Results 221 to 230 of about 131,847 (256)

Aptamer-Gated Ion Channel for Ultrasensitive Mucin 1 Detection

Analytical Chemistry, 2021
Detection of cancer markers is important for early diagnosis and timely treatment of cancer. In this study, we fabricated a tailorable gold nanofilm-anodized aluminum oxide (Au-AAO) ion channel through nanoparticle self-assembly and proposed a highly sensitive and selective Mucin 1 (MUC1) detection method.
Mengying Pan, Jiarong Cai, Si Li, Liguang Xu, Wei Ma, Chuanlai Xu, Hua Kuang   +6 more
openaire   +2 more sources

Designer Tridentate Mucin 1 Aptamer for Targeted Drug Delivery

Journal of Pharmaceutical Sciences, 2012
A single-stranded DNA aptamer (APT) capable of targeting mucin 1 (MUC1) extracellular protein was modified to increase its drug delivery specificity toward MUC1 overexpressing cancer cell line, MCF7. The active targeting region of APT was truncated and variable repeats (one, two, or three) of this sequence were synthesized. An aptamer formed from three
Tan, L., Gee Neoh, K., Kang, E.-T., Choe, W.-S., Su, X.   +4 more
openaire   +2 more sources

CTL in mice immunized with human mucin 1 are MHC-restricted

The Journal of Immunology, 1995
Abstract CTLs that recognize tumor Ags have been described in mice and humans, particularly for melanoma. These CTLs are CD8+, which is MHC-restricted. In contrast, in human carcinomas of the breast, pancreas, or ovary, and in multiple myeloma, CD8+ CTLs have been described that lyse targets expressing human MUC1 in a non-MHC ...
V, Apostolopoulos, B E, Loveland, G A, Pietersz, I F, McKenzie   +3 more
openaire   +2 more sources

Mucin-1-related T cell infiltration in colorectal carcinoma

Cancer Immunology, Immunotherapy, 1996
Mucins (MUC) are highly glycosylated molecules widely expressed on epithelia of different origins, including colonic mucosa. Altered glycosylation processes in tumour cells result in the exposure of normally cryptic peptide epitopes, which may then be recognized as tumour-specific antigens.
Mulder, W. M.C., Stukart, M. J., De Windt, E., Wagstaff, J., Scheper, R. J., Bloemena, E.   +5 more
openaire   +4 more sources

Intestinal mucin is a chaperone of multivalent copper

Cell, 2022
Deborah Fass, Tal Ilani
exaly  

Identification of Allobaculum mucolyticum as a novel human intestinal mucin degrader

Gut Microbes, 2021
Guus Van Muijlwijk, Guido Van Mierlo, Noah Palm   +2 more
exaly  

Mucin-1

2018
openaire   +2 more sources

The role of MUC2 mucin in intestinal homeostasis and the impact of dietary components on MUC2 expression

International Journal of Biological Macromolecules, 2020
Meiyi Zhang, Jianxin Zhao
exaly  

The effects of diet and gut microbiota on the regulation of intestinal mucin glycosylation

Carbohydrate Polymers, 2021
Meiyi Zhang, Fengwei Tian, Gang Wang
exaly  

Mucin-1 Staining Method

2020
openaire   +1 more source