Results 91 to 100 of about 143,397 (262)
Selective Modulation of OTUB1 Noncanonical Function via a bioPhosTAC Strategy
This work positions the versatile performance of the peptide‐based bioPhosTAC platform for dissecting phosphorylation‐dependent biology and expanding the scope of induced‐proximity technologies. We demonstrated that selective manipulation of a tyrosine phosphorylation site is sufficient to propagate coordinated cellular consequences.
Seung Un Seo +7 more
wiley +1 more source
Natural‐Inspired Engineered Microalgae With Selenium Enrichment Enabled Potent Anti‐Tumor Immunity
Se‐Ssp was engineered as a potent immunomodulator for activating innate immunity via the TLR and cGAS‐STING pathways, therefore converting “cold” tumors into “hot” tumors to achieve high efficacy and long‐term therapeutic outcomes. ABSTRACT Immunotherapy has shed light on clinical oncology for several decades.
Yuqi Yang +11 more
wiley +1 more source
Selenium supplementation by addition of sodium selenate with silage additive
An ensiling experiment was conducted to assess the possibility for increasing the selenium content in grass silage by using a selenium-enriched silage additive, and to determine possible changes in the form of selenium during ensiling.
Arja Seppälä +5 more
doaj
Sadonkorjuun ajoittuminen vaikuttaa porkkanan varastokestävyyteen
vokMyynti: MTT puutarhatuotannon tutkimuslaitos. Hinta: 5 raportttia yht.
Suojala, Terhi, Aaltonen, Marja
core
Chromosome 16q loss drives genomic instability through disruption of the CYLD–TIRR–53BP1 axis. CYLD preserves homologous recombination by stabilizing TIRR and limiting 53BP1 accumulation at DNA double‐strand breaks. CYLD deficiency redirects repair toward error‐prone non‐homologous end joining, promotes mutational burden and homologous recombination ...
Mingming Lu +14 more
wiley +1 more source
MTT puutarhatuotannon jalostamat sekä FinE® -tavaramerkin saaneet lajikkeet
vokMyynti MTT Tietopalvelut 31600 ...
Juhanoja, Sirkka, Karhu, Saila
core
ABSTRACT Platinum‐based chemotherapy resistance remains a major obstacle in gastric cancer (GC) treatment. Through integrated transcriptomic profiling of cisplatin‐resistant xenografts and pharmacogenomic interrogation of the NCI‐60 dataset, we identified Prohibitin‐2 (PHB2) as a previously unrecognized determinant of chemoresistance.
Liang Xu +10 more
wiley +1 more source
Phosphorus acquisition by barley (Hordeum vulgare L.) at suboptimal soil temperature
We studied the effects of soil temperature (8 ºC and 15 ºC) on barley growth, barley phosphorus (P) uptake and soil P solubility. Barley was grown in a pot experiment in two soils with different P fertilization histories for 22 years. The availability of
Kari Ylivainio, Tommi Peltovuori
doaj

