Results 171 to 180 of about 164,299 (302)

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

Epilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza, Greta Volpedo, Antonella Riva, Pasquale Striano, Annamaria Vezzani   +4 more
wiley   +1 more source

Meibomian Gland-Mediated Drug Delivery via Eyelid Application of Troxipide Nanoparticles Improves an N-Acetylcysteine-Induced Dry Eye. [PDF]

Pharmaceutics
Otake H, Tanaka R, Ogata F, Misra M, Kanai K, Tsubaki M, Yamamoto N, Kawasaki N, Nagai N.   +8 more
europepmc   +1 more source

The gut microbiome and drug‐resistant epilepsy: Microbiome–antiseizure medication interactions and implications for pharmacoresistance

Epilepsia Open, EarlyView.
Abstract Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy and represents a major unmet clinical need. While traditional hypotheses of pharmacoresistance have focused on alterations in drug targets, efflux transporter overexpression, and intrinsic disease severity, the gut microbiome has recently emerged as a ...
Khaled Zammar, Majd A. AbuAlrob, Musab Ali, Simona Lattanzi, Boulenouar Mesraoua   +4 more
wiley   +1 more source

Exploring the Adhesion Potential of <i>Bifidobacterium bifidum</i> Strains Isolated from Infant Feces. [PDF]

Foods
Wu Y, Xiao L, Ding S, He M, Shao H, Zhao T, Zhang L, Zhang S.   +7 more
europepmc   +1 more source

Probiotic Spore Inspired Oral Drug Delivery System With Multiple‐Barriers‐Crossing Ability Modulates Gut‐Brain Axis for Parkinson's Disease Therapy

Exploration, EarlyView.
Inspired by the germination of probiotic spores, we utilize the excellent characteristics of spores to break through multiple barriers of oral brain‐targeted delivery. Besides the probiotics mediated gut‐brain communication, the spore coat proteins derived nanosystems with multiple‐barriers‐crossing ability alleviate neurodegeneration.
Qianhua Feng, Yuying Mei, Jia Zhang, Liying Sun, Bingqian Si, Huimin Zhou, Huifang Xiao, Runhan Liu, Jieyun Zhang, Lei Wang   +9 more
wiley   +1 more source

Invasive mucinous adenocarcinoma of the lung: integrating molecular landscape, imaging phenotypes, and translational therapeutic strategies. [PDF]

Transl Lung Cancer Res
Wang Z, Wang J, Liu S, Zong S, Wang X.
europepmc   +1 more source

Fabrication of a salt‐containing coacervated emulsion: Application in low‐salt mayonnaise with enhanced saltiness perception

Food Biomacromolecules, EarlyView.
Salt‐containing whey protein‐chitosan coacervates enabled stable emulsions with controlled sodium distribution, thereby enhancing perceived saltiness in low‐salt mayonnaise. Improved microstructure, rheology, and stability promoted sodium release during oral processing, offering an effective strategy for sodium reduction without compromising sensory ...
Mingfeng Wu, Xiaoyin Li, Xiaoshan Tang, Yucong Zou, Yang Yuan   +4 more
wiley   +1 more source

A qPCR-based approach targeting the microbial gene marker <i>nanA</i> of mucin-degrading <i>Akkermansia</i> in Parkinson's disease. [PDF]

J Parkinsons Dis
Mizutani Y, Fujii T, Maeda Y, Funasaka K, Ohno E, Hirooka Y, Watanabe H, Tochio T.   +7 more
europepmc   +1 more source

Beyond Gut Modulation: A Critical Review of the Therapeutic Potential, Safety, and Clinical Prospects of Natural Polysaccharides for IBD

Food Safety and Health, EarlyView.
In this review, we critically summarized the application of natural polysaccharides (NPs) for the treatment of IBD. This approach combines, in a unique way (right), the basic structure–activity relationships of NPs from different origins (left) with their multipronged mode of action, which involves modulation of the gut microbiota and other ...
Felix Danso, A. M. Abd El‐Aty, Kwaku Amoah, Xianghong Ju   +3 more
wiley   +1 more source

Selective Utility of Periodic Acid-Schiff Staining in Sinonasal Masses: A Cross-Sectional Observational Study. [PDF]

Cureus
Toppo EM, Mahto SK, Banerjee S, Jamaiyar A, Paswan MK, Kumar A.   +5 more
europepmc   +1 more source