Results 51 to 60 of about 21,379,209 (297)
Frontiers in Bioengineering and BiotechnologyWith a prevalence of 12.5% of all new cancer cases annually, breast cancer stands as the most common form of cancer worldwide. The current therapies utilized for breast cancer are constrained and ineffective in addressing the condition.
Rajesh Salve +13 more
doaj +1 more source
Journal of Applied Sciences and Environmental Management, 2015 The objective of this study was to investigate the effect of alkali treatment of mucin on the mucoadhesive properties and tablet parameters of metronidazole tablets.
SO Eraga +3 more
doaj +1 more source
Incessant Ovulation, Mucin 1 Immunity, and Risk for Ovarian Cancer [PDF]
Cancer Epidemiology, Biomarkers & Prevention, 2007 Abstract Background: Risk for ovarian cancer correlates directly with “ovulatory years or cycles” estimated from time not pregnant, breast-feeding, or using oral contraceptives. Recently, we reported that several factors known to reduce ovarian cancer risk may operate by inducing antibodies against mucin 1 (MUC1), a glycoprotein ...
Kathryn L, Terry +5 more
openaire +2 more sources
Pharmaceutical and Biomedical Research, 2020 Background: The transdermal delivery of insulin involving the use of polymers has been extensively reported. More recently, the use of mucoadhesive or bioadhesive polymers as an insulin base in its formulation is gaining attention possibly due to the ...
Sylvester O. Eraga +2 more
doaj +1 more source
Glycosylation pattern of brush border-associated glycoproteins in enterocyte-like cells: involvement of complex-type N-glycans in apical trafficking [PDF]
, 2009 We have previously reported that galectin-4, a tandem repeat-type galectin, regulates the raft-dependent delivery of glycoproteins to the apical brush border membrane of enterocyte-like HT-29 cells.
Huet, Guillemette +8 more
core +1 more source
Induction of Colonic Aberrant Crypts in Mice by Feeding Apparent N-Nitroso Compounds Derived From Hot Dogs [PDF]
, 2012 Nitrite-preserved meats (e.g., hot dogs) may help cause colon cancer because they contain N-nitroso compounds. We tested whether purified hot-dog-derived total apparent N-nitroso compounds (ANC) could induce colonic aberrant crypts, which are putative ...
Mirvish, Sidney S. +12 more
core +1 more source
Mucin 1 Regulates Cox-2 Gene in Pancreatic Cancer [PDF]
Pancreas, 2015 Eighty percent of pancreatic ductal adenocarcinomas (PDAs) overexpress mucin 1 (MUC1), a transmembrane mucin glycoprotein. MUC1(high) PDA patients also express high levels of cyclooxygenase 2 (COX-2) and show poor prognosis. The cytoplasmic tail of MUC1 (MUC1-CT) partakes in oncogenic signaling, resulting in accelerated cancer progression.
Nath, Sritama +4 more
openaire +2 more sources
Lubiprostone stimulates small intestinal mucin release
BMC Gastroenterology, 2012 Background Lubiprostone is a synthetic bicyclic fatty acid derivative of prostaglandin E1 (PGE1) used for chronic constipation. The best known action of lubiprostone is simulation of Cl- dependent fluid secretion.
De Lisle Robert C
doaj +1 more source
Mucin-enrichment metabolite profiling.
, 2016 (A) short chain fatty acids (n = 8) and (B) amino acids (n = 10) were quantified in mucin enrichment cultures. Arginine and cysteine were unable to be quantified due to their co-elution with other metabolites.
Jordan M. Dunitz (3069192) +3 more
core +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source