Results 191 to 200 of about 370,037 (337)

Temporal trends in incidence and mortality of colorectal cancer in Denmark from 2007 to 2022

open access: yesInternational Journal of Cancer, Volume 157, Issue 4, Page 634-643, 15 August 2025.
What's new? Colorectal cancer (CRC) is the third most common cancer in the Western world. Widespread use of screening programs has helped raise awareness of the disease and improve survival rates. To make sure screening, treatment, research, and education goals stay relevant, it is important to collect accurate population‐based estimates of CRC ...
Ida Ravnsbæk Johannsen   +3 more
wiley   +1 more source

Colorectal Carcinoma in Childhood and Adolescence: Microsatellite Instability Correlates With a Favorable Prognosis

open access: yesPediatric Blood &Cancer, Volume 72, Issue 8, August 2025.
ABSTRACT Background Colorectal cancer (CRC) accounts for 10% of cancer cases worldwide; however, pediatric CRC is extremely rare, with an annual incidence of one to two cases per million. Microsatellite instability (MSI) has been shown to play a relevant prognostic role in adult CRC. Corresponding data for pediatric CRC are lacking. This study examines
Hannah Wild   +14 more
wiley   +1 more source

Influence of a nationwide colorectal cancer screening program on the incidence of synchronous colorectal peritoneal metastases

open access: yesInternational Journal of Cancer, Volume 157, Issue 2, Page 232-238, 15 July 2025.
What's new? Colorectal cancer screening has been shown to decrease the incidence of the disease and allow detection at an earlier stage. Here, the authors also show that, since the introduction of the colorectal cancer screening program in the Netherlands in 2014, the incidence of synchronous peritoneal metastases in colorectal cancer patients has ...
Laskarina J. K. Galanos   +5 more
wiley   +1 more source

Human sporadic breast carcinoma histotypes driven by the Human Betaretrovirus homologous to Mouse Mammary Tumor Virus

open access: yesInternational Journal of Cancer, Volume 157, Issue 2, Page 371-383, 15 July 2025.
What's new? While estrogens, obesity, and alcohol are recognized risk factors for breast cancer, a viral hypothesis has been suggested based on the murine model of Mouse Mammary Tumor Virus (MMTV)‐induced mammary tumors. This study analyzed sequences of the human homolog of MMTV across human breast carcinoma histotypes, detecting the virus in all types
Prospero Civita   +12 more
wiley   +1 more source

A quantitative tumor‐wide analysis of morphological heterogeneity of colorectal adenocarcinoma

open access: yesThe Journal of Pathology: Clinical Research, Volume 11, Issue 4, July 2025.
Abstract The intertumoral and intratumoral heterogeneity of colorectal adenocarcinoma (CRC) at the morphologic level is poorly understood. Previously, we identified morphological patterns associated with CRC molecular subtypes and their distinct molecular motifs. Here we aimed to evaluate the heterogeneity of these patterns across CRC.
Mihnea P Dragomir   +7 more
wiley   +1 more source

Small Intestine on a Chip Demonstrates Physiologic Mucus Secretion in the Presence of Lacticaseibacillus rhamnosus Biofilm

open access: yesBiotechnology and Bioengineering, Volume 122, Issue 7, Page 1816-1827, July 2025.
Dash and coworkers have fabricated a small intestine on a chip, which encapsulates the physiology and biofilm of the small intestinal epithelium. The dynamic system showed villus differentiation within 5 days of flow, and the mucus layer and biofilm showed small intestinal characteristics.
Sanat Kumar Dash   +2 more
wiley   +1 more source

A Case Series and Literature Review of Angiosarcoma With Malignant Effusion—A Challenging Cytologic Diagnosis With Dire Prognostic Implications

open access: yesDiagnostic Cytopathology, Volume 53, Issue 7, Page E119-E126, July 2025.
ABSTRACT Angiosarcoma with malignant effusion is an uncommon yet clinically aggressive presentation, which poses as a diagnostic pitfall with its overlapping cytomorphologic features with metastatic adenocarcinoma. In this article, two cases reported in the literature were reviewed for cytology, immunocytochemistry, and clinical course.
Jamie C. Y. Lam   +3 more
wiley   +1 more source

The Interplay of Cross‐Organ Immune Regulation in Inflammation and Cancer

open access: yesMedComm, Volume 6, Issue 7, July 2025.
Organs interact dynamically through immune regulation, influencing systemic immune responses and disease progression. We review molecular and cellular mechanisms of cross‐organ immune regulation in inflammation and cancer, focusing on gut, liver, and brain interactions with other organs.
Jie Dou   +6 more
wiley   +1 more source

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