PQB‐4, a fluorescent small‐molecule ligand that targets c‐MYC DNA G‐quadruplexes (G4s), showed marked synergy with gemcitabine in resistant PANC‐1 cells (CI = 0.027). In vivo, the ligand reduced tumor weight by 44% in a PANC‐1 xenograft model. These results highlight the therapeutic potential of c‐MYC DNA G4‐targeting ligands for treating gemcitabine ...
Bo‐Xin Zheng +10 more
wiley +2 more sources
Anu Koivisto, Tiina Hovi-Pekkanen
doaj +1 more source
Artificial seed in propagation of horticultural crops
vokMyynti MTT Tietopalvelut 31600 ...
Sorvari, Seppo
core
Curcumin-coated anodized titanium surfaces for enhanced in vitro cytocompatibility and early osteogenic activity. [PDF]
Suresh N +5 more
europepmc +1 more source
Development of an Experimental Protocol for Combined Electroporation and Phototherapy Treatment Against Melanoma Cells. [PDF]
Spugnini EP +3 more
europepmc +1 more source
Melatonin Differentially Modulates Temozolomide Responses in Glioblastoma and Endothelial Cells: Associations with Global DNA Methylation and Cortistatin Levels. [PDF]
Gundogan GI +5 more
europepmc +1 more source
Wir beschreiben die erste Germa‐Michael‐Addition zur Synthese eines wasserlöslichen Germanium‐Photoinitiators mit hoher Initiierungseffizienz, Stabilität und geringer Zytotoxizität. Ein NHS‐Ester eröffnet Möglichkeiten zur Biokonjugation, während doppelte Additionen das Funktionalisierungsspektrum erweitern.
Matthias Paris +13 more
wiley +1 more source
Mixture-Dependent Toxicity of E-Cigarette Constituents: Cytotoxicity, Inflammation, and DNA-Repair-Associated Protein Responses in Bronchial Epithelial Cells. [PDF]
Kabir E, Furst J, Muthumalage T.
europepmc +1 more source
The predictive value of preoperative ultrasound contrast parameters for early recurrence after transarterial chemoembolization for hepatocellular carcinoma. [PDF]
Jin S +5 more
europepmc +1 more source
Marjoram Extract Modulates Ion Currents, Intracellular Calcium Signaling, and MTT-Reducing Activity in Bovine Chromaffin Cells and Rat Cortical Neurons. [PDF]
de Pascual R +10 more
europepmc +1 more source

