Results 51 to 60 of about 137,652 (257)

Dynamic Regulation of Endogenous Transcription Factor Hubs at Single‐Molecule Resolution

Advanced Science, EarlyView.
This study combines single‐molecule microscopy and genome editing to characterize the dynamic behaviors of endogenous oncofusion transcription factor EWS::FLI1 in Ewing sarcoma cells. EWS::FLI1 forms neomorphic hubs that dynamically assemble and dissolve. The hubs are regulated during mitosis, by RNA, and by specific chemicals.
Shawn Yoshida, Yanghao Zhong, Akiko Kumagai, William G. Dunphy, Shasha Chong   +4 more
wiley   +1 more source

Strategic objectives and development plans of beginning farmers

Agricultural and Food Science, 2012
Taking over the management and ownership of a farm contributes positively to farm growth but little is known about how farmers succeed after the starting phase.
Leena Rantamäki-Lahtinen, Minna Katriina Väre   +1 more
doaj  

Evaluation of concentrate factors affecting silage intake of dairy cows: a development of the relative total diet intake index

Animal, 2008
The aim of this work was to develop an index describing the relative intake of the total diet by dairy cows, and hence the ability to predict intake responses to changes in both forage and concentrate variables.
P. Huhtanen, M. Rinne, J. Nousiainen
doaj   +1 more source

Porkkanalajikkeiden varastointikoe 1995

, 1997
vokMyynti: MTT puutarhatuotannon tutkimuslaitos. Hinta: 5 raporttia yht.
Suojala, Terhi
core  

Use of the “Ru‐1O2‐Hydrazide” System Catalyzed by Metallic Ruthenium Complexes to Decipher the Interaction Between Microbes and Host Cancer Cells

Advanced Science, EarlyView.
ABSTRACT The dynamic interplay between bacteria and host cancer cells plays a critical role in tumor microenvironment modulation, bacterial pathogenesis, and potential oncotherapy applications. However, traditional methods often fail to capture transient or spatially restricted molecular interactions at the bacteria‐cancer cell interface.
Amin Sun, Kaihong Wang, Haifu Sun, Kemei Tao, Xiang Li, Xiuhua Zhao, Shuang Qiu   +6 more
wiley   +1 more source

Climate change adaptation in arable land use, and impact on nitrogen load at catchment scale in northern agriculture

Agricultural and Food Science, 2013
Prolongation of the growing season due to a warming climate could represent new opportunities for northern agriculture. Climatic and biotic constraints may challenge future crop production.
Katri Rankinen, Pirjo Peltonen-Sainio, Kirsti Granlund, Hannu Ojanen, Mikko Laapas, Kaija Hakala, Kalle Sippel, Juha Helenius, Martin Forsius   +8 more
doaj  

Laadukasta keräkaalia myöhään syksyllä

, 1997
vokMyynti: MTT puutarhatuotannon tutkimuslaitos. Hinta: 5 raporttia yht.
Suojala, Terhi
core  

ZER1 Restrains Pressure Overload‐Induced Cardiac Remodeling by Targeting DVL2 for Gly/N‐Degron‐Dependent Degradation

Advanced Science, EarlyView.
Pressure overload suppresses cardiomyocyte ZER1, weakening CRL2Zer1‐mediated DVL2 degradation and allowing DVL2 accumulation. Elevated DVL2 activates CaMKII‐HDAC4‐MEF2C signaling, drives fetal gene reactivation, and promotes pathological remodeling.
Mingchao Jiang, Zhehao Lin, Lu Chen, Ying Ni, Jun Zhou, Wenjuan Zhang, Huilin Wang, Peifeng Ying, Xiu Lu, Kai Wang, Qingran Kong, Naxin Xu, Dingsheng Zhao, Jianwei Li, Guohui Zhong, Xingchen Meng, Sarkawt Hamad, Junmeng Zheng, Yuan Fu, Rongjiang Qin, Xuran Chu, Shangxuan Li, Youyou Li, Yili Wu, Yi Wang, Weihong Song, Yingxian Li, Shukuan Ling   +27 more
wiley   +1 more source

Protein crop production at the northern margin of farming: to boost or not to boost

Agricultural and Food Science, 2012
Global changes in food demand resulting from population growth and more meat-intensive diets require an increase in global protein crop production, not least as climate change and increasing scarcity of fresh water could restrict future production.
Pirjo Peltonen-Sainio, Jarkko K. Niemi
doaj  

SNeP: a tool to estimate trends in recent effective population size trajectories using genome-wide SNP data.

Frontiers in Genetics, 2015
Effective population size (Ne) is a key population genetic parameter that describes the amount of genetic drift in a population. Estimating Ne has been subject to much research over the last 80 years.
Mario eBarbato, Pablo Andrés Orozco-terWengel, Miika eTapio, Michael William Bruford   +3 more
doaj   +1 more source