Results 81 to 90 of about 382,234 (365)

Gene signature driving invasive mucinous adenocarcinoma of the lung

EMBO Molecular Medicine, 2017
Though invasive mucinous adenocarcinoma of the lung (IMA) is pathologically distinctive, the molecular mechanism driving IMA is not well understood, which hampers efforts to identify therapeutic targets.
M. Guo, K. Tomoshige, M. Meister, T. Muley, T. Fukazawa, T. Tsuchiya, Rebekah A. Karns, A. Warth, I. Fink-Baldauf, T. Nagayasu, Y. Naomoto, Yan Xu, M. Mall, Yutaka Maeda   +13 more
semanticscholar   +1 more source

Zinc‐Coordinated Trienzyme Nanogel Cascade Therapy for Accelerated Post‐Pancreatectomy Cutaneous Wound Healing

Advanced Materials, EarlyView.
A zinc‐coordinated nanogel assembly is reported that co‐delivers three enzymes to regulate glucose, oxidative stress, and oxygen levels. This system mimics natural enzyme cascades to reprogram the wound environment after pancreatectomy. In a post‐pancreatectomy mouse model, it accelerates healing by reducing infection, promoting blood vessel growth ...
Yedong Ma, Chengke Xie, Chengyu Liao, Binting Huang, Siqi Liu, Junhua Kong, Xiaotong Fan, Zibiao Li, Shi Chen, Chaobin He   +9 more
wiley   +1 more source

Giant mucinous adenocarcinoma of the appendix: a case report

Journal of Medical Case Reports, 2017
Background Appendiceal mucinous adenocarcinoma is an extremely rare disease in clinical practice. Here, we report a case of unprecedented size that occupied the entire abdomen of a man.
Sheng-Chun Dang, Ming-Ming Sun, Lu-Lu Liu, Abdul Malik, Jian-Xin Zhang, Yi-Yi Fan, Song Zou, Lei Cui, Jian-Guo Qu, Ji-Xiang Chen   +9 more
doaj   +1 more source

Mucinous Adenocarcinoma and Carcinoid Tumor Arising Within an Ovarian Mature Cystic Teratoma: A Case Report

Oman Medical Journal, 2023
The coexistence of both mucinous adenocarcinoma and carcinoid tumor within an ovarian mature cystic teratoma is extremely rare. We report a case of an 18-year-old Omani woman with a left ovarian cyst.
Sara Al Harthi, Moza Al Kalabni, Badriya Al Qassabi, Radiya Al Ajmi   +3 more
doaj   +1 more source

Data mining of gene arrays for biomarkers of survival in ovarian cancer [PDF]

, 2015
The expected five-year survival rate from a stage III ovarian cancer diagnosis is a mere 22%; this applies to the 7000 new cases diagnosed yearly in the UK.
Ball, GR, Boocock, DJ, Coveney, C, Deen, S, Rees, RC   +4 more
core   +2 more sources

Unraveling the Role of MDK‐SDC4 Interaction in Pancreatic Cancer‐Associated New‐Onset Diabetes by Single‐Cell Transcriptomic Analysis

Advanced Science, EarlyView.
Midkine (MDK) is a mediator of the interaction between pancreatic cancer and beta cells. MDK, which originated from pancreatic ductal adenocarcinoma cells, exerted deleterious effects on paraneoplastic beta cells by binding to the SDC4 receptor on the beta cell surface and subsequently downregulating the Ras signaling pathway, thereby impairing insulin
Zengyu Feng, Jianyao Lou, Chuanshuai Lin, Haocheng Yu, Yuheng Tu, Jiali Gong, Xiawei Li, Yulian Wu   +7 more
wiley   +1 more source

Primary Pulmonary Mucinous (Colloid) Adenocarcinoma that Arose in the Cavernomyoplasty Area in a Patient with Tuberculosis: A Rare Case Report [PDF]

Türk Patoloji Dergisi, 2017
Primary pulmonary mucinous (colloid) adenocarcinoma is a rare type of lung cancer. Its arising in the cavernomyoplasty area has not been reported before.
Neşe A. YENER, Nesrin SARIMAN, Mehmet M. ATASOY, Ahmet MİDİ, Alpay ÖRKİ   +4 more
doaj   +1 more source

MicroRNAs targeting oncogenes are down-regulated in pancreatic malignant transformation from benign tumors [PDF]

, 2012
BACKGROUND MicroRNA (miRNA) expression profiles have been described in pancreatic ductal adenocarcinoma (PDAC), but these have not been compared with pre-malignant pancreatic tumors.
A Cimmino, A Grimson, A Keller, A Lal, A Singh, Adam E. Frampton, AE Szafranska, AE Szafranska, AL Warshaw, AM Bellizzi, AM Krichevsky, AN Bartley, Andreas Keller, BM Bolstad, C Almoguera, C Galanis, C Mayr, C Stefano, D Bartsch, D Bonci, DS Klimstra, DV Sahani, F Takeshita, FA Sinicrope, G Garcea, GA Calin, Georgios Giamas, GK Smyth, GK Smyth, H Matthaei, H Wang, J Lu, J Meister, J Torrisani, J Yu, Jimmy Jacob, Jonathan Krell, JS Desgrosellier, JS Oh, Justin Stebbing, K Izeradjene, K Ohuchida, K Satoh, K Yoshizawa, KC Miranda, L Castellano, L Xia, Leandro Castellano, Long R. Jiao, Loredana Pellegrino, M Bloomston, M Crawford, M Dillhoff, M Fabbri, M Goggins, M Seux, M Tanaka, Marc Tjwa, MC du Rieu, N Abe, N Habbe, Nagy A. Habib, Nicole Tsim, O Basturk, OA Kent, Panagiotis Vlavianos, Patrizia Cohen, R Bhattacharya, R Feng, Raida Ahmad, RI Aqeilan, S Griffiths-Jones, S Griffiths-Jones, S Hamada, S Mukherjee, S Reddy, S Vorwerk, S Watanabe, S Yu, SD Selcuklu, SF Tavazoie, SM Johnson, SYG Friedlander, T Ishikawa, T Paranjape, WA Mardin, WG Zhao, WR Brugge, X Chen, X Li, Y Akao, Y Benjamini, Y Hochberg, YJ Chua   +93 more
core   +4 more sources

Nrf2 Drives Epigenetic Reprogramming and Acts as the Master Regulator of KLF4 Expression and Activity in Arsenic‐Induced Transformation

Advanced Science, EarlyView.
Nrf2 isn't just a protector—it's a driver of cancer stemness. The study uncovers how arsenic‐activated Nrf2 directly upregulates KLF4, a key pluripotency factor, fueling oncogenic reprogramming. Through enhancer activation and self‐reinforcing loop, Nrf2 and KLF4 co‐opt gene networks linked to epithelial‐to‐mesenchymal transition and tumor growth ...
Ziwei Wang, Zhuoyue Bi, Jessica Bamrah, Yiran Qiu, Wenxuan Zhang, Bandar Saeed Almutairy, Haoyan Ji, John D. Haley, Chitra Thakur, Fei Chen   +9 more
wiley   +1 more source

Phenotypic and Genotypic Appraisal of Pulmonary Mucinous Adenocarcinoma: A Retrospective Study

National Journal of Laboratory Medicine, 2023
Introduction: Lung cancer is the second most common cancer diagnosed in the world. According to GLOBOCAN 2020, it is approximately 11.4% of all malignancies and accounts for one in five cancer deaths worldwide.
VG Deepak Roshan, Ashwini Ramji, M Saravanan, Vipin Gopinath, Sangeetha K Nayanar   +4 more
doaj   +1 more source