest challenge for MT: literary text.
Toral, Antonio, Way, Andy
core +3 more sources
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Why to use mobile technology? [PDF]
, 2014 No holistic portrayal exists to map and discuss values deriving from mobile technology use. This empirical paper addresses this gap. To address research purpose adapted grounded theory approach is applied to collect and analyse in-depth interviews with ...
Bolat, Elvira
core
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
The impact of machine translation error types on post-editing effort indicators [PDF]
, 2015 In this paper, we report on a post-editing study for general text types from English into Dutch conducted with master's students of translation. We used a fine-grained machine translation (MT) quality assessment method with error weights that correspond ...
Daems, Joke +3 more
core +1 more source