Results 51 to 60 of about 199,448 (274)

Organoids From Mucinous Appendiceal Adenocarcinomas as High-Fidelity Models for Individual Therapy

Frontiers in Medicine, 2022
BackgroundMucinous appendiceal adenocarcinoma (MAA) is a rare, heterogeneous disease. Patients with unrespectable mucinous appendiceal adenocarcinoma presenting with peritoneal spread are treated by intraperitoneal chemotherapy, hyperthermic ...
Guangyao Liu, Xing Xiao, Yujian Xia, Weibing Huang, Wei Chen, Jiannan Xu, Songyao Chen, Huijin Wang, Jitao Wei, Huan Li, Man Shu, Xiaofang Lu, Changhua Zhang, Yulong He, Yulong He   +14 more
doaj   +1 more source

Nanomaterial Strategies for Pulmonary Delivery of Immunotherapeutics in Lung Cancer Treatment

Advanced Healthcare Materials, EarlyView.
Inhalable immunotherapeutic nanomedicines enable organ‐selective immune modulation by overcoming pulmonary delivery barriers and concentrating therapy within lung tumors. This Review defines how nanomaterial properties govern airway deposition, retention, cellular partitioning, and immune activation across vaccines, checkpoint blockade, STING agonists,
Han Zhang, Wei Tang
wiley   +1 more source

An Analysis of Clinicopathological Outcomes and the Utility of Preoperative MRI for Patients Undergoing Resection of Mucinous and Non-Mucinous Colorectal Cancer Liver Metastases

Frontiers in Oncology, 2022
Background and AimsMucinous colorectal cancer has traditionally been associated with high rates of recurrence and poor long-term survival. There is limited published data on outcomes for patients undergoing liver resection for metastatic mucinous ...
Ian S. Reynolds, Ian S. Reynolds, Paul M. Cromwell, Éanna J. Ryan, Erinn McGrath, Rory Kennelly, Ronan Ryan, Niall Swan, Kieran Sheahan, Des C. Winter, Emir Hoti   +10 more
doaj   +1 more source

Primary Cutaneous Low Grade Mucinous Adenocarcinoma of Eyelid [PDF]

, 2010
Primary cutaneous mucinous adenocarcinoma is a rare adnexal neoplasm, eyelid being the most common site of presentation. Clinically it is mistaken for a benign / cystic lesion.
S, Vijayshankar, Abhishek MG, U, Geethalakshmi, Indira CS, MG, Abhishek, Vijayshankar S, Geethalakshmi U, CS, Indira   +7 more
core  

Mucinous adenocarcinoma of the appendix with inguinal node metastases [PDF]

, 2021
Mucinous adenocarcinoma of the appendix is a rare neoplasm with a low propensity for lymph node metastasis. The present case refers to an appendicular mucinous adenocarcinoma with inguinal lymph node metastasis.
Fernandes, Urânia, Rita Marques, Monteiro, Ana, João Pinto-de-Sousa, Urânia Fernandes, Vaz-Pereira, Ricardo, Ricardo Vaz-Pereira, Marques, Rita, Pinto-de-Sousa, João, Ana Monteiro   +9 more
core   +1 more source

Collagen‐Based Gut‐on‐Chip for In Vitro Modeling of Intestinal Barrier Function and Host‐Pathogen Interactions

Advanced Materials Technologies, EarlyView.
A collagen‐based gut‐on‐chip model replicates the intestinal extracellular matrix, supporting villi‐like structures, tight junctions, and mucin production. This biomimetic platform enables rapid epithelial differentiation and functional barrier formation.
Fernanda López García, Jacques Leng, Hugo de Oliveira, Pierre Nassoy, Karine Dementhon   +4 more
wiley   +1 more source

A minor (<50%) signet-ring cell component associated with poor prognosis in colorectal cancer patients: a 26-year retrospective study in China.

PLoS ONE, 2015
BackgroundWe performed a retrospective study to determine the cancer-specific survival of colorectal cancer patients with a component of signet-ring cells or mucin comprising < 50% of the tumor mass.MethodsA total of 2454 patients seen in our hospital ...
Yinuo Tan, Jianfei Fu, Xiaofen Li, Jiao Yang, Mengjie Jiang, Kefeng Ding, Jinghong Xu, Jun Li, Ying Yuan   +8 more
doaj   +1 more source

Role of colectomy in the management of appendiceal tumors: a retrospective cohort study

BMC Gastroenterology, 2023
Background Appendiceal tumors represent a range of histologies that vary in behavior. Recommendations for treatment with appendectomy versus right hemicolectomy (RHC) for different tumor types are evolving and sometimes conflicting.
Victoria A. Marks, Daniel Kerekes, Samuel Butensky, Nita Ahuja, Caroline Johnson, Kiran Turaga, Sajid A. Khan   +6 more
doaj   +1 more source

Single‐Cell Transcriptomic Analysis of Tumor Heterogeneity and the Microenvironment in Pseudomyxoma Peritonei

Advanced Science, EarlyView.
This study presents a single‐cell atlas of pseudomyxoma peritonei spanning primary and paired metastatic lesions. Distinct epithelial substates, stromal remodeling, immune exclusion, lipid metabolic reprogramming, and a candidate angiogenic network were identified in metastatic lesions.
Xi Li, Lei Wang, Lei Ai, Zimeng Li, Zhaochangci Chen, Yuchen Luo, Tianran Zhang, Mengjia Liao, Songhao Wang, Jiajia Cui, Ke Liu, Chengxian Guo, Guodong Liu, Jiye Yin, Wei Wu   +14 more
wiley   +1 more source

Insulin-like growth factor-1 receptor inhibition overcomes gefitinib resistance in mucinous lung adenocarcinoma.: IGF1R inhibition in mucinous lung adenocarcinoma

, 2011
International audienceThe appropriate selection of patients is a major challenge in the treatment of non-small cell lung cancer (NSCLC) with epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs).
Tenaud, Corine, de Fraipont, Florence, Martine Antoine, Jacques Cadranel, Cadranel, Jacques, Wislez, Marie, Benoît Busser, Denis Moro-Sibilot, Dufort, Sandrine, Hurbin, Amandine, Moro-Sibilot, Denis, Marie Wislez, Rabbe, Nathalie, Jean-Luc Coll, Sandrine Dufort, Amandine Hurbin, Corine Tenaud, Florence de Fraipont, Busser, Benoît, Nathalie Rabbe, Antoine, Martine, Coll, Jean-Luc, Brambilla, Elisabeth, Elisabeth Brambilla   +23 more
core   +1 more source