Results 161 to 170 of about 338,901 (311)
Chemical Inhibition of Pyocyanin Biosynthesis Attenuates Virulence of Pseudomonas aeruginosa
Angewandte Chemie, EarlyView.Anti‐virulence strategies disarm pathogens rather than killing them directly. A β‐lactone reduces pyocyanin production without affecting growth. Chemical proteomics identified PqsC as the primary target via binding to Cys129. Crystallography revealed the binding mode, and SAR yielded a chloroacetamide inhibitor with improved enzymatic potency and anti ...
Wei Ding +3 more
wiley +2 more sources
Piparmintun menestyminen luonnonmukaisessa viljelyssä Ruukissa
, 2011 Seminaarin järjestäjät: MTT, Luonnonvarojen tutkimuslaitos, Ekologisen tuotannon tutkimusasema ja Agropolis ...
Aflatuni, Abbas +2 more
core
Advanced Science, EarlyView.A bioorthogonal “click‐to‐disassemble” strategy enables precise activation of self‐assembled phthalocyanine nanoassemblies for chemo‐photodynamic therapy. EGFR‐targeted activator triggers IEDDA‐mediated disruption of the quenched assemblies, restoring fluorescence and ROS generation while releasing tirapazamine.
Jiaxin Shen +4 more
wiley +1 more source
Nokkosen luonnonmukainen lannoitus- ja katekoe, Mikkeli, 1993-1995
, 2004 Seminaarin järjestäjät: MTT, Luonnonvarojen tutkimuslaitos, Ekologisen tuotannon tutkimusasema ja Agropolis ...
Valo, Ritva, Galambosi, Bertalan
core
Advanced Electronic Materials, EarlyView.In this study, we developed a cost‐efficient neural probe by replacing traditional gold with an aluminum‐based Ti/Al/Ni multilayer stack. Optimizing this metal architecture suppressed oxidation and ensured robust electrical stability, achieving signal quality comparable to standard gold probes. It enables a highly accessible and economical solution for
Sehwan Park +6 more
wiley +1 more source
Precision Matters: Minor Concentration Deviations of DMSO May Cause Major Efficacy Shifts
Angewandte Chemie, EarlyView.Low‐concentration dimethyl sulfoxide (DMSO) has long been regarded as biologically safe in drug discovery. However, increasing DMSO from 0.1% to 0.9% reduces photosensitizer PNA‐9 particle size from 657 nm to 260 nm, enhancing endocytosis and photodynamic therapy outcomes.
Sisi Yuan +6 more
wiley +2 more sources
Quercetin Differentially Modulates MTT-Derived Cellular Metabolic Activity and Apoptosis-Related Gene Expression in A549 and BEAS-2B Cells. [PDF]
MetabolitesÖzkan Vardar D, Duran T, Aydın M.
europepmc +1 more source
Kuminan kantakoe Mikkelissä v. 1992-1995
, 2004 Seminaarin järjestäjät: MTT, Luonnonvarojen tutkimuslaitos, Ekologisen tuotannon tutkimusasema ja Agropolis ...
Häkkinen, Seppo +3 more
core
Fluorescent Hydrogel‐Based Strain Sensor With Machine Learning‐Augmented Performance
Advanced Intelligent Discovery, EarlyView.Fluorescent hydrogel strain sensor based on carbon quantum dots enabling optical readout of deformation through strain‐dependent emission changes, coupled with Random Forest analysis to capture nonlinear fluorescence‐concentration relationships and identify optimal sensing conditions. Hydrogels are ideal matrices for bio‐integrated wearable sensors due
Tailai Chen +4 more
wiley +1 more source
Predictive Value of Combined Ultrasound Viscoelasticity Imaging, CEUS, AAPR, and PLR for Assessing Neoadjuvant Chemotherapy Efficacy in Breast Cancer. [PDF]
Breast Cancer (Dove Med Press)Li M, Shi J.
europepmc +1 more source