Results 211 to 220 of about 303,095 (340)

Synthesizing efficacious genistein in conjugation with superparamagnetic Fe₃O₄ decorated with bio-compatible carboxymethylated chitosan against acute leukemia lymphoma [PDF]

, 2014
A Kraay, A Mccloskey, A R Hall, A R Hall, B E Hansen, B E Hansen, C Audet, C Sanderson, C Sharpsteen, D Acemoglu, D Berkowitz, D Eddelbuettel, D Eddelbuettel, D Eddelbuettel, D Rodrik, D W K Andrews, D W K Andrews, D W K Andrews, D W K Andrews, F Schorfheide, Francis DiTraglia, G Claeskens, G Claeskens, G Claeskens, G Claeskens, G G Judge, G Kuersteiner, H Hong, H Leeb, H Leeb, H Leeb, H Leeb, J D Sachs, J Fox, J S Racine, K Carstensen, K Jana, Le Digabel, M Abramson, M Demetrescu, M J Silvapulle, N L Hjort, P C B Phillips, P Guggenberger, P Guggenberger, P Guggenberger, P Kabaila, P Kabaila, R Core Team, R L Berger, S G Donald, S G Donald, S T Buckland, T G Conley, W Easterly, W K Newey, W K Newey, W.-Y Loh, X Chen, X Cheng, X Cheng, Y Yang, Z Liao, Z Xiao   +63 more
core   +1 more source

Multifunctional Nano Immunostimulant: Overcoming Immunosuppressive Microenvironment for Antitumor Immunotherapy

Advanced Science, EarlyView.
A multifunctional nano immunostimulant is first proposed for efficient tumor immunotherapy. The ER targeted ability, superior ROS production, efficient GSH consumption, coupled with the HIF suppression, jointly arouses ICD/ferroptosis pathways to realize efficient tumor immunotherapy.
Guanhong Guo, Wenda Zhong, Huishuang Zhao, Yueying An, Xinyu Dong, Zhengbo Li, Shuangfeng Qin, Guangzhao Xu, Xiangguo Yue, Xudong Wang, Wen Sun, Zhe‐Sheng Chen, Weiguo Song, Liuya Wei, Fahui Li   +14 more
wiley   +1 more source

A Simplified Three‐Tailed N‐Alkyl Phosphoramidate Lipid Platform Enables Inguinal Adipose‐Accumulated mRNA Delivery for Anti‐Obesity Therapy

Advanced Science, EarlyView.
This study develops an mRNA therapy encoding a long‐acting GLP‐1/FGF21 fusion protein. A three‐tailed ionizable lipid engineered three‐component lipid nanoparticle delivers the mRNA to inguinal adipose tissue. In obese mice, this targeted, dual‐hormone treatment potently reduces body weight, fat mass, presenting a localized strategy for metabolic ...
Bin Ma, Yunxuan Liu, Huijuan Zhang, Yian Fang, Yizhe Xue, Junsheng Xue, Ziqiong Jiang, Tianyan Zhou, Yanyun Hao, Fei Xie, Lei Miao   +10 more
wiley   +1 more source

Comparison of chemosensitivity tests: clonogenic assay versus MTT assay.

Comparison of chemosensitivity tests: clonogenic assay versus MTT assay.
When the development of chemotherapeutic agents reaches the clinical trial stage, it is necessary to perform drug sensitivity tests quickly in order to select the most promising agents for the treatment of cancer. In order to assess the possibility of using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay as a substitute for
openaire   +1 more source

Predictive value of MTT assay as an in vitro chemosensitivity testing for gastric cancer: One institution's experience

, 2008
Bin Wu, Jin-Shui Zhu, Yi Zhang, Shen Weiming, Qiang Zhang   +4 more
openalex   +2 more sources

Biomimetic Nanomedicine for Senescence‐Modulated Immune Activation Enhances Immunotherapy Efficacy in Hepatocellular Carcinoma

Advanced Science, EarlyView.
A multifunctional mPDZM nanoplatform is developed in this study. mPDZM integrates chemotherapy‐induced senescence, selective senolysis, and STING‐mediated immune activation. mPDZM effectively clears senescent tumor cells, remodels the tumor immune microenvironment, and enhances antitumor T‐cell responses.
Shiji Fang, Liyun Zheng, Bin Lin, Jiale Chen, Dehai Hou, Yiming Ding, Mengzhu Han, Pan Qin, Mengyuan Wang, Xiaoju Guo, Yeyu Zhang, Gaofeng Shu, Fazong Wu, Jianfei Tu, Minjiang Chen, Zhongwei Zhao, Zhuang Liu, Jiansong Ji   +17 more
wiley   +1 more source

The Unreliability of MTT Assay in the Cytotoxic Test of Primary Cultured Glioblastoma Cells. [PDF]

Exp Neurobiol, 2015
Jo HY, Kim Y, Park HW, Moon HE, Bae S, Kim J, Kim DG, Paek SH.   +7 more
europepmc   +1 more source

Iron Oxide Nanozyme as Reactive Oxygen and Nitrogen Species Scavenger to Regulate Microglial Homeostasis in Stroke

Advanced Science, EarlyView.
6 nm iron oxide nanoparticles (IONP6) exhibit enzyme‐like activities that scavenge reactive oxygen and nitrogen species (RONS), including nitric oxide (NO). In stroke models, IONP6 promotes microglial polarization toward the M2 phenotype, reduces neuroinflammation, and improves neurological outcomes, offering a promising drug‐free approach to mitigate ...
Yilin Qi, Chunxiao Wang, Yuqing Miao, Jiamin Li, Zengyu Xun, Di Sun, Fei Xu, Minrui Liu, Heping Wang, Galong Li, Xuyi Chen, Haiming Fan, Xue Xue   +12 more
wiley   +1 more source

Correction: Evaluation of Direct Colorimetric MTT Assay for Rapid Detection of Rifampicin and Isoniazid Resistance in Mycobacterium tuberculosis. [PDF]

PLoS One, 2017
Hundie GB, Woldemeskel D, Gessesse A.
europepmc   +1 more source

MTT - VIABILITY ASSAY

, 2023
Jéssica Sodré Silva de Abreu, Janaína Fernandes   +1 more
openalex   +1 more source