Results 91 to 100 of about 29,843,857 (288)
Journal of Lipid Research, 2004 Gallbladder mucins play a critical role in the pathogenesis of cholesterol gallstones because of their ability to bind biliary lipids and accelerate cholesterol crystallization.
Helen H. Wang +3 more
doaj +1 more source
Mucin 1 Oncoprotein Expression Is Suppressed by the miR-125b Oncomir
Genes & Cancer, 2010 The MUC1 oncoprotein is overexpressed in most human breast cancers by mechanisms that are incompletely understood. The microRNA, miR-125b, is downregulated in breast cancer cells. The present studies demonstrate that the MUC1 3'UTR contains a site for binding of the miR-125b seed region.
Rajabi, H +5 more
openaire +3 more sources
Advanced Science, EarlyView.Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha +4 more
wiley +1 more source
Animal Nutrition, 2016 Mucin 2 and occludin play a crucial role in preserving the intestinal mucosal integrity. However, the role for leucine mediating intestinal mucin 2 and occludin expression has little been investigated.
Xiangbing Mao +4 more
doaj +1 more source
Mucin adsorbed by E. coli can affect neutrophil activation in vitro
FEBS Open Bio, 2020 Bacteria colonizing human intestine adhere to the gut mucosa and avoid the innate immune system. We previously demonstrated that Escherichia coli isolates can adsorb mucin from a diluted solution in vitro.
Elena Mikhalchik +11 more
doaj +1 more source
Membrane-Tethered Mucin-like Polypeptides Sterically Inhibit Binding and Slow Fusion Kinetics of Influenza A Virus [PDF]
, 2019 The mechanism(s) by which cell-tethered mucins modulate infection by Influenza A viruses (IAVs) remains an open question. Mucins form both a protective barrier that can block virus binding and recruit IAVs to bind cells via the sialic ...
Corleone, Delaveris +4 more
core +1 more source
Pellicle Modification with Casein and Mucin Does Not Promote In Vitro Bacterial Biofilm Formation. [PDF]
, 2020 PURPOSE During biofilm formation, bacterial species do not attach directly onto the enamel surface, but rather onto the salivary pellicle. Salivary pellicle modification with casein and mucin can hinder erosive demineralisation of the enamel, but it ...
Saads Carvalho, Thiago +5 more
core +1 more source
Advanced Science, EarlyView.The microalgae‐nanoparticle hybrid system with antibacterial activity can improve the oral delivery and therapeutic efficiency for hepatic encephalopathy treatment. Oral administration of the system can reduced systemic ammonia levels, enhanced intestinal barrier function, attenuated systemic and neuroinflammation, ameliorated cognitive impairments ...
Kaiyue Wang +8 more
wiley +1 more source
, 2017 Objective. Mucin (MIX) 20 has recently been implicated to play a role in human carcinogenesis. However, the role of MUC20 in epithelial ovarian cancer (EOC) remains to be elucidated. Methods.
陳啟豪;林鶴雄;黃敏銓;徐明洸 +1 more
core +1 more source
Advanced Science, EarlyView.Aberrant GALNT7‐mediated O‐GalNAcylation stabilizes TAZ to drive gallbladder cancer progression through a feed‐forward transcriptional loop. Structure‐based screening identifies Olaparib as a potent GALNT7 antagonist that disrupts this oncogenic axis, providing an immediate therapeutic strategy for this aggressive malignancy.
Peng Qiu +11 more
wiley +1 more source