Results 201 to 210 of about 330,112 (309)

Midazolam Reduces Metabolic Viability and Induces Apoptosis in MIA PaCa-2 Pancreatic Cancer Cells with Selective Transcriptional Modulation of Wnt and Hedgehog Components: A Preliminary In Vitro Study. [PDF]

Pharmaceuticals (Basel)
Korkmaz IF, Elgun T, Aktas C, Eslamkhah S, Sevinc SK, Yurttas AG.   +5 more
europepmc   +1 more source

Synthesis and Activity‐Based Protein Profiling Identifies Aldo‐Keto Reductase 1C3 as Target Protein of Myxoglucamides

Angewandte Chemie International Edition, EarlyView.
Myxoglucamide A—a novel glycolipopeptide isolated from myxobacteria—was synthesized, and activity‐based protein profiling identified aldo‐keto reductase 1C3 (AKR1C3) as its main target in human cells. Structure‐activity relationship studies, together with biophysical characterization and X‐ray crystallography, elucidated the structural basis of AKR1C3 ...
Thomas Siemon, Vivek K. Mishra, Mingming Zhao, Konrad Büssow, Alexander Popoff, Chengzhang Fu, Rolf Müller, Lothar Jänsch, Wulf Blankenfeldt, Mark Brönstrup   +9 more
wiley   +1 more source

Effects of <i>Boswellia serrata</i> on cell viability, scratch wound closure, and gene expression in human gingival fibroblasts. [PDF]

J Oral Biol Craniofac Res
Golmohammadi S, Daneshi Z, Anousheh M.
europepmc   +1 more source

Effect of calcium amendment on the calcium content and storage quality of carrot (Daucus carota L.)

European Journal of Horticultural Science, 2014
Terhi Suojala-Ahlfors, Tuija-Liina Laamanen   +1 more
doaj   +1 more source

Assessment of the Cytotoxic and Apoptotic Impacts of Bimetallic Zinc Iron Oxide Nanoparticles on HuH-7 Cell Line. [PDF]

Drug Des Devel Ther
Al-Malahi NM, Ali D, Alzahrani J, Alkahtani S, Almutairi BO, Alarifi S.   +5 more
europepmc   +1 more source

Preliminary Evaluation of SGLT2 Inhibitors in Human Bladder Cancer T24 Cells. [PDF]

Biomedicines
Szachniewicz M, Baran M, Gagat M, Hałas-Wiśniewska M.   +3 more
europepmc   +1 more source

MTT-Based Cytotoxicity Assessment of Chitosan- and Octenisept^®-Biomodified Mineral Trioxide Aggregate in Human Periodontal Ligament Fibroblasts. [PDF]

Biomimetics (Basel)
İlgenli I, İsmailoğlu E, İlhan P.
europepmc   +1 more source

Uncaging Iridium(III) Complexes for Combined Photodynamic and Photoactivated Chemotherapy

Angewandte Chemie International Edition, EarlyView.
Light‐activatable iridium(III) anticancer prodrugs demonstrate how chalcogen coordination controls photoinduced therapeutic activity. Upon visible‐light irradiation, sulfur‐ and selenium‐based caging ligands undergo distinct oxygen‐dependent photoreactions that trigger ligand release and singlet oxygen generation, enabling combined photoactivated ...
Victoria V. L. Müller, Dominik Moreth, Irene Regeni, Lan Wang, Sylvestre Bonnet, Ulrich Schatzschneider   +5 more
wiley   +1 more source

Exploring Tetrazolium Salt Reduction by Mono- and Bimetallic Nanoparticles as an Alternative Signal-Generation Strategy for Point-of-Care Diagnostics. [PDF]

Biosensors (Basel)
Stańczak P, Trzaskowski M, Pietrzak M.
europepmc   +1 more source

Innovative PLA or PCL‐Based Ocular Implants Obtained From Tape Casting or Electrospinning for Sustained‐Release Dexamethasone

Journal of Applied Polymer Science, EarlyView.
PLA and PCL ocular implants prepared by tape casting and electrospinning provide sustained dexamethasone release with distinct release profiles governed by polymer type and processing method. The relationship between polymer structure, degradation behavior, and drug release demonstrates the potential of these fabrication techniques for controlled ...
Renata Bochanoski, Henrique Borba Modolon, Ronaldo Silveira, Januara Rodrigues, Tiago Bender Wermuth, Sabrina Arcaro, Oscar R. K. Montedo   +6 more
wiley   +1 more source