Results 91 to 100 of about 133,349 (299)
Exosomes and Exosomal miRNA in Respiratory Diseases [PDF]
, 2016 Exosomes are nanosized vesicles released from every cell in the body including those in the respiratory tract and lungs. They are found in most body fluids and contain a number of different biomolecules including proteins, lipids, and both mRNA and ...
Adcock, IM +5 more
core +4 more sources
High-resolution structure of intramolecularly proteolyzed human mucin-1 SEA domain
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2020 SEA domains are ubiquitous in large proteins associated with highly glycosylated environments. Certain SEA domains undergo intramolecular proteolysis involving a nucleophilic attack of a serine hydroxyl group on the preceding glycine carbonyl. The mucin-1 (MUC1) SEA domain has been extensively investigated as a model of intramolecular proteolysis ...
Noguera, Martín Ezequiel +2 more
openaire +4 more sources
Advanced Materials Technologies, EarlyView.A spiral microfluidic chip is compared with ultrafiltration for the separation of extracellular vesicles (EVs). The method preserves miRNA cargo and membrane integrity more effectively, resulting in intact vesicle morphology and consistent surface biomarker expression.
Huiseop Lee +5 more
wiley +1 more source
Respiratory Research, 2007 Background Nitric oxide (NO) is generally increased during inflammatory airway diseases. This increased NO stimulates the secretion of mucin from the goblet cell and submucosal glands but the mechanism is still unknown precisely.
Kim Kwan +8 more
doaj +1 more source
Mucin 1 Aberrantly Expresses in Goat Mammary Carcinoma [PDF]
Journal of Stem Cell Research & Therapeutics, 2017 The objective of this study was to determine if expression of mucin MUC and abundance of collagen fibers is associated with the incidence of goat mammary cancer MUC often expressed in metastatic cancers and has been used as a diagnostic marker for metastatic progression Similarly collagen density affects tumor microenvironment and promotes invasion ...
openaire +1 more source
Regulation of mucin 1 expression and its relationship with oral diseases
Archives of Oral Biology, 2020 The aim of this study is to describe the polymorphic mucin 1 (MUC1), and to provide an overview of the known complex and multiple functions of MUC1 in normal oral mucosa and oral mucosal lesions in compromised situations as well as exploring the challenges associated with the heterogeneous nature of MUC1.
Kashyap, Bina, Kullaa, Arja M
openaire +4 more sources
Advanced Materials Technologies, EarlyView.ABSTRACT Quantifying oral polymorphonuclear neutrophils (oPMNs) is a clinically validated approach for assessing periodontal inflammation. However, current methods, such as manual hemocytometry and flow cytometry, are time‐consuming (>3 h), require invasive sampling, and depend on staining and complex instrumentation, making them unsuitable for point ...
Mohsen Hassani +9 more
wiley +1 more source
Journal of Lipid Research, 2004 Gallbladder mucins play a critical role in the pathogenesis of cholesterol gallstones because of their ability to bind biliary lipids and accelerate cholesterol crystallization.
Helen H. Wang +3 more
doaj +1 more source
Mucin adsorbed by E. coli can affect neutrophil activation in vitro
FEBS Open Bio, 2020 Bacteria colonizing human intestine adhere to the gut mucosa and avoid the innate immune system. We previously demonstrated that Escherichia coli isolates can adsorb mucin from a diluted solution in vitro.
Elena Mikhalchik +11 more
doaj +1 more source
N-glycans of human amniotic fluid transferrin stimulate progesterone production in human first trimester trophoblast cells in vitro [PDF]
, 2004 Aims: During pregnancy, the placenta produces a variety of steroid hormones and proteins. Several of these substances have been shown to exert immunomodulatory effects.
Briese, V. +8 more
core +1 more source