Therapies for Cardiovascular‐Kidney‐Liver‐Metabolic Syndrome: Reappraisal of Fibrates
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Cardiovascular disease, chronic kidney disease (CKD), type 2 diabetes mellitus (T2DM), obesity and metabolic dysfunction‐associated steatohepatitis (MASH) frequently coexist and share overlapping pathophysiology, forming the proposed cardiovascular‐kidney‐liver‐metabolic (CKLM) syndrome.
Virginia Anagnostopoulou +5 more
wiley +1 more source
Febuxostat Enhances the Antitumor Efficacy of 2-Fluoroadenine and 5'-Methylthioadenosine in MTAP-Deleted Cancer. [PDF]
Cancer Res CommunTang B +5 more
europepmc +1 more source
Dental Traumatology, EarlyView.ABSTRACT Introduction This study aimed to evaluate whether revitalization can be indicated in the treatment of traumatized immature teeth with external inflammatory root resorption (EIRR). Methods The protocol of the review was developed in accordance with the PRISMA checklist and registered in the PROSPERO database (CRD42023446609).
Ghina Al Khourdaji +4 more
wiley +1 more source
Fabrication and Characterization of a Trans-Activator of Transcription Peptide-Functionalized Collagen-Mineral Trioxide Aggregate Nanofiber Scaffold: Physicochemical Properties and Fibroblast Response. [PDF]
Clin Exp Dent ResSheikharabi M +3 more
europepmc +1 more source
Global Survey of Nutrition Education in Dental Schools: Current Practices and Opportunities
European Journal of Dental Education, EarlyView.ABSTRACT Background Nutrition is central to oral health, yet curriculum content and teaching approaches vary widely across dental schools globally. Aim To characterise current nutrition education practices in dental schools worldwide, identify regional variations, explore barriers and identify opportunities for curriculum enhancement.
Michael Crowe +4 more
wiley +1 more source
Comparative evaluation of NeoPUTTY and mineral trioxide aggregate for full pulpotomy in mature permanent molars with irreversible pulpitis: a randomized clinical study. [PDF]
Biomater Investig DentChawla S +4 more
europepmc +1 more source
Post‐Hoc Long‐Read Sequencing Links Leukemic Mutation Status to Single‐Cell Transcriptomes
European Journal of Haematology, EarlyView.ABSTRACT Single‐cell RNA‐sequencing‐based characterization of cells that belong to the neoplastic clone is a major challenge in hematologic neoplasms, where malignant and normal cells coexist. Confident molecular profiling requires simultaneous analysis of gene expression and genetic mutations in individual cells, an ability that is not supported by ...
Sofia Papavasileiou +8 more
wiley +1 more source
Outcomes and Associated Prognostic Factors for Orthograde Canal Obturation Using Ortho MTA III: A Randomised Prospective Clinical Trial. [PDF]
Int Endod JLee HJ +7 more
europepmc +1 more source
S‐Adenosylmethionine (SAM) hydrolases counter increased SAM epimerisation in thermophilic archaea
The FEBS Journal, EarlyView.S‐Adenosyl‐l‐methionine (SAM) is a vital enzyme cofactor. Epimerisation at the sulfonium centre of biologically active (SS,SCα)‐SAM is driven by heat, yielding biologically inactive (RS,SCα)‐SAM. Here, two novel archaeal SAM hydrolases from the thermophilic Sulfolobus acidocaldarius and the halophilic Haloferax volcanii are shown to cleave (RS,SCα)‐SAM.
Agnes Bartels +7 more
wiley +1 more source
Radiologic and cadaveric spatial relation between nasopalatine canal and the middle turbinate axilla. [PDF]
Acta Otorhinolaryngol ItalGaraycochea O +5 more
europepmc +1 more source