Results 221 to 230 of about 22,602 (315)

Repurposing a Small Molecule Plant Hormone as a Tunable ON‐Switch for CAR‐T Cell Immunotherapy

open access: yesAdvanced Science, EarlyView.
By engineering a receptor system integrating the plant auxin receptor AFB1 with its co‐receptor IAA7, we enable ligand‐dependent interactions triggered by the plant hormone auxins. This design allows rapid, reversible, and dose‐dependent T cell activation, resulting in potent cytotoxicity against B‐cell lymphoma in vitro and in vivo.
Hongxiang Zeng   +16 more
wiley   +1 more source

Studies on the Mucilage from Rhodophyceae. (III)

open access: yesJournal of the agricultural chemical society of Japan, 1938
T. MORI, Y. TUTIYA
openaire   +5 more sources

Advances in Computational and Experimental Approaches to Chemical Short‐Range Order Formation in Multi‐Principal Element Alloys

open access: yesAdvanced Science, EarlyView.
Chemical short‐range order (CSRO) plays a central role in governing the behavior of multi‐principal element alloys. This perspective critically assesses computational and experimental approaches for quantifying, characterizing, and validating CSRO, emphasizing modeling–experiment cross‐validation pathways that enable more reliable interpretation of ...
Mohsen Asle Zaeem, Peter K. Liaw
wiley   +1 more source

Engineering Antibodies into Targeted Chimeras: From Recognition Modules to Programmable Degraders

open access: yesAdvanced Science, EarlyView.
Antibody can be engineered into diverse lysosome‐targeting chimeras that convert target recognition into active degradation. By coupling antibody binding with recruited receptors, encoded domains, conjugated ligands, or nanoparticle scaffolds, these antibody‐associated targeted chimeras (AbTACs) platforms direct extracellular and membrane proteins ...
Kaige Chen, Quanyin Hu
wiley   +1 more source

Plant mucilages. XXV. isolation and structural features of a mucilage, "abelmoschus-mucilage G", from the roots of abelmoschus glutinotextilis

open access: yesPlant mucilages. XXV. isolation and structural features of a mucilage, "abelmoschus-mucilage G", from the roots of abelmoschus glutinotextilis
抄録
openaire  

Nucleoside‐Modified mRNA Encoding Alpha‐Galactosidase A Ameliorates Fabry Disease Phenotypes in Human IPSC‐Derived Cardiomyocytes

open access: yesAdvanced Science, EarlyView.
Human iPSC‐derived Fabry cardiomyocytes exhibited broad transcriptional dysregulation, apoptosis, mitochondrial dysfunction, impaired reactive oxygen species handling, altered contractility, and abnormal calcium transient decay, potentially mediated by phospholamban hyperphosphorylation.
Malte Juchem   +24 more
wiley   +1 more source

Okra extract as a promising biopolymeric shield for robust <i>Bifidobacterium animalis</i> encapsulation and enhanced viability against processing and gastrointestinal stress. [PDF]

open access: yesCurr Res Food Sci
Chhe S   +9 more
europepmc   +1 more source

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