Results 61 to 70 of about 21,992 (209)
Tumor‐derived lactate establishes a metabolic lock that drives chemo‐immunotherapy resistance by suppressing PANoptosis. Mechanistically, KAT8 lactylates the mitochondrial translocator ANT2, which recruits PGAM5 to dephosphorylate CypD. This cascade restricts mitochondrial permeability transition pore opening, preventing pro‐inflammatory mtDNA leakage.
Sen Zhong +20 more
wiley +1 more source
Heritability of sow longevity and lifetime prolificacy in Finnish Yorkshire and Landrace pigs
The objective of this study was to estimate genetic parameters for longevity traits in Finnish pig populations. Analyzed traits were length of productive herd life (LPL), total number of parities (TNP), total number of piglets born (TNB), total number ...
Marja-Liisa Sevón-Aimonen, Pekka Uimari
doaj
The factors causing variation in birth date and birth weight were analysed from the data from an experimental reindeer herd consisting of 1136 calves with parental information. The traits had coefficient of variation of 37 and 14%, respectively.
Kirsi Muuttoranta +5 more
doaj +1 more source
ROS‐Responsive H2S Hydrogel (HAPPF) Coordinated Regeneration for High‐Quality Diabetic Wound Repair.A self‐regulating dynamic hydrogel is developed to deliver a fluorogenic H2S donor in response to excessive ROS. Released H2S acts as a master regulator to resolve chronic inflammation (M2 polarization), restore VEGF‐driven angiogenesis, and rebalance ...
Xuyang Ning +7 more
wiley +1 more source
The application of phosphorus (P)-sorbing materials offers a possible solution for treating municipal wastewater and agricultural runoff. In this paper we discuss P retention and release mechanisms, and review studies on the P retention of different ...
Aleksandar Klimeski +3 more
doaj
Radioresistance arises partly from tumor cells evading cuproptosis via unknown defenses. This study reveals that the PRMT5‐VPS34 axis acts as a radiation‐activated anticuproptotic mechanism: PRMT5 methylates VPS34 at Arg174, recruiting USP10 to remove K48‐linked ubiquitination and prevent degradation.
Wei Chen +17 more
wiley +1 more source
Risk, Information, and Trust in the Food Chain: Factors Explaining Consumer Willingness to Pay
This paper analysed factors contributing to consumers’ willingness to pay (WTP) for increased quality information. The empirical scope of the study was restricted to beef, because the beef labelling system enables reliable tracing of quality ...
Terhi Latvala
doaj
The HILA nanoplatform integrates HMnO2, LOX, and ICG to orchestrate multimodal therapy (starvation, chemodynamic, photodynamic, and photothermal) for achieving efficient colon cancer eradication. The established HMnO2‐LOX catalytic cycle continuously consumes lactate, acidifys microenvironment, relieves hypoxia, and generats reactive oxygen species ...
Yu‐E. Wang +11 more
wiley +1 more source
. Our study sought to determine the effects of normal vs high fish meal levels in the diet on the growing-furring process and apparent food digestibility of farmed male mink (Mustela vison).
HT Korhonen, P Niemelä
doaj
A NIR‐II light‐activatable thermoelectric nanoreactor converts surface‐bound Cu2+ into bioactive Cu+ via directed electron flow. This spatiotemporally controlled reduction triggers potent cuproptosis and immunogenic cell death, eradicating primary tumors and, together with aPD‐1 therapy, suppressing metastases while establishing durable immune memory ...
Boyu Yuan +10 more
wiley +1 more source

