Results 61 to 70 of about 199,448 (274)

Targeting GALNT7 Disrupts the TAZ O‐GalNAcylation Feedback Loop to Suppress Gallbladder Cancer Progression

Advanced Science, EarlyView.
Aberrant GALNT7‐mediated O‐GalNAcylation stabilizes TAZ to drive gallbladder cancer progression through a feed‐forward transcriptional loop. Structure‐based screening identifies Olaparib as a potent GALNT7 antagonist that disrupts this oncogenic axis, providing an immediate therapeutic strategy for this aggressive malignancy.
Peng Qiu, Ming Zhang, Yunxiang Feng, Yibo Deng, Kai Zhao, Xiangyu Li, Yun Lu, Li Tian, Tao Yang, Wei Yao, Jianming Wang, Zhengdong Deng   +11 more
wiley   +1 more source

Calcified mucinous adenocarcinoma of the stomach metastatic to the iris: a case report

Journal of Medical Case Reports, 2019
Background Gastric cancer has a wide spectrum of clinical features, imaging manifestations, and pathology. Punctate calcifications in gastric cancer are infrequent but are usually found in mucinous adenocarcinoma.
Miki Kaneko, Tadashi Namisaki, Hiroaki Takaya, Hitoshi Mori, Mitsuteru Kitade, Yasushi Okura, Kenichiro Seki, Shinya Sato, Keisuke Nakanishi, Koh Kitagawa, Takahiro Ozutsumi, Naotaka Shimozato, Kosuke Kaji, Tomoyuki Otani, Tokiko Nakai, Chiho Obayashi, Akira Mitoro, Junichi Yamao, Hitoshi Yoshiji   +18 more
doaj   +1 more source

Impact of Postoperative Infectious Complications on Long‐Term Survival After Curative Resection for Colorectal Cancer: A Multicenter Study in the Minimally Invasive Era

Annals of Gastroenterological Surgery, EarlyView.
Postoperative infectious complications (PICs) have been associated with poor long‐term outcomes after colorectal cancer surgery, but evidence in the modern minimally invasive era remains limited. In this multicenter cohort of 5377 patients undergoing curative resection, PICs were independently associated with worse overall survival and relapse‐free ...
Takehito Yamamoto, Ryosuke Mizuno, Yoshiro Itatani, Tetsuya Shiota, Masahiro Yamada, Tadayoshi Yamaura, Mami Yoshitomi, Kazutaka Obama   +7 more
wiley   +1 more source

Mucinous Carcinoma of the Skin: A Case Report

Journal of Nepal Medical Association, 2022
Primary mucinous carcinoma of the skin is a rare malignant neoplasm showing predilection to the periorbital region. These tumours are indolent and low-grade, with a tendency for local, sometimes multiple, recurrences.
Adarsh Kumar Jhunjhunwala, Dilasma Gharti Magar, Dipesh Upreti, Niku Thapa, Arnab Ghosh, Sushma Thapa, Sudeep Regmi, Bishowdeep Timilsina   +7 more
doaj   +1 more source

Biological Resectability in Colorectal Liver Metastases: A Nomogram‐Based Continuous Risk Model to Define Borderline Disease

Annals of Gastroenterological Surgery, EarlyView.
KRAS mutation demonstrated a prognostic impact according to primary tumor sidedness, independent of tumor morphology, in patients undergoing hepatectomy for colorectal liver metastases. A nomogram integrating biological and clinicopathological factors was developed to provide continuous biological risk assessment.
Yuzo Umeda, Toshiharu Mitsuhashi, Tomokazu Fuji, Toru Kojima, Takeshi Koujima, Tatsuo Matsuda, Daisuke Satoh, Masaru Inagaki, Kosei Takagi, Toshiyoshi Fujiwara   +9 more
wiley   +1 more source

Impact of extended insurance coverage on survival outcomes among patients with metastatic colorectal cancer in Taiwan

British Journal of Clinical Pharmacology, EarlyView.
Aims Predetermined treatment duration limits (PTDLs) are often used by Taiwan's National Health Insurance Administration to contain healthcare costs, but they may compromise patient outcomes. Therefore, we studied Taiwan's 2017 extension of the bevacizumab PTDL from 24 to 36 weeks in metastatic colorectal cancer (mCRC) to evaluate whether prolonged ...
Wei‐Ming Huang, Chen‐Han Chueh, Chien‐Yu Tseng, Christopher N. Kaufmann, Earl J. Morris, Chiao‐En Wu, Yi‐Wen Tsai   +6 more
wiley   +1 more source

Recidiva pélvica do adenocarcinoma retal. [PDF]

, 1998
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Departamento de Clínica Médica, Curso de Medicina, Florianópolis ...
Gomes, André de Miranda
core  

Mucinous adenocarcinoma arising in an anorectal fistula

, 2008
Mucinous adenocarcinoma in association with chronic anal fistula is a rare case in clinical practice. The aim of this article was to report a rare case of anal gland mucinous adenocarcinoma in a patient who was treated in the Hospital of Kaunas ...
Linas Venclauskas, Dainius Pavalkis, Darius Pranys, Žilvinas Saladžinskas, Algimantas Tamelis   +4 more
core   +1 more source

Association Between Socioeconomic Position and Diagnosis, Treatment and Survival of Patients With Stage I–III Rectal Cancer in the Netherlands

International Journal of Cancer, EarlyView.
ABSTRACT Socioeconomic position (SEP) influences cancer care and outcomes, even in countries with government‐funded healthcare. This population‐based study examined associations between SEP, rectal cancer care and survival of patients in the Netherlands.
Suzanne E. N. de Vries, Felice N. van Erning, Mieke J. Aarts, Alice M. Couwenberg, Laskarina J. K. Galanos, Irene E. G. van Hellemond, Ignace H. J. T. de Hingh, Robin Lurvink, Iris D. Nagtegaal, Johannes H. W. de Wilt, Marloes A. G. Elferink   +10 more
wiley   +1 more source

Mucocele of the appendix: An unusual cause of lower abdominal pain in a patient with ulcerative colitis [PDF]

, 2005
The authors report the case of a 60-year-old male patient. In November 2001 he developed intestinal symptoms of bloody diarrhea and abdominal pain. Colononoscopy and biopsy established the diagnosis of ulcerative colitis (proctosigmoiditis).
Győri, Gabriella, Papp, János, Lakatos, Péter László, Fuszek, Péter, Járay, Balázs, Lukovich, Péter, Halász, Judit, Lakatos, László   +7 more
core   +1 more source