Results 81 to 90 of about 2,782,626 (284)

PLuTO: MT for online patent translation [PDF]

, 2010
PLuTO – Patent Language Translation Online – is a partially EU-funded commercialization project which specializes in the automatic retrieval and translation of patent documents.
Sheridan, Páraic, Tinsley, John, Way, Andy   +2 more
core   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

El trabajo: concepciones de jóvenes que laboran en Call Centers en una ciudad intermedia colombiana

Revista Latinoamericana en Ciencias Sociales, Niñez y Juventud, 2017
Las organizaciones actuales han desarrollado nuevos modelos para almacenar, transferir y transformar la información; esta era se caracteriza por su alta demanda de las nuevas tecnologías y de las características del ...
Mariana Castaño-Ravagli, Claudia Milena Álvarez-Giraldo   +1 more
doaj  

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

PERFIL EPIDEMIOLÓGICO DE PACIENTES COM DOENÇA FALCIFORME QUE EVOLUÍRAM PARA ÓBITO, ATENDIDOS EM UM CENTRO DE REFERÊNCIA PÚBLICO EM MATO GROSSO

Hematology, Transfusion and Cell Therapy
Objetivo: Investigar o perfil epidemiológico dos pacientes com doença falciforme (DF), atendidos no Hemocentro Coordenador do estado de Mato Grosso (HC/MT), que evoluíram para óbito, entre 2002 e 2022.
SS Araujo, RCG Bezerra, BSN Souza, EGA Sá, MLP Perri, GHG Dib, GJ Nascimento   +6 more
doaj   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

GERAÇÃO X, Y E BABY BOOMERS: UM DESAFIO ATUAL PARA UMA ORGANIZAÇÃO DO SEGMENTO TECNOLÓGICO

Revista Estudos e Pesquisas em Administração, 2018
A globalização estimulou mudanças organizacionais, assim conhecer como as gerações  se comportam, em especial Baby Boomers, X e Y, torna-se estratégico para a produtividade e rentabilidade das empresas.
Moisés Phillip Botelho, Ederson Fernandes de Souza, Leni Fátima Ferreira, Rosicley Nicolau de Siqueira   +3 more
doaj   +1 more source

Solving headswitching translation cases in LFG-DOT [PDF]

, 2001
It has been shown that LFG-MT (Kaplan et al., 1989) has difficulties with Headswitching data (Sadler et al., 1989, 1990; Sadler & Thompson, 1991). We revisit these arguments in this paper. Despite attempts at solving these problematic constructions using
Way, Andy
core   +1 more source