Results 91 to 100 of about 374,164 (179)
, 2014 (A and B) Effects of knockdown of MT1-MMP by siRNA on the MT1-MMP protein and mRNA levels. ECs were transfected with siRNA to MT1-MMP. siRNA-mediated knockdown of MT1-MMP significantly reduced MT1-MMP protein levels and mRNA as compared to the scrambled ...
Kazuhiko Ikeda (402025) +5 more
core +1 more source
, 2012 MT1-MMP is a membrane-tethered enzyme capable of remodeling extracellular matrix. MT1-MMP-deficient mice exhibit systematic defects during development, especially in craniofacial development characterized by retarded calvarial bone formation.
Cao, Y, +7 more
core +1 more source
Analyses of MT1-MMP activity in cells.
, 2007 Membrane-type 1 matrix metalloproteinase (MT1-MMP) is a type I transmembrane protein which exhibits biological activities on the cell surface. One of the characteristic functions of this enzyme is activation of proMMP-2 on the cell surface (1).
Richard D. Evans, Yoshifumi Itoh
core +1 more source
UEG Week 2024 Poster Presentations
United European Gastroenterology Journal, Volume 12, Issue S8, Page 665-1360, October 2024.
wiley +1 more source
ZF21 regulates localization of MT1-MMP to invadopodia.
, 2013 MT1-MMP-pHLuorin (MT1-pHLuorin) was transiently expressed in the MDA-MB231 cells expressing either shLacZ or shZF21#1. The cells were cultured on cover slips coated with 50 µg/ml fibronectin for 6 hours.
Anri Saitoh (285400) +5 more
core +1 more source
TIMP-2 binding with cellular MT1-MMP stimulates invasion-promoting MEK/ERK signaling in cancer cells [PDF]
, 2010 peer reviewedBoth invasion-promoting MT1-MMP and its physiological inhibitorTIMP-2 play a significant role in tumorigenesis and are identified in the most aggressive cancers. Despite its antiproteolytic effects in vitro, clinical data suggest that TIMP-2
Dmitri V. Rozanov +10 more
core +1 more source
Factors associated with postpartum smoking relapse at early postpartum period of Japanese women in the Japan Environmental and Children's Study. [PDF]
Environ Health Prev Med, 2023 Anai A +10 more
europepmc +1 more source
NC1 α4(IV) overexpression decreases MT1-MMP activation and modifies MT1-MMP distribution.
, 2012 (A): Mock or NC1 α4(IV)-overexpressing cells were incubated for 48 h without FBS. MT1-MMP expression and activation in whole cell extracts were analyzed by Western blot with an antibody directed against the hinge region of MT1-MMP.
Karine Sénéchal (169044) +13 more
core +1 more source
In vitro characterization of the sensitivity of MT1-MMP biosensors.
, 2013 (A) Comparing the responses of different MT1-MMP biosensors upon the incubation with the catalytic domain of MT1-MMP (MT1-CAT). The substrate peptides are NL only (NL’), AHLR only (AHLR’), AHLR flanked by GGS linkers (AHLR”) or by GGSGGT linkers (AHLR ...
He Huang (50693) +8 more
core +1 more source
The impact of COVID-19 on blood donations. [PDF]
PLoS One, 2022 Veseli B +3 more
europepmc +1 more source