Results 41 to 50 of about 21,992 (209)
Phosphate barriers may mitigate dissolved P losses from critical source areas. We studied P retention of industrially produced Ca–Fe oxide as potential P barrier material.
Risto Uusitalo +6 more
doaj
A multifunctional HA‐conjugated nanoplatform (HA‐PGMC) integrates CuO2, glucose oxidase, and mil‐100 to enable cascade catalytic ROS generation in tumor microenvironments. This self‐supplying ROS strategy induces immunogenic cell death, reprograms “cold” tumors into “hot” ones, and synergizes with PD‐L1 blockade, achieving potent chemodynamic ...
Man Lung Lee +6 more
wiley +1 more source
Profitability bookkeeping in the reindeer husbandry
See extended abstract in Full ...
Arto Latukka +2 more
doaj +1 more source
. ABSTRACT Neuroinflammation driven by microglial activation is a defining feature of Alzheimer's disease (AD), yet the molecular mechanisms sustaining this proinflammatory state remain unclear. Here, we identify the deubiquitinase OTUD7B as a critical regulator of microglial activation and AD pathology.
Luyao Li +15 more
wiley +1 more source
Strategic objectives and development plans of beginning farmers
Taking over the management and ownership of a farm contributes positively to farm growth but little is known about how farmers succeed after the starting phase.
Leena Rantamäki-Lahtinen +1 more
doaj
The aim of this work was to develop an index describing the relative intake of the total diet by dairy cows, and hence the ability to predict intake responses to changes in both forage and concentrate variables.
P. Huhtanen, M. Rinne, J. Nousiainen
doaj +1 more source
Engineered phage‐based trifunctional nanofibers are developed for synergistic biofilm eradication. Biofilm‐binding phages, armed with AuNPs and TCPP, serve as both warheads and scaffolds, endowing the phototherapy agents with biofilm‐anchoring ability. Upon light irradiation, AuNPs induce photothermal therapy, while TCPP generates 1O2 for photodynamic ...
Ying Cao +9 more
wiley +1 more source
Prolongation of the growing season due to a warming climate could represent new opportunities for northern agriculture. Climatic and biotic constraints may challenge future crop production.
Katri Rankinen +8 more
doaj
Dynamic Regulation of Endogenous Transcription Factor Hubs at Single‐Molecule Resolution
This study combines single‐molecule microscopy and genome editing to characterize the dynamic behaviors of endogenous oncofusion transcription factor EWS::FLI1 in Ewing sarcoma cells. EWS::FLI1 forms neomorphic hubs that dynamically assemble and dissolve. The hubs are regulated during mitosis, by RNA, and by specific chemicals.
Shawn Yoshida +4 more
wiley +1 more source
Protein crop production at the northern margin of farming: to boost or not to boost
Global changes in food demand resulting from population growth and more meat-intensive diets require an increase in global protein crop production, not least as climate change and increasing scarcity of fresh water could restrict future production.
Pirjo Peltonen-Sainio, Jarkko K. Niemi
doaj

