Results 91 to 100 of about 11,642 (187)
Stem Cell Research & Therapy, 2019 Background With the development of regenerative medicine and tissue engineering technology, almost all stem cell therapy is efficacious for the treatment of premature ovarian failure (POF) or premature ovarian insufficiency (POI) animal models, whereas ...
Boxian Huang +5 more
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Pineal and cortical melatonin receptors MT1 and MT2 are decreased in Alzheimer's disease
European journal of histochemistry : EJH, 2006 The pineal hormone melatonin is involved in physiological transduction of temporal information from the light dark cycle to circadian and seasonal behavioural rhythms, as well as possessing neuroprotective properties. Melatonin and its receptors MT1 and MT2, which belong to the family of G protein-coupled receptors, are impaired in Alzheimer's disease (
Brunner, P. +8 more
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MT1/MT2 melatonin receptors in proinflammatory T helper cell populations
Russian Journal of ImmunologyMelatonin, a pineal gland hormone, is an effective regulator of the main T helper Th1 and Th17 populations. Currently, the studies of T helpers are shifting from classical to non-classical variants of these cells, primarily to Th1-polarized Th17 lymphocytes (Th17.1), which are formed in vitro and in vivo by transformation of differentiated Th17 cells ...
Elena M. Kuklina +2 more
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Light pollution during pregnancy influences the growth of offspring in rats
Ecotoxicology and Environmental SafetyObjective: To investigate the effects of excessive light exposure during gestation on intrauterine development and early growth of neonates in rats. Methods: Pregnant rats were randomly allocated to three groups: the constant light exposure group, non ...
Baojing Zhao +7 more
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AnimalsMammary cancer is a frequent disease in female dogs, where a high proportion of cases correspond to malignant tumors that may exhibit drug resistance. Within the mammary tumor microenvironment, there is a cell subpopulation called cancer stem cells (CSCs)
Dania Cataldo +5 more
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Genotype of melatonin receptor MT1 (MTNR1A) and puberty in Mediterranean Italian buffalo
Agriculturae Conspectus Scientificus, 2011 "In adult buffaloes, polymorphism of the MT1 receptor gene has shown to influence the reproductive seasonality. The aim of study was to assess whether the polymorphism of the MTNR1A gene may influence puberty in Mediterranean Italian buffalo. The study was conducted using 50 prepubertal buffalo cows that at the age of 15 months were placed into the ...
Carcangiu, Vincenzo +9 more
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Real-Time Determination of Intracellular cAMP Reveals Functional Coupling of Gs Protein to the Melatonin MT1 Receptor. [PDF]
Int J Mol SciTse LH, Cheung ST, Lee S, Wong YH.
europepmc +1 more source
New quinoxaline and indole derivatives as MT1 and MT2 receptor agonists
, 2014 There is a vast amount of studies which state that sleep is necessary for many functions, such as for encoding and consolidation of memory, for regulation of cognitive and emotional brain processes, for saving energy, for removing free radicals and for regulation of some neurotransmitters.
Ancizu, S. (Saioa) +2 more
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Structure of the melatonin-related orphan receptor, GPR50. [PDF]
Mol CellsShin J +7 more
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Physiological relevance of autocrine melatonin signaling in pineal and extrapineal sites: a systematic review. [PDF]
Function (Oxf)Ndinganire G +2 more
europepmc +1 more source