Characterization of the Adherence of Clostridium difficile Spores: The Integrity of the Outermost Layer Affects Adherence Properties of Spores of the Epidemic Strain R20291 to Components of the Intestinal Mucosa [PDF]
, 2016 Indexación: Web of Science.Clostridium difficile is the causative agent of the most frequently reported nosocomial diarrhea worldwide. The high incidence of recurrent infection is the main clinical challenge of C. difficile infections (CBI). Formation of
Banawas, Saeed +9 more
core +2 more sources
Mucosubstances in the porcine gastrointestinal tract: Fixation, staining and quantification [PDF]
, 2019 Mucins are of great interest in intestinal research and histochemical methods are often employed to identify them. Since it is in the nature of mucins that they are “hard to hold onto” once they come into contact with water, a frequently used medium in ...
Drewes, Barbara +3 more
core +1 more source
A mucin-like peptide from Fasciola hepatica instructs dendritic cells with parasite specific Th1-polarizing activity [PDF]
, 2017 Fasciolosis is a trematode zoonosis of interest in public health and cattle production. We report here the immunostimulatory effect of a 66 mer mucin-like peptide from Fasciola hepatica (Fhmuc), which synergizes with lipopolysaccharide (LPS) to promote ...
Brossard, Natalie +6 more
core +1 more source
Effect of native gastric mucus on in vivo hybridization therapies directed at Helicobacter pylori [PDF]
, 2015 Helicobacter pylori infects more than 50% of the worldwide population. It is mostly found deep in the gastric mucus lining of the stomach, being a major cause of peptic ulcers and gastric adenocarcinoma. To face the increasing resistance of H.
Azevedo, Nuno F +13 more
core +6 more sources
Micromanagement in the gut : microenvironmental factors govern colon mucosal biofilm structure and functionality [PDF]
, 2015 The human gut microbiome provides us with functional features that we did not have to evolve ourselves and can be viewed as a structured microbial community that operates like a microbial organ within the human host.
De Weirdt, Rosemarie, Van de Wiele, Tom
core +2 more sources
Advances in the Evaluation of Gastrointestinal Absorption Considering the Mucus Layer
Pharmaceutics, 2023 Because of the increasing sophistication of formulation technology and the increasing polymerization of compounds directed toward undruggable drug targets, the influence of the mucus layer on gastrointestinal drug absorption has received renewed ...
Kaori Miyazaki +2 more
doaj +1 more source
Formulation and evaluation of floating mucoadhesive alginate beads for targetingHelicobacter pylori [PDF]
, 2015 Objectives: There are various obstacles in the eradication of Helicobacter.pylori (H. pylori) infections, including low antibiotic levels and poor accessibility of the drug at the site of the infection.
Adebisi +59 more
core +1 more source
FEBS Open Bio, 2018 Mucin glycoproteins play an important role in protecting the gut epithelium by keeping gut microbes from direct contact with the gut epithelium while allowing for diffusion of small molecules from the lumen to the epithelium.
Sercan Karav +2 more
doaj +1 more source
Arabinoxylans, inulin and Lactobacillus reuteri 1063 repress the adherent-invasive Escherichia coli from mucus in a musosa-comprising gut model [PDF]
, 2016 The microbiota that colonises the intestinal mucus may particularly affect human health given its proximity to the epithelium. For instance, the presence of the adherent-invasive Escherichia coli (AIEC) in this mucosal microbiota has been correlated with
De Weirdt, Rosemarie +6 more
core +2 more sources
Steroidal but not embryonic regulation of mucin 1 expression in bovine endometrium
The Journal of Reproduction and Development, 2021 In cow herd management, inadequate embryo implantation leads to pregnancy loss and causes severe economic losses. Thus, it is crucial to understand the molecular mechanisms underlying endometrial receptivity and subsequent embryo implantation ...
Kaiyu KUBOTA +4 more
doaj +1 more source