Results 81 to 90 of about 330,112 (309)

Membrane‐Active Peptide Protects Against Inflammation by Targeting NLRP3 Activation at the Trans‐Golgi Network

open access: yesAdvanced Science, EarlyView.
The membrane‐active peptide Pep19‐2.5 reduces harmful inflammation by blocking activation of the NLRP3 inflammasome at trans‐Golgi network membranes. By targeting key membrane interactions, Pep19‐2.5 suppresses inflammatory IL‐1β production and alleviates allergic airway inflammation in mice, leading to reduced immune cell infiltration and improved ...
Jonas Engelhardt   +16 more
wiley   +1 more source

Porkkanan varastotautiennuste

open access: yes, 1997
vokMyynti: MTT puutarhatuotannon tutkimuslaitos. Hinta: 5 raporttia yht.
Suojala, Terhi
core  

Moderni 100-vuotias suuntaa tulevaisuuteen. Maatalouden kannattavuuskirjanpidon juhlajulkaisu [PDF]

open access: yes, 2013
vokSaatavana MTT ...
Ahlstedt, Jaana (toim.)   +2 more
core  

A Glucose Metabolism‐Modulatory Nanobiohybrid Vaccine Platform Promotes Anti‐Tumor Immunity by Orchestrating Autophagy‐Dependent Cross‐Presentation and H2S‐Enhanced NLRP3 Inflammasome Signaling

open access: yesAdvanced Science, EarlyView.
A nanobiohybrid vaccine was designed by constructing a hydrogen‐bonded organic framework coencapsulated with glucose oxidase (GOx) and tumor antigens. This nanobiohybrid vaccine executed a GOx‐catalyzed enzyme reaction that disrupted glucose metabolism and induced redox imbalance in dendritic cells, leading to autophagy‐dependent antigen cross ...
Weidong Wang   +5 more
wiley   +1 more source

MTT vaalii Jokioisten kartanopuistoa

open access: yes, 2010
vo
Heikkilä, Juha
core  

Rewiring Pyroptosis to Potentiate Cancer Immunotherapy via a Gasdermin D Agonist Bypassing Caspase‐3

open access: yesAdvanced Science, EarlyView.
This work introduces a small‐molecule agonist, DIBDO, that bypasses Casp‐3 to directly trigger GSDMD‐mediated pyroptosis in tumors. Activated by glutathione, DIBDO generates singlet oxygen and molecular iodine, blocking Casp‐3 pathways and inducing immunogenic cell death.
Dan Zhao   +6 more
wiley   +1 more source

A comparison of purebred Holstein-Friesian and Holstein-Friesian × beef breed bulls for beef production and carcass traits

open access: yesAgricultural and Food Science, 2013
The objective of this study was to determine beef production traits of purebred Holstein-Friesian (Hol) and Hol×beef breed crossbred bulls. The data collected from slaughterhouses included observations of 87323 purebred Hol, 783 Hol×Aberdeen angus (Hol ...
Arto Kalevi Huuskonen   +3 more
doaj  

Genetic variation in meat production related traits in reindeer (Rangifer t. tarandus)

open access: yesRangifer, 2014
In reindeer husbandry, animal breeding could offer tools for improving productivity by selection. The traits affecting meat production efficiency are primarily related to calf growth and survival, and to dam’s longevity and lifetime ability to raise ...
Kirsi Muuttoranta   +5 more
doaj   +1 more source

Pollination between apple varieties named by MTT

open access: yes, 2003
vokMyynti MTT Tietopalvelut 31600 ...
Kinnanen, Hilma
core  

A Supramolecular Thermal Switch for Precision Pyroptosis via Host−Guest Recognition and Electrostatic Interactions

open access: yesAdvanced Science, EarlyView.
A supramolecular pyroptotic thermal switch encapsulates I3− within β‐cyclodextrin (β‐CD) and undergoes CaCO3 mineralization. Upon lysosomal acidification, CaCO3 is degraded, releasing Ca2+ and I3−. Concurrently, BODIPY activation converts I3− into I2, inducing oxidative stress and Ca2+ overload, which together trigger caspase‐3/GSDME‐mediated ...
Dan Wu   +8 more
wiley   +1 more source

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