Results 181 to 190 of about 21,687 (212)

Expression of MUC5AC in colorectal carcinoma and relationship with prognosis

Pathology International, 2002
Overexpression and alterations in the glycosylation of gastric mucins have been described in colorectal carcinoma. The purpose of our study was to confirm aberrant expression of MUC5AC in colorectal carcinoma, to investigate relationships between clinicopathological parameters and MUC5AC expression, and to determine if MUC5AC expression may be a ...
Belma Kocer, Betul Bozkurt
exaly   +3 more sources

MUC5AC in juvenile conjunctival nevus

Japanese Journal of Ophthalmology, 2011
To evaluate the possible role of cysts with mucins and inflammatory cells in rapid-growing juvenile conjunctival nevus.This was a case-control study at a university-based referral clinic. Seventeen conjunctival melanocytic lesions surgically excised from patients aged
Hsin-Chiung, Lin, Pao-Hsien, Chu, Shih-Ming, Jung, Meng-Ling, Yang, David Hui-Kang, Ma   +4 more
openaire   +2 more sources

MUC5AC overexpression in tear film of neonates

Graefe's Archive for Clinical and Experimental Ophthalmology, 2007
Full-term neonates produce tears normally, but neonatal tear film is modified to resist evaporation with a thick lipid layer that allows lower spontaneous blink rates. This adaptation presumably prevents drying of the ocular surface during long inter-blink periods.
Mantelli, Flavio, Tiberi, Eloisa, Micera, Alessandra, LAMBIASE, ALESSANDRO, Visintini, Federica, Bonini, Stefano   +5 more
openaire   +3 more sources

Quantification of MUC5AC Protein in Human Tears

Cornea, 2001
MUC5AC has been identified as a major secretory mucin of conjunctival goblet cells and precorneal tear film. However, no method has been reported to quantify MUC5AC protein in human tears. The objective of this study was to establish a method to measure the amount of MUC5AC in human tears and to correlate the amount of MUC5AC with age, gender, and dry ...
H, Zhao, J E, Jumblatt, T O, Wood, M M, Jumblatt   +3 more
openaire   +2 more sources

MUC1, MUC2 and MUC5AC expressions in cardiac myxoma

Virchows Archiv, 2004
Cardiac myxoma, the most common primary tumor of the heart, has a variable clinical presentation and immunohistochemical profile. An abundant mucopolysaccharidic matrix exists, including mucin, within cardiac myxoma. This investigation first reports the expressions of mucin genes in cardiac myxoma.A retrospective study was conducted between December ...
Pao-Hsien, Chu, Shih-Ming, Jung, Ta-Sen, Yeh, Hsin-Chiung, Lin, Jaw-Ji, Chu   +4 more
openaire   +2 more sources

The MUC5AC gene: RFLP analysis with the Jer58 probe

Human Genetics, 1995
We have recently obtained evidence that the locus corresponding to three groups of partial tracheobronchial cDNAs (A = Jer47, B = Jer57, C = Jer58) which mapped to chromosome 11p15 and was given the symbol MUC5 corresponds to two distinct genes which we have provisionally called MUC5B and MUC5AC.
P, Pigny, W S, Pratt, A, Laine, A, Leclercq, D M, Swallow, V C, Nguyen, J P, Aubert, N, Porchet   +7 more
openaire   +2 more sources

Effects of macromolecular crowding on the folding and aggregation of glycosylated MUC5AC

Biochemical and Biophysical Research Communications, 2020
To investigate the effects of macromolecular crowding on the folding and aggregation of MUC5AC with different levels of glycosylation during refolding.Part 1:An in vitro catalytic reaction comprising the ppGalNAc T2 enzyme, uridine-5'-diphospho-N-galactosamine (UDP-GalNAc) and an 11-amino acid peptide substrate, was used to assess the enzyme activity ...
Wen, Jing, Yalan, Qin, Jin, Tong
openaire   +2 more sources

Lipopolysaccharides induces MUC5AC overproduction in human nasal epithelium

European Archives of Oto-Rhino-Laryngology, 2012
Hyperproduction of mucin in the nasal epithelium is an important feature of nasal inflammatory diseases. We investigated the mechanism of lipopolysaccharides (LPS) involvement in mucin 5 subtype AC (MUC5AC) expression in human nasal epithelial cells. The primary human nasal epithelial cells were cultured in vitro, which were treated with LPS (10 nM/ml ...
Weiwei, Wang, Xianyan, Xu, Ming, Zheng, Lingyan, Wan   +3 more
openaire   +2 more sources

The role of autophagy in the overexpression of MUC5AC in patients with chronic rhinosinusitis

International Immunopharmacology, 2019
Autophagy is a lysosomal degradation pathway that protects the body and is essential for cell survival and differentiation. Mucins (MUCs) are important components of secreted mucus, mucin (MUC)5 AC is the major MUC secreted in the normal airway.Investigated the role of autophagy in pathogenic mucin (MUC)5 AC production during chronic rhinosinusitis ...
Yu, Ye, Junmei, Zhao, Jing, Ye, Xiaoyue, Jiang, Haitao, Liu, Yanhua, Xie, Jian, Zhang, Qing, Luo   +7 more
openaire   +2 more sources

The expression of MUC5AC in allergic rhinitis

Biochemical Society Transactions, 1997
S J, Wood, M A, Birchall, I, Carlstedt, A P, Corfield   +3 more
openaire   +2 more sources