Results 261 to 270 of about 303,095 (340)

Nanoclay‐Engineered Scaffolds for the Controlled Delivery of Biomolecules in Regenerative Medicine

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Regenerative medicine combines biomaterials, cells, scaffolds, and bioactive agents via modern technologies to aid in the reconstruction and repair of damaged tissues. Among these, nanoclay scaffolds have demonstrated unique advantages in facilitating the delivery of therapeutic agents.
Mehri Shadi, Saeed Vafaei‐Nezhad, Ahmad Gholamalizadeh Ahangar   +2 more
wiley   +1 more source

Stereoselective Cytotoxicity of Enantiopure 3,3-Dichloro-γ-lactams: Correlating In Vitro Activity with In Vivo Tolerability. [PDF]

Molecules
Diaba F, Teixidó E, Morán MDC.
europepmc   +1 more source

Tailored Dual Responsive Hybrid Gelatin Methacryloyl/Poly[2‐(Dimethylamino)Ethyl Methacrylate] Hydrogels for Efficient Ibuprofen Release in Topical Applications

Journal of Applied Polymer Science, EarlyView.
GelMA/DMAEMA hybrid hydrogels for release of ibuprofen. ABSTRACT In this study, biocompatible hydrogels intended for topical delivery of ibuprofen were synthesized from gelatin methacryloyl (GelMA) and 2‐(dimethylamino)ethyl methacrylate (DMAEMA) by varying their proportions. The impact of different GelMA and DMAEMA ratios was comprehensively evaluated
Guilherme Frey Schutz, Ana Luiza Assis Coutinho, Carolina Coli Zuliani, Ibsen Bellini Coimbra, Jéssica Heline Lopes da Fonseca, Marcos Akira d'Ávila, Ângela Maria Moraes, Roniérik Pioli Vieira   +7 more
wiley   +1 more source

Insights into the colloidal and structural stability of Atezolizumab with nonpolar amino acid-based ionic liquids under multiple stresses: phase two. [PDF]

RSC Adv
Alkhawaja B, Al-Akayleh F, Daadoue S, Alkhawaja N, AlDabet G, Nassereden J, Bustami M, Qinna N, Al-Remawi M, Watts AG.   +9 more
europepmc   +1 more source

Effect of rotenone on the L929 cell line assessed by the MTT assay.

Daria Sondej (21272981), Dominika Pigoń-Zając (21272984), Magdalena Jaszek (5345963), Dawid Stefaniuk (5345951), Anna Matuszewska (5345960), Kamil Bielak (3606254), Grzegorz Opielak (21272987), Teresa Małecka-Massalska (3325329), Mansur Rahnama-Hezavah (21272990), Monika Prendecka-Wróbel (21272993)   +9 more
openalex   +1 more source

Engineering Electrospun PCL/PEO Membranes With ECM‐Like Architecture and Tunable Hydrophilicity as Functional Wound Dressings

Journal of Applied Polymer Science, EarlyView.
Schematic illustration of the production of PCL/PEO electrospun membranes and their morphological, physical, and biological characterization. ABSTRACT Skin injuries resulting from trauma, burns, or chronic conditions such as diabetes often require advanced medical interventions, as conventional dressings provide only passive protection with limited ...
Ronaldo Bianchini da Silveira, Maria Fernanda Pedro Ebs, Renata Bochanoski, Mateus de Assunção Hofmann, Oscar Rubem Klegues Montedo, Thauan Gomes, Sabrina Arcaro   +6 more
wiley   +1 more source

Bacterial Pigments as Potential Antitumor Agents Against Gastrointestinal Cancers: A Comprehensive Systematic Review

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Gastrointestinal cancers (GICs) constitute one of the leading causes of cancer‐related morbidity and mortality worldwide. Despite currently available therapeutic strategies, new approaches and procedures are needed for their prevention and treatment.
Raúl Vergara, Ricardo F. S. Pereira, Carla C. C. R. de Carvalho, Jose Prados, Consolación Melguizo, Raul Ortiz   +5 more
wiley   +1 more source

Population pharmacokinetics of TBAJ‐587 and its main metabolites—Evaluation of different loading dose strategies and early dose selection

British Journal of Clinical Pharmacology, EarlyView.
Background and Aim The rise of drug‐resistant tuberculosis (TB) poses a need for new drugs and combinations. TBAJ‐587, a new diarylquinoline (DARQ), has shown promising efficacy in preclinical studies. This work aimed to describe the pharmacokinetics (PK) of TBAJ‐587 and its metabolites M2 and M3 after single ascending dosing in healthy volunteers and ...
Albin A. M. Leding, Paul Bruinenberg, Almari Conradie, Jerry Nedelman, Antonio Lombardi, Dean Hickman, Ulrika S. H. Simonsson   +6 more
wiley   +1 more source

MTT-based SARS-CoV-2 assay established

MTT-based SARS-CoV-2 assay ...
openaire   +1 more source

Model‐informed precision dosing of carboplatin in cancer patients by leveraging myelosuppression data from electronic health records

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims This study aimed to develop and validate a population pharmacokinetic‐pharmacodynamic (pop‐PK‐PD) model to describe carboplatin‐induced myelosuppression in cancer patients and support dose individualization. Methods Data from 580 cancer patients treated with carboplatin at Amsterdam UMC between 2019 and 2022 were used for model ...
Alessandro De Carlo, Elena Maria Tosca, Mirjam Crul, Tim Schutte, Lia van Zuijlen, Idris Bahce, Medhat M. Said, Jan Buter, Harmen Huls, Paolo Magni, Imke Bartelink   +10 more
wiley   +1 more source