Results 111 to 120 of about 1,060,750 (286)

A Glucose Metabolism‐Modulatory Nanobiohybrid Vaccine Platform Promotes Anti‐Tumor Immunity by Orchestrating Autophagy‐Dependent Cross‐Presentation and H2S‐Enhanced NLRP3 Inflammasome Signaling

open access: yesAdvanced Science, EarlyView.
A nanobiohybrid vaccine was designed by constructing a hydrogen‐bonded organic framework coencapsulated with glucose oxidase (GOx) and tumor antigens. This nanobiohybrid vaccine executed a GOx‐catalyzed enzyme reaction that disrupted glucose metabolism and induced redox imbalance in dendritic cells, leading to autophagy‐dependent antigen cross ...
Weidong Wang   +5 more
wiley   +1 more source

Cytotoxic effects of selective species of Caryophyllaceae in Iran [PDF]

open access: yesResearch Journal of Pharmacognosy, 2014
Cancer is a major cause of death worldwide and causes serious problems in human life. It is developed by uncontrolled growth of a cell or a group of cells.
F. Naghibi   +4 more
doaj  

In vitro antiproliferative activity of ethanolic extract of Sida cordifolia Linn against various cancer cell lines [PDF]

open access: yesAl Ameen Journal of Medical Sciences, 2020
Background: Sida cordifolia of family Malvaceae is traditionally, used in treating the various ailments of respiratory and urinary system. It possesses astringent and emollient properties.
Pratima M. Bhutkar   +3 more
doaj  

Cell Viability Assay (MTT Assay) Protocol v1

open access: yes, 2023
The purpose of this experiment is to investigate the effects of forskolin-mediated cAMP activation on the viability of LPS-treated Schwann cells. The immortalized rat RT4-D6P2T (ATCC #CRL-2768) and S16 (ATCC #CRL-2941) cell lines were cultured and received one of the following treatments: 0.1, 1, or 10 μg/mL of LPS, in N2 media (control) or N2 media ...
openaire   +1 more source

Concentrate feeding strategies for growing and finishing dairy bulls offered grass silage-based diets [PDF]

open access: yes, 2009
The first aim of this thesis was to produce data for evaluating, developing and recommending biologically and economically efficient energy and protein feeding strategies for growing and finishing dairy bulls offered grass silage-based diets and ...
Huuskonen, Arto
core  

Rewiring Pyroptosis to Potentiate Cancer Immunotherapy via a Gasdermin D Agonist Bypassing Caspase‐3

open access: yesAdvanced Science, EarlyView.
This work introduces a small‐molecule agonist, DIBDO, that bypasses Casp‐3 to directly trigger GSDMD‐mediated pyroptosis in tumors. Activated by glutathione, DIBDO generates singlet oxygen and molecular iodine, blocking Casp‐3 pathways and inducing immunogenic cell death.
Dan Zhao   +6 more
wiley   +1 more source

A Supramolecular Thermal Switch for Precision Pyroptosis via Host−Guest Recognition and Electrostatic Interactions

open access: yesAdvanced Science, EarlyView.
A supramolecular pyroptotic thermal switch encapsulates I3− within β‐cyclodextrin (β‐CD) and undergoes CaCO3 mineralization. Upon lysosomal acidification, CaCO3 is degraded, releasing Ca2+ and I3−. Concurrently, BODIPY activation converts I3− into I2, inducing oxidative stress and Ca2+ overload, which together trigger caspase‐3/GSDME‐mediated ...
Dan Wu   +8 more
wiley   +1 more source

Sitotoksisitas bahan restorasi cyanoacrylate pada variasi perbandingan powder dan liquid menggunakan MTT assay (Cytotoxicity of the cyanoacrylate restoration material with variation of powder and liquid ratio by using MTT assay)

open access: yesDental Journal, 2006
The requirements for dental material include not toxic, not irritant, no carcinogenic potential, nor cause an allergic response with the use in oral cavity. The cyanoacrylate restoration material has certain substance that can be toxic.
Asti Meizarini
doaj   +1 more source

Scratch wound healing and MTT assay.

open access: yes, 2016
(A-C) HCF, T1DM and T2DM cells were scratched and the relative cell migration distance was quantified at 0hr, 4hr, 24hr and 48hr time points. (D) Scratch assay quantification showing significant increase in cell migration distance in both T1DM and T2DMs ...
Shrestha Priyadarsini (662888)   +4 more
core   +1 more source

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