Results 161 to 170 of about 109,953 (344)

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

BMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen, Ying Yao, Yan Zhang, Xinyu Shi, Ling Bai, Yang Zhong, Yan Zhang, Kun Zhang   +7 more
wiley   +1 more source

Combating cancer immunotherapy resistance: a nano‐medicine perspective

Cancer Communications, EarlyView.
Abstract Cancer immunotherapy offers renewed hope for treating this disease. However, cancer cells possess inherent mechanisms that enable them to circumvent each stage of the immune cycle, thereby evading anti‐cancer immunity and leading to resistance.
Xiangyi Kong, Xintong Xie, Juan Wu, Xiangyu Wang, Wenxiang Zhang, Shuowen Wang, Daria Valerievna Abbasova, Yi Fang, Hongnan Jiang, Jidong Gao, Jing Wang   +10 more
wiley   +1 more source

Lipid metabolism reprograming by SREBP1‐PCSK9 targeting sensitizes pancreatic cancer to immunochemotherapy

Cancer Communications, EarlyView.
Abstract Background Pancreatic cancer's aberrant lipid metabolism fuels cell growth, invasion, and metastasis, yet its impact on immune surveillance and immunotherapy is unclear. This study investigated how sterol regulatory element‐binding transcription factor 1 (SREBP1)‐driven lipid metabolism affects the tumor microenvironment (TME) in pancreatic ...
Mengyi Lao, Xiaozhen Zhang, Zejun Li, Kang Sun, Hanshen Yang, Sicheng Wang, Lihong He, Yan Chen, Hanjia Zhang, Jiatao Shi, Daqian Xu, Tingbo Liang, Xueli Bai   +12 more
wiley   +1 more source

Neoplasia papilar intraductal mucinosa de páncreas Intraductal papillary mucinous carcinoma of the pancreas

Revista Colombiana de Cirugía, 2008
La neoplasia papilar intraductal de páncreas es una entidad poco frecuente, raramente invasiva, de bajo potencial de malignización, de presentación poco típica y, generalmente, asintomática, que afecta la cola o el cuerpo pancreático y en muchas ...
Héctor López, Emilio Moreno, María Teresa García, Íngrid Álvarez   +3 more
doaj  

Evaluation of the 2015 AGA guidelines on pancreatic cystic neoplasms in a large surgically confirmed multicenter cohort [PDF]

, 2017
Early, Dayna S, et al.,, Gaddam, Srinivas, Kushnir, Vladimir M, Mullady, Daniel   +4 more
core   +2 more sources

NAT10 regulates tumor progression and immune microenvironment in pancreatic ductal adenocarcinoma via the N4‐acetylated LAMB3‐mediated FAK/ERK pathway

Cancer Communications, EarlyView.
Abstract Background N‐acetyltransferase 10 (NAT10) was reported to be associated with the immune microenvironment in several cancers. However, it is not known in pancreatic ductal adenocarcinoma (PDAC). This study aimed to elucidate the roles and mechanisms of NAT10 in tumor malignancy and the tumor microenvironment (TME) in PDAC.
Enhong Chen, Qin Wang, Leisheng Wang, Zebo Huang, Dongjie Yang, Changyong Zhao, Wuqiang Chen, Shuo Zhang, Shuming Xiong, Youzhao He, Yong Mao, Hao Hu   +11 more
wiley   +1 more source

A case of mucinous carcinoma of the gallbladder with resectable peritoneal recurrence after central bisegmentectomy of the liver.

, 1987
Satoshi Kondo, Yuji Nimura, Naokazu Hayakawa, Hiroshi Hasegawa, Katsushi OKAMOTO, Junichi Kamiya, Hiroshi YAMASE, Shigehiko Shionoya, Kojiro OHTSUKA   +8 more
openalex   +2 more sources

Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review

Chemistry &Biodiversity, EarlyView.
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves, Giulia Cristina de Andreoli Souza, Alvaro Jose Hernandez Tasco, Marcos José Salvador   +3 more
wiley   +1 more source

Radical exenteration surgery is curative in locally advance mucinous prostatic adenocarcinoma involving bladder and rectum

Journal of Surgical Case Reports, 2010
The management of mucinous prostatic adenocarcinoma include hormonal treatment, radiotherapy and radical prostatectomy with variable long-term outcome.
Vincent S W Koo, Mark F Saxby, Naing N K Lynn   +2 more
doaj  

Balancing Antigen Loading on Gold Nanoparticles: Implications for Future Cancer Vaccine Strategies

Chemistry – A European Journal, EarlyView.
The synthesis of multicomponent cancer vaccines on AuNP carriers could be rationalized by the simultaneous functionalization of the antigen and immunomodulator components on the same particles. Immunization with a “diluted” amount of MUC1‐functionalized AuNPs is still capable of eliciting a strong immune response.
Mattia Ghirardello, Ana Guerreiro, Carmen Bretón, Ismael Compañón, Julio Zabalza, Vincenzo Mangini, Jesús M. Peregrina, Gonçalo J. L. Bernardes, Francisco Corzana   +8 more
wiley   +1 more source