Results 131 to 140 of about 199,448 (274)

The Power of MUC2 in Mucinous Adenocarcinomas

Pathobiology
<p>Background: In cancers, key prognostic determinants such as clinical stage and mutational load are well recognized. However, mucinous adenocarcinomas (MACs) display distinct biological behavior as a large proportion of their tumor volume consists of extracellular mucin, predominantly the MUC2 protein, rather than neoplastic cells.
openaire   +3 more sources

Comprehensive and reproducible grading of the Updated Sydney System in gastric biopsies using artificial intelligence: multi‐pathologist validation and a reader study

Histopathology, EarlyView.
SydneyMTL is an interpretable multi‐task model providing four‐level grading for the five Sydney System attributes. By significantly improving diagnostic concordance and reducing reading time, it offers a robust clinical tool to alleviate pathologist workloads and standardize routine gastric biopsy screening.
Ho Heon Kim, Won Chan Jeong, Yuri Hwang, Gisu Hwang, Kyungeun Kim, Young Sin Ko   +5 more
wiley   +1 more source

mpMRI features of mucinous prostate cancer: two case reports

The Egyptian Journal of Radiology and Nuclear Medicine
Background Mucinous adenocarcinoma of the prostate (MACP) is one of the rarest variants of prostatic neoplasm, with more aggressive behavior than non-mucinous prostatic cancer.
Giuseppe Chiacchio, Alessandro Grimaldi, Edoardo Beatrici, Riccardo Rossi, Simone Cappuccelli, Lucia Pitoni, Vito Lacetera, Giuliana Gabrielloni, Alberto Rebonato, Simone Scarcella, Valerio Beatrici   +10 more
doaj   +1 more source

Primary vs. Metastatic Mucinous Adenocarcinoma of the Skin: a Case Report and Discussion of Immunohistochemical Techniques

, 2011
Paper presented to the 7th Annual Symposium on Graduate Research and Scholarly Projects (GRASP) held at the Marcus Welcome Center, Wichita State University, May 4, 2011.Research completed at the Department of Physician AssistantBackground: Primary ...
Schettle, Lidia S.
core  

Efficacy of Endoscopic Ultrasound‐guided Fine Needle Biopsy With Simplified Macroscopic On‐site Evaluation (With Video)

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Background and Aims With advances in preoperative chemotherapy and comprehensive genomic profiling, endoscopic ultrasound‐guided fine needle biopsy (EUS‐FNB) has become vital for diagnosing pancreatic and peridigestive tract lesions. However, evidence remains limited regarding the performance of new‐generation puncture needles and simplified ...
Kento Shionoya, Ryosuke Tonozuka, Shuntaro Mukai, Yuki Joyama, Takayoshi Tsuchiya, Reina Tanaka, Kenjiro Yamamoto, Kazumasa Nagai, Yukitoshi Matsunami, Hiroyuki Kojima, Hirohito Minami, Noriyuki Hirakawa, Kyoko Asano, Takao Itoi   +13 more
wiley   +1 more source

Worst Histology‐Based Risk Stratification for Lymph Node Metastasis in Patients With T1b Colorectal Cancer: A Retrospective Pathology‐based Study

DEN Open, Volume 7, Issue 1, April 2027.
This study evaluates a pathology‐based refinement of lymph node metastasis risk stratification in pT1b colorectal cancer. Compared with the conventional dominant histologybased assessment, a worst histologybased approach focused on poorly differentiated adenocarcinoma, combined with submucosal invasion depth and lymphatic invasion, more effectively ...
Satomi Shibata, Shin‐ichiro Horiguchi, Koichi Koizumi, Daichi Sadato, Ryoko Shimizuguchi, Akinari Takao, Jun Nakahodo, Yawara Kubota, Itaru Kubota, Hiroki Kato, Misato Takao, Daisuke Nakano, Kazushige Kawai, Tatsuro Yamaguchi, Tsunekazu Hishima, Toshiro Iizuka   +15 more
wiley   +1 more source

Adverse Pathological Features and Worse Prognosis in Rectal Cancer Compared With Colon Cancer in T1 and T2 Stages

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Background and Aim Emerging endoscopic techniques are expanding opportunities for minimally invasive therapy in early colorectal cancers (CRCs). Data regarding the clinicopathological features and outcomes of colon versus rectal cancers in Tis, T1, and T2 stages remain limited.
Shunto Iwasaki, Shin‐ei Kudo, Yuta Kouyama, Katsuro Ichimasa, Shigenori Semba, Yuriko Morita, Yuki Takashina, Tomotaka Takizawa, Yu Nimura, Taishi Okumura, Kenta Nakahara, Yasuharu Maeda, Noriyuki Ogata, Takemasa Hayashi, Naruhiko Sawada, Toshiyuki Baba, Tetsuo Nemoto, Masashi Misawa   +17 more
wiley   +1 more source

Clinical Utility and Safety of a Novel Ultraslim Catheter‐Type Peroral Cholangioscope/Pancreatoscope: A Single‐Center Case Series

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Peroral cholangioscopy (POCS) and peroral pancreatoscopy (POPS) enable direct intraductal visualization for pancreatobiliary disease diagnosis and management. Nonetheless, conventional devices have relatively large diameters, limiting their use in narrow ducts.
Hiroyuki Kojima, Shuntaro Mukai, Atsushi Sofuni, Takayoshi Tsuchiya, Reina Tanaka, Ryosuke Tonozuka, Kazumasa Nagai, Yukitoshi Matsunami, Hirohito Minami, Noriyuki Hirakawa, Kyoko Asano, Kento Shionoya, Kazuki Hama, Takao Itoi   +13 more
wiley   +1 more source

Early Gastric Cancer Detected During 15‐year Surveillance After Ménétrier Disease Remission and Successfully Treated With Endoscopic Submucosal Dissection: A Case Report

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Ménétrier disease (MD) was diagnosed based on hypoalbuminemia and giant gastric folds extending from the body to the fundus in a woman in her 70s. A serum anti‐Helicobacter pylori antibody test and urea breath test yielded negative results.
Takaaki Shamoto, Hideko Yamamoto, Takehito Naito, Masahiro Yamada, Hirotaka Suzuki, Emiko Hida, Takafumi Yamamoto, Yoshifumi Arai, Hiroshi Matsubara   +8 more
wiley   +1 more source

Immune Markers and Risk of Pancreatic Cancer in the European EPIC Cohort

International Journal of Cancer, Volume 159, Issue 9, Page 2146-2157, 1 November 2026.
The immune system has been implicated as a major driver in pancreatic cancer etiology. Previous cohort studies have found associations between pancreatic cancer and single immune system‐derived markers, but omics‐based evidence remains scarce. In this prospective case–control study, the authors investigated 92 proteins involved in immune reactions and ...
Verena A. Katzke, Yue Chen, Srimanti Dutta, Federico Canzian, Julie Louise Munk Andersen, Agnetha Linn Rostgaard‐Hansen, Léa Bouteille, Vinciane Rebours, Thérèse Truong, Matthias B. Schulze, Benedetta Bendinelli, Valeria Pala, Vittorio Simeon, Rosario Tumino, Carlotta Sacerdote, Roel Vermeulen, P. Martijn Kolijn, Sjoerd G. Elias, Marta Crous‐Bou, Maria‐José Sánchez, Ana Jimenez‐Zabala, José María Huerta, Marcela Guevara, Nick Wareham, Marie Breeur, Mattias Johansson, James Yarmolinsky, Daniele Campa, Rudolf Kaaks   +28 more
wiley   +1 more source