Results 101 to 110 of about 374,164 (179)

Melatonin signaling in mouse cerebellar granule cells with variable native MT1 and MT2 melatonin receptors

, 2008
Although G protein-coupled MT1 and MT2 melatonin receptors are expressed in neurons of the mammalian brain including in humans, relatively little is known about the influence of native MT1 and MT2 melatonin receptors on neuronal melatonin signaling ...
IMBESI, MARTA, MANEV H., GIUSTI, PIETRO, UZ T, DZITOYEVA S   +4 more
core   +1 more source

Anticancer Drug Conjugates Incorporating Estrogen Receptor Ligands. [PDF]

Pharmaceutics, 2022
Zlotos DP, Kronenberger T, Laufer SA.
europepmc   +1 more source

Eco-Geographical, Morphological and Molecular Characterization of a Collection of the Perennial Endemic Species Medicago tunetana (Murb.) A.W. Hill (Fabaceae) from Tunisia. [PDF]

Plants (Basel), 2021
Ferchichi Y, Sakhraoui A, Ltaeif HB, Ben Mhara Y, Elimem M, Ben Naceur M, Ghrabi-Gammar Z, Rouz S.   +7 more
europepmc   +1 more source

MT1-MMP-dependent and -independent regulation of gelatinase A activation in long-term, ascorbate-treated fibroblast cultures: Regulation by fibrillar collagen

, 2002
Human skin fibroblasts were cultured long-term in the presence of ascorbic acid to allow formation of a three-dimensional collagen matrix, and the effects of this on activation of secreted matrix metalloproteinase-2 (MMP-2) were examined. Accumulation of
Thompson, Erik W., Huang, X, Bateman, JF, Price, John T., Guenzler, V, Holmbeck, Kenn, Bateman, John F., Ruangpanit, Neeracha, Price, John T, Price, JT, Holmbeck, K, Chan, Danny, Ruangpanit, N, Thompson, EW, Bateman, John F, Thompson, Erik W, Guenzler, Volkmar, Birkedal-Hansen, Henning, BirkedalHansen, H, Chan, D, Huang, Xinfan   +20 more
core   +1 more source

Distribution of Melatonin MT1 Receptor Immunoreactivity in Human Retina

, 2002
Melatonin is synthesized in the pineal gland and retina during the night. Retinal melatonin is believed to be involved in local cellular modulation and in regulation of light-induced entrainment of circadian rhythms. The present study provides the first
Wirz‐Justice, Anna, Peter Meyer, Meyer, Peter, Müller-Spahn, Franz, Franz Müller-Spahn, Savaskan, Egemen, Jockers, Ralf, Olivieri, Gianfranco, Lena Brydon, Ralf Jockers, Gianfranco Olivieri, Mona Pache, Kurt Kräuchi, Kräuchi, Kurt, Pache, Mona, Brydon, Lena, Egemen Savaskan, Anna Wirz-Justice, Pache M, Brydon L, Savaskan E, Olivieri G, Kräuchi K, Jockers R, Wirz-Justice A, Müller-Spahn F, Meyer P   +26 more
core   +1 more source

Supplementary Figure 3 from CDCP1 Regulates the Function of MT1-MMP and Invadopodia-Mediated Invasion of Cancer Cells

, 2013
PDF File-139K, CDCP1 is not affecting MT1-MMP expression and pro-MT1-MMP activation by processing.
Yuumi Ito (508242), Motoharu Seiki (141191), Ryuichi Sakai (508243), Takamasa Uekita (3615485), Yuri Miyazawa (14898323), Hideki Yamaguchi (508239)   +5 more
core   +1 more source

Cooperation of MT1-MMP and receptor tyrosine kinase signalling in cancer cell invasion [PDF]

, 2013
Cancer metastasis is a stepwise process of cancer cell dissemination from a primary tumour into adjacent and distant tissues and causes around 90 % of cancer-associated mortality. Metastatic cancer dissemination is initiated and promoted by intracellular
Sugiyama, Nami
core  

MT1-MMP-dependent invasion is regulated by TI-VAMP/VAMP7.

, 2008
Proteolytic degradation of the extracellular matrix (ECM) is one intrinsic property of metastatic tumor cells to breach tissue barriers and to disseminate into different tissues.
Le Dez, Gaëlle, Chavrier, Philippe, Nassoy, Pierre, Steffen, Anika, Recchi, Chiara, Rottner, Klemens, Poincloux, Renaud, Galli, Thierry   +7 more
core   +1 more source

The Expanding Role of MT1-MMP in Cancer Progression

, 2019
For over 20 years, membrane type 1 matrix metalloproteinase (MT1-MMP) has been recognized as a key component in cancer progression. Initially, the primary roles assigned to MT1-MMP were the activation of proMMP-2 and degradation of fibrillar collagen ...
Gregg B. Fields, Anna M. Knapinska, Anna M. Knapinska, Gregg B. Fields   +3 more
core   +1 more source

Identifikace nových interakčních partnerů proteinu MT1-MMP [PDF]

Membrane Type 1 Matrix Metalloproteinase (MT1-MMP) is an enzyme with critical role in cancer cells invasiveness. In this work we aimed to investigate interaction partners of MT1-MMP to broaden our understanding of the processes the enzyme takes an active
Turchyna, Kateryna
core