Results 111 to 120 of about 176,444 (236)

Morphology‐Based Cytosponge Cytology Versus Concurrent Endoscopic Biopsy for Detecting Dysplasia in Barrett's Oesophagus Surveillance: A Prospective, Single‐Centre Paired Study

Cytopathology, EarlyView.
In this prospective single‐centre study, morphology‐based Cytosponge cytology detected Barrett's dysplasia with high specificity (92.6%) and positive predictive value (86.7%) against concurrent biopsy. Cytosponge cytology may help prioritize endoscopic surveillance, but reporting requires specific training and its sensitivity may improve with ...
Vincent Labador, Cherry Galorport, Hamid Masoudi, Robert Enns, Eric Lam, Neal Shahidi, Pam Wong, Wei Xiong   +7 more
wiley   +1 more source

Challenging Cytologic Diagnosis of Intrahepatic Cholangiocarcinoma Arising in Ductal Plate Malformation

Cytopathology, EarlyView.
This case describes a rare intrahepatic cholangiocarcinoma arising in a background of ductal plate malformation/Von Meyenburg complex. Predominant sampling of benign ductal proliferations obscured a focal malignant component, highlighting the importance of recognizing subtle cytomorphologic atypia, correlating pathologic findings with imaging, and ...
Jeffrey Z. Lin, Andrew C. Gordon, Xiaoqi Lin, Lawrence J. Jennings, Lucy Jager   +4 more
wiley   +1 more source

Extracellular fluid viscosity influences the mechanics and migration of MDA‐MB‐231 cells in a macromolecule‐dependent manner

The FEBS Journal, EarlyView.
Macromolecule‐dependent increases in extracellular fluid viscosity alter cell phenotype. These distinct macromolecules create different extracellular environments that modulate cell morphology and mechanoprotein expression, migration and invasion capacity, and cellular mechanical properties.
Ian M. Smith, Nikka Givpoor, Chenchen Handler, Ariel Abraham, Shohini Banerjee, Giuliano Scarcelli, Kimberly M. Stroka   +6 more
wiley   +1 more source

Additional file 1 of Limited resection is comparable to lobectomy for tumor size ≤ 2 cm pulmonary invasive mucinous adenocarcinoma

Supplementary Figure 1: Distribution of Histologic Subtypes of Invasive Mucinous ...
Chang Chen (30907), Tingting Wang (123983), Xuefei Hu (1785751), Yuming Zhu (9025007), Weikang Lin (18448769), Hang Su (324726), Huikang Xie (6599114), Long Wang (95893), Long Xu (218743), Deping Zhao (6185654), Gening Jiang (431928), Haifeng Wang (188956), Dong Xie (16842)   +12 more
core   +1 more source

Appendiceal mucinous adenocarcinoma invading the ovaries with subsequent pseudomyxoma peritonei: a histopathological case report

Archive of Clinical Medicine
Introduction. Appendiceal mucinous adenocarcinoma (AMA) is a rare gastrointestinal malignancy that may spread beyond the appendix, invading adjacent organs and leading to pseudomyxoma peritonei (PMP).
Olha Shulepa, Yaroslava Shulepa, Viktoria Bedei, Taras Kotyk   +3 more
doaj   +1 more source

CD36‐mediated lipid rewiring in the metabolic adaptation of tumour ecosystems

The FEBS Journal, EarlyView.
Nutrient deprivation drives a lipid‐centric shift in tumour metabolic symbiosis and signalling network. CD36 functions as a bidirectional bridge, transferring fatty acids from stromal donors (adipocytes, CAFs) to the ecosystem tumour‐ and microenvironment‐dependently.
Anna Sebestyén, Viktória Varga, Fatime Szalai, Risa Miyaura, Nóra Förhécz, Bálint Csikós, Rebeka Gelencsér, Zsófia Gábriel, Timea Komlódi, Katalin Dezső, Ildikó Krencz, Dorottya Moldvai   +11 more
wiley   +1 more source

Bringing Gene Therapy Into Real World Clinical Practice

Haemophilia, EarlyView.
ABSTRACT Introduction Adeno‐associated virus (AAV)‐based gene therapy for haemophilia has shifted therapeutic paradigms by enabling hepatic gene transfer, restoring endogenous clotting factor expression, and reducing reliance on conventional prophylactic treatments. Two products, valoctocogene roxaparvovec (haemophilia A) and etranacogene dezaparvovec (
Wolfgang Miesbach, Pratima Chowdary, Margareth C. Ozelo   +2 more
wiley   +1 more source

Comparative study of imaging and pathology of primary mucinous adenocarcinoma with different imaging manifestations

The Clinical Respiratory Journal
Background Pulmonary mucinous adenocarcinoma is a special type of lung cancer. Its imaging manifestations are diverse, which brings challenges to clinical diagnosis. However, its formation mechanism is unclear. Objective The objective of this study is to
Jun Han, Jie Gao, Demei Chen, Mou Du, Yuxin Wu, Xidong Ma, Mei Xie, Hua Han, Chongchong Wu, Xinying Xue   +9 more
doaj   +1 more source

Traditional serrated adenoma of the colorectum: Evolving concepts in histological classification and terminology

Histopathology, EarlyView.
The definition of the colorectal traditional serrated adenoma (TSA) has evolved to recognize a broader morphological spectrum, including classical, flat and mixed lesions reflecting early development and neoplastic progression. Updated WHO classification highlights the need for consistent terminology to improve recognition and to distinguish TSA from ...
Christophe Rosty, Maurice B. Loughrey, Taiki Hashimoto, Markus Mäkinen, Rish K. Pai, Shigeki Sekine, Rhonda K. Yantiss, Iris D. Nagtegaal   +7 more
wiley   +1 more source

Orcein is a more sensitive stain than EVG for detecting large vessel (venous) invasion in colorectal cancer

Histopathology, EarlyView.
Orcein is more sensitive than EVG for detecting intramural and extramural large vessel (venous) invasion than EVG and H&E in colorectal cancer. Background Large vessel invasion (VI) is a well‐established adverse prognostic factor in colorectal cancer (CRC).
Timothy Law, Won‐Tak Choi, Sarah E. Umetsu, Kwun Wah Wen   +3 more
wiley   +1 more source