Results 151 to 160 of about 56,983 (285)

Logic‐Gated HSV‐TK/GCV Suicide Gene Circuit for Triple‐Negative Breast Cancer

open access: yesAdvanced Science, Volume 13, Issue 20, 9 April 2026.
The BRAS comprises two modular genetic components driven by distinct tumor‐specific promoters and a failsafe layer with the NOT gate. This multi‐input logic gate circuit enables precise, specific expression of HSV‐TK in breast cancer cells with hardly expression in normal cell and effectively inhibits tumor growth in a triple‐negative breast cancer ...
Shasha Tang   +10 more
wiley   +1 more source

Anatomic Diagram as a Novel Assessment Strategy for Subclinical Local Residual Disease in Sinonasal Squamous Cell Carcinoma and Intestinal‐Type Adenocarcinoma

open access: yesInternational Forum of Allergy &Rhinology, Volume 16, Issue 4, Page 333-344, April 2026.
ABSTRACT Objective In the last two decades, transnasal endoscopic surgery (TES) has become pivotal in the management of sinonasal tumors. This approach involves a multiblock tumor resection, adding complexity to the interpretation of surgical margins after pathological examination.
Piergiorgio Gaudioso   +14 more
wiley   +1 more source

Dermatopathological Findings of an Erythema Multiforme‐Like Drug Eruption During Enfortumab Vedotin Plus Pembrolizumab Therapy for Metastatic Urothelial Carcinoma: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT The combination therapy of enfortumab vedotin and pembrolizumab (EV+Pem) is effective for metastatic urothelial carcinoma. However, the dermatopathological findings for treatment‐related adverse events, particularly skin disorders, often remain unclear.
Ryunosuke Murofushi   +7 more
wiley   +1 more source

Cerebellar Cystic Metastasis—An Unusual Presentation of Prostate Adenocarcinoma Dissemination: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Although prostate cancer is among the most common malignant tumors in men, brain metastases from prostatic cancer are infrequent. Brain dissemination is especially rare with the most frequent histological type of prostatic adenocarcinoma. We present a case of a cystic‐hemorrhagic cerebellar metastasis with a solid enhancing component in a ...
Mia Smoljan Basuga   +5 more
wiley   +1 more source

Perianal Paget's Disease: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Perianal Paget's disease is rare and may be secondary to an underlying anorectal adenocarcinoma. Full‐thickness biopsy with immunohistochemistry is key to distinguish primary from secondary disease and to guide staging. Wide local excision is standard, while radiotherapy is a reasonable option when radical surgery is declined.
Daniela Lira   +5 more
wiley   +1 more source

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