Measurement of mitochondria amount and clearance using flow cytometry: effect of mitophagy inhibitors in leukemia cells. [PDF]
Kořánová T +2 more
europepmc +1 more source
The Gela/decitabine/La2(CO3)3 colloidal (GDLC) hydrogel developed here could reverse the epigenetic silencing of the GSDME gene by the synergistic interaction between DAC and La3+, while concurrently activating caspase‐3, thus facilitating pyroptosis induction under the tumor microenvironment.
Yang Hong +6 more
wiley +1 more source
Revisiting ISO 10993-5 In Vitro Cytotoxicity Standard Tests for Evaluation of Extracellular Matrix-Based Biomaterials. [PDF]
Ramakrishnan R, Daly AC.
europepmc +1 more source
Fluorescent Hydrogel‐Based Strain Sensor With Machine Learning‐Augmented Performance
Fluorescent hydrogel strain sensor based on carbon quantum dots enabling optical readout of deformation through strain‐dependent emission changes, coupled with Random Forest analysis to capture nonlinear fluorescence‐concentration relationships and identify optimal sensing conditions. Hydrogels are ideal matrices for bio‐integrated wearable sensors due
Tailai Chen +4 more
wiley +1 more source
Microsurgical Resection and Posterior Stabilization of a Delayed Solitary Thoracic Vertebral Metastasis From a Malignant Triton Tumor: A Case Report. [PDF]
Abdaev M, Kubetsky Y, Loparev E.
europepmc +1 more source
FluoAI is a two‐stage, label‐free method for quantifying nanomaterial‐induced cytotoxicity from conventional fluorescence microscopy images. Mask R‐CNN segmentation and DenseNet‐121 classification provide rapid live/dead classification matching human accuracy.
Ugur C. Topkiran +6 more
wiley +1 more source
Glutathione‐Responsive Acyl‐Modifications for Targeted RNA Decaging and Prolonged Protein Synthesis
The self‐immolation of disulfide‐based mRNA modifications in response to endogenous glutathione (GSH) promotes a gradual release of translatable mRNA within the cell, leading to improved nuclease resistance, tunable release properties, and a significant increase (up to 600%) of target protein production over time. This strategy offers an exciting proof
Mary E. Flood +6 more
wiley +2 more sources
Malignant triton tumor with thoracic region as the initial presentation: a case report. [PDF]
Yin H +8 more
europepmc +1 more source
Natural Aging of Biomaterials in Ambient and Physiological Environments
Biomaterials used in biomedical applications can change their physical properties over time, even under ambient and physiological conditions. This review highlights key studies on the natural aging of materials ranging from soft hydrogels to metals and ceramics, emphasizing how time‐dependent changes influence function and performance.
Shuyu Zhang, Anne E. Staples
wiley +1 more source
Towards standardizing cytotoxicity testing of 3D-printed orthodontic aligners and retainers: a scoping review. [PDF]
Tenge K +4 more
europepmc +1 more source

