Results 181 to 190 of about 67,233 (350)

Mass Spectrometry-Compatible Elution Technique Enables an Improved Mucin-Selective Enrichment Strategy to Probe the Mucinome [PDF]

Keira E. Mahoney, Vincent Chang, Taryn M. Lucas, Krystyna Maruszko, Stacy A. Malaker   +4 more
openalex   +1 more source

Challenges of modeling pristane‐induced lupus in non‐human primates

Animal Models and Experimental Medicine, EarlyView.
Systemic lupus erythematosus (SLE) in cynomolgus monkeys was modeled by two intraperitoneal injections of pristane at a dose of 3.5 mL/kg, administered at weeks 1 and 23. Serum samples from all monkeys that received pristane tested positive for antinuclear antibodies.
Elena Vladimirovna Vinogradova, Maria Alexandrovna Varavko, Yakov Yuryevich Ustyugov, Alexey Alexandrovich Aleksandrov, Dmitry Alexandrovich Khochenkov, Yulia Nikolaevna Linkova   +5 more
wiley   +1 more source

Combinatorial targeting of G‐protein‐coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug‐induced liver injury

Hepatology, EarlyView., 2022
CHIN117 is a dual cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist and G‐protein‐coupled bile acid receptor 1 (GPBAR1) agonist. In the liver, GPBAR1 and CYSLTR1 are coexpressed by liver sinusoidal endothelial cells (LSECs), HSCs, circulating monocytes/macrophages, and liver resident macrophages (Kupffer cells).
Michele Biagioli, Silvia Marchianò, Cristina di Giorgio, Rosalinda Roselli, Martina Bordoni, Rachele Bellini, Bianca Fiorillo, Valentina Sepe, Bruno Catalanotti, Chiara Cassiano, Maria Chiara Monti, Eleonora Distrutti, Angela Zampella, Stefano Fiorucci   +13 more
wiley   +1 more source

The barrier and protective functions of intestinal mucin in defense against <i>Candida albicans</i>. [PDF]

Front Microbiol
Liu Y, Li D, Ma L, Wen Y, Shi D.
europepmc   +1 more source

Mucin Glycoprotein Nanoparticles Enable a Selective Antisense Therapy for Oncogenic MicroRNAs

Advanced NanoBiomed Research, EarlyView.
Mucin glycoproteins are turned into nanoparticles by employing synthetic DNA strands, which have a dual function: they stabilize the nanoparticles and act as binding sites for intracellular miRNA‐21. Thus, upon internalization into tumor cells, these mucin nanoparticles can deplete miRNA‐21 from the cytosol, which induces apoptosis in vitro and in vivo.
Ceren Kimna, Thomas Mayer, Di Zhang, Matthias Marczynski, Carolin A. Rickert, Fabio Henkel, Lennart J. K. Weiss, Friedrich C. Simmel, Yuxia Luan, Oliver Lieleg   +9 more
wiley   +1 more source

IPEC-J2 as a cellular model for studying intestinal mucus. [PDF]

Sci Rep
Dessauge F, Vincent A, Trefeu C, Mayeur-Nickel F, Wiart-Letort S, Macierzanka A, Beaumont M, Grundy MM.   +7 more
europepmc   +1 more source

Higher levels of neutrophil extracellular traps in mucoid middle ear effusion obtained from otitis media with effusion in children. [PDF]

Ann Med
Guo L, Li T, Duan Q, Duan Y, Liu W, Ma N, Liu S, Wang X, Zhang S, Tian E, Ni X, Zhang J.   +11 more
europepmc   +1 more source

Spectrum of Mucin-producing Neoplastic Conditions of the Abdomen and Pelvis: Evaluation with Cross-sectional Imaging

, 2011
Hyuk Moo Kwon
openalex   +1 more source

Toxocara canis mucins among other excretory-secretory antigens induce in vitro secretion of cytokines by mouse splenocytes [PDF]

, 2015
Ewa Długosz, Katarzyna Wasyl, M. Klockiewicz, Marcin Wiśniewski   +3 more
openalex   +1 more source

Exploring the Muco-Microbiotic Interface as a Hub for Microbial Metabolites and Immune Regulation in Gastroenteric Health and Disease. [PDF]

Cells
Carista A, Gratie MI, Tornatore E, Accomando S, Tomasello G, Picone D, Burgio S, Cappello F.   +7 more
europepmc   +1 more source