Results 61 to 70 of about 29,433 (206)

Optical Detection of Cellular Signals at Material Interfaces

Advanced Healthcare Materials, EarlyView.
Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren, Jitong Ren, Zixin Zhang, Koney Eungkon Kim, Francis L. Hong, Yuecheng Peter Zhou   +5 more
wiley   +1 more source

Mucins and calcium phosphate precipitates additively stimulate cholesterol crystallization

Journal of Lipid Research, 1998
Human biliary mucin and calcium binding protein (CBP) influence formation of both calcium salt precipitates and cholesterol crystals and colocalize in the center of cholesterol gallstones.
A.A. van den Berg, J.D. van Buul, G.N.J. Tytgat, A.K. Groen, J.D. Ostrow   +4 more
doaj   +1 more source

Collagen‐Based Gut‐on‐Chip for In Vitro Modeling of Intestinal Barrier Function and Host‐Pathogen Interactions

Advanced Materials Technologies, EarlyView.
A collagen‐based gut‐on‐chip model replicates the intestinal extracellular matrix, supporting villi‐like structures, tight junctions, and mucin production. This biomimetic platform enables rapid epithelial differentiation and functional barrier formation.
Fernanda López García, Jacques Leng, Hugo de Oliveira, Pierre Nassoy, Karine Dementhon   +4 more
wiley   +1 more source

Gastric remnant carcinoma : histochemical and immunohistochemical profile [PDF]

, 2004
Includes bibliographical references (leaves 52-65).Gastric remnant carcinoma (GRC) is a gastric cancer that develops in gastric remnant more than five years after resection for benign disease. GRC comprises 1 %-9% of all gastric cancers.
Elazzabi, Tawfik
core   +1 more source

TRAIP Mediates Alcohol‐Induced Liver Injury through Regulating β‐catenin Ubiquitin Degradation via Direct Interaction

Advanced Science, EarlyView.
This study reveals that NF‐κB1‐driven TRAIP upregulation in ALD correlates with disease severity. Mechanistically, TRAIP directly binds β‐catenin via its CC domain and promotes its K48‐linked ubiquitination and degradation, which is independent of the GSK3β/β‐TrCP pathway.
Zhan Wu, Mingjiang Liu, Lijuan Liao, Zhaohong Mo, Wenli Xu, Linfeng Mao, Yubing Chen, Qiuli Xie, Ming Yao, Shilian Chen, Stephen Tomlinson, Sebastian Mueller, Songqing He, Guandou Yuan   +13 more
wiley   +1 more source

Targeted Restoration of the Microbial Tryptophan Oxidative Pathway Ameliorates Autism‐Like Behavioral and Synaptic Deficits

Advanced Science, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo, Caian He, Xiao Xiao, Jingmeng Li, Zilong Zhang, Ying He, Chuanchuan Wang, Jiale Zhao, Jun Gong, Jiarui Liang, Tian Yuan, Haiting Sun, Xuebo Liu, Chao Gao, Zhigang Liu   +14 more
wiley   +1 more source

Electrochemical Characterization of Protein Adsorption onto YNGRT-Au and VLGXE-Au Surfaces

Sensors, 2015
The adsorption of the proteins CD13, mucin and bovine serum albumin on VLGXE-Au and YNGRT-Au interfaces was monitored by electrochemical impedance spectroscopy in the presence of [Fe(CN)6]3−/4−.
Hanna Trzeciakiewicz, Jose Esteves-Villanueva, Rania Soudy, Kamaljit Kaur, Sanela Martic-Milne   +4 more
doaj   +1 more source

Membrane-Tethered Mucin-like Polypeptides Sterically Inhibit Binding and Slow Fusion Kinetics of Influenza A Virus [PDF]

, 2019
The mechanism(s) by which cell-tethered mucins modulate infection by Influenza A viruses (IAVs) remains an open question. Mucins form both a protective barrier that can block virus binding and recruit IAVs to bind cells via the sialic ...
Corleone, Delaveris, Elizabeth, Webster, Carolyn, Bertozzi, Steven, Boxer, Steven, Banik   +4 more
core   +1 more source

Single‐Cell Transcriptomic Analysis of Tumor Heterogeneity and the Microenvironment in Pseudomyxoma Peritonei

Advanced Science, EarlyView.
This study presents a single‐cell atlas of pseudomyxoma peritonei spanning primary and paired metastatic lesions. Distinct epithelial substates, stromal remodeling, immune exclusion, lipid metabolic reprogramming, and a candidate angiogenic network were identified in metastatic lesions.
Xi Li, Lei Wang, Lei Ai, Zimeng Li, Zhaochangci Chen, Yuchen Luo, Tianran Zhang, Mengjia Liao, Songhao Wang, Jiajia Cui, Ke Liu, Chengxian Guo, Guodong Liu, Jiye Yin, Wei Wu   +14 more
wiley   +1 more source

The Genome of Akkermansia muciniphila, a Dedicated Intestinal Mucin Degrader, and Its Use in Exploring Intestinal Metagenomes [PDF]

, 2011
Background: The human gastrointestinal tract contains a complex community of microbes, fulfilling important health-promoting functions. However, this vast complexity of species hampers the assignment of responsible organisms to these functions. Recently,
Willem M de Vos, Kant Ravi, van Passel, Mark W. J., Mark Van Passel, Zoetendal, Erwin G., Chain, Patrick S. G., de Vos Willem M., Chain Patrick S. G., van Passel Mark W. J., Hauke Smidt, Derrien Muriel, Patrick S G Chain, Derrien, Muriel, Airi Palva, Palva Airi, Derrien, M.M.N., Malfatti, Stephanie A., Woyke, Tanja, Malfatti, S.A., Mark W J van Passel, Caroline M Plugge, Ravi Kant, Tanja Woyke, Kant, R., Muriel Derrien, Smidt, Hauke, Erwin G Zoetendal, Willem M. De Vos, Vos, W.M., de, Smidt, H., Malfatti Stephanie A., Mark W. J. Van Passel, Erwin G. Zoetendal, Plugge Caroline M., Plugge, Caroline M., de Vos, Willem M., Zoetendal, E.G., Stephanie A. Malfatti, Patrick S. G. Chain, Palva, Airi, Smidt Hauke, Plugge, C.M., Caroline M. Plugge, Passel, M.W.J., van, Kant, Ravi, Woyke Tanja, Stephanie A Malfatti, Zoetendal Erwin G., Palva, A.   +48 more
core   +1 more source