Organoids From Mucinous Appendiceal Adenocarcinomas as High-Fidelity Models for Individual Therapy
BackgroundMucinous appendiceal adenocarcinoma (MAA) is a rare, heterogeneous disease. Patients with unrespectable mucinous appendiceal adenocarcinoma presenting with peritoneal spread are treated by intraperitoneal chemotherapy, hyperthermic ...
Guangyao Liu+14 more
doaj +1 more source
A deep learning model for gastric diffuse-type adenocarcinoma classification in whole slide images [PDF]
Gastric diffuse-type adenocarcinoma represents a disproportionately high percentage of cases of gastric cancers occurring in the young, and its relative incidence seems to be on the rise. Usually it affects the body of the stomach, and presents shorter duration and worse prognosis compared with the differentiated (intestinal) type adenocarcinoma.
arxiv
A Polymerase-chain-reaction Assay for the Specific Identification of Transcripts Encoded by Individual Carcinoembryonic Antigen (CEA)-gene-family Members [PDF]
Carcinoembryonic antigen (CEA) is a tumor marker that belongs to a family of closely related molecules with variable expression patterns. We have developed sets of oligonucleotide primers for the specific amplification of transcripts from individual CEA ...
Ang+34 more
core +1 more source
Mucinous Carcinoma of the Skin: A Case Report
Primary mucinous carcinoma of the skin is a rare malignant neoplasm showing predilection to the periorbital region. These tumours are indolent and low-grade, with a tendency for local, sometimes multiple, recurrences.
Adarsh Kumar Jhunjhunwala+7 more
doaj +1 more source
A Bioinformatics Study for Recognition of Hub Genes and Pathways in Pancreatic Ductal Adenocarcinoma [PDF]
Background: The aim of this study is to use bioinformatics to discover the biomarkers associated with patients with Pancreatic Ductal Adenocarcinoma(PDAC). Material and Methods: GSE28735, GSE15471, and GSE62452 are gene microarray datasets drived from the GEO database, included 153 PDAC samples and 145 normal samples. By analyzing both Gene Ontology (
arxiv
A33 shows similar sensitivity to but is more specific than CDX2 as an immunomarker of colorectal carcinoma [PDF]
Aims: CDX2 is widely used as a sensitive and specific immunomarker for colorectal carcinoma (CRC) but neither this sensitivity nor specificity is absolute. This study is the first known comparison of CDX1 and A33 against CDX2 as immunomarkers for CRC.
Adamczyk, Lukasz A.+5 more
core +1 more source
Calcified mucinous adenocarcinoma of the stomach metastatic to the iris: a case report
Background Gastric cancer has a wide spectrum of clinical features, imaging manifestations, and pathology. Punctate calcifications in gastric cancer are infrequent but are usually found in mucinous adenocarcinoma.
Miki Kaneko+18 more
doaj +1 more source
Systematic assessment of HER2/neu in gynecologic neoplasms, an institutional experience. [PDF]
BackgroundHER2/neu overexpression and/or amplification has been widely studied in a number of solid tumors, primarily in the breast. In gynecologic neoplasms, determination of HER2/neu status has not been well studied as a predictive biomarker in anti ...
Apple, Sophia K+5 more
core +2 more sources
Pancreatic tumors imaging: an update [PDF]
Currently, ultrasound (US), computed tomography (CT) and Magnetic Resonance imaging (MRI) represent the mainstay in the evaluation of pancreatic solid and cystic tumors affecting pancreas in 80-85% and 10-15% of the cases respectively. Integration of US,
Baccari, Paolo+8 more
core +1 more source
MicroRNAs targeting oncogenes are down-regulated in pancreatic malignant transformation from benign tumors [PDF]
BACKGROUND MicroRNA (miRNA) expression profiles have been described in pancreatic ductal adenocarcinoma (PDAC), but these have not been compared with pre-malignant pancreatic tumors.
A Cimmino+93 more
core +4 more sources