Results 71 to 80 of about 67,233 (350)

Mucus and Mucins: The Underappreciated Host Defence System

Frontiers in Cellular and Infection Microbiology, 2022
The mucosal surfaces that form the boundary between the external environment and the underlying tissue are protected by a mucus barrier. Mucin glycoproteins, both secreted and cell surface mucins, are the major components of the barrier. They can exclude
Yong Hua Sheng, Sumaira Z. Hasnain, Sumaira Z. Hasnain   +2 more
doaj   +1 more source

Evaluating Cytocompatibility of Corynebacterium glutamicum‐poly Vinyl Alcohol Living Biomaterials for Ocular Use

Advanced Healthcare Materials, EarlyView.
In ophthalmology, living biomaterials such as living contact lenses appear promising for sustained drug delivery or biosensing. The cytocompatibility of Cg‐PVA hydrogels, developed as a model living contact lens, is investigated with the ocular surface, showing their potential translation to the clinic.
Krupansh Desai, Lorely Garcia‐Sanchez, Maryam Amini, Lara Luana Teruel‐Enrico, Silke Siegrist, Aránzazu del Campo, Sara Trujillo   +6 more
wiley   +1 more source

Therapeutic Effect of Human Adipose Tissue-Derived Mesenchymal Stem Cells in Experimental Corneal Failure Due to Limbal Stem Cell Niche Damage [PDF]

, 2017
Producción CientíficaLimbal stem cells are responsible for the continuous renewal of the corneal epithelium. The destruction or dysfunction of these stem cells or their niche induces limbal stem cell deficiency (LSCD) leading to visual loss, chronic pain,
Calonge Cano, Margarita, Galindo de la Rosa, Sara, Herreras Cantalapiedra, José María, López Paniagua, Marina, Mata Sampedro, Ana de la, Nieto Miguel, Teresa, Plata Cordero, María, Rey, Esther   +7 more
core   +2 more sources

Mucin expression patterns in histological grades of colonic cancers in Ghanaian population

The Pan African Medical Journal, 2017
INTRODUCTION: Myriad roles of mucins in normal tissues have been well documented, including lubrication of the epithelial surfaces; protection from physical damage; facilitation in cell-cell signaling and suppression of inflammatory activity ...
Kwabena Owusu Danquah, Ernest Adjei, Solomon Quayson, Ernest Adankwah, Daniel Gyamfi, Paul Poku Sampene Ossei, Gideon Dzikunu, Portia Mensah, Cecilia Lepkor   +8 more
doaj   +1 more source

Evaluating the Antiviral Efficacy of Encapsulated PKC Inhibitor BIM‐I against influenza A Virus Infection

Advanced Healthcare Materials, EarlyView.
This study explores nanoparticle delivery of the protein kinase C inhibitor bisindolylmaleimide‐I (BIM‐I) to combat influenza A virus infections. Encapsulation in biodegradable PLGA nanoparticles improved safety while maintaining the compound's strong antiviral activity.
Laura Klement, Jana Ismail, Josefine Schroeder, Amod Godbole, Johanna Schreiber, Christine Weber, Zoltan Cseresnyes, Marc T. Figge, Bettina Löffler, Ulrich S. Schubert, Stephanie Schubert, Christina Ehrhardt, Carsten Hoffmann   +12 more
wiley   +1 more source

Drop spreading and drifting on a spatially heterogeneous film: capturing variability with asymptotics and emulation [PDF]

, 2018
A liquid drop spreading over a thin heterogeneous precursor film (such as an inhaled droplet on the mucus-lined wall of a lung airway) will experience perturbations in shape and location as its advancing contact line encounters regions of low or high ...
Coveney, Sam, Jensen, Oliver E., Xu, Feng   +2 more
core   +2 more sources

Ferritin‐Doped Nanoparticles Triggered Tumor‐Specific Darkening for Enhanced Photothermal Tumor Ablation and Immune Activation

Advanced Healthcare Materials, EarlyView.
Ferritin‐doped hybrid nanoparticles triggered accurate tumor‐specific hemorrhage for enhanced in situ photothermal therapy and evoked anti‐tumor immunity. Notably, HFn/GA‐Fe specifically induced tumor hemorrhage 12 h after intravenous injection, resulting in visible color darkening. Through photoacoustic imaging, tumor vessels could be clearly observed
Haidong Zha, Xiao Liang, Long Xi, Jiamao Chen, Wenzhao Zhong, Zhen Yuan, Meng Xu, Ying Zheng   +7 more
wiley   +1 more source

Lamellar Structures of MUC2-Rich Mucin: A Potential Role in Governing the Barrier and Lubricating Functions of Intestinal Mucus [PDF]

, 2012
Mucus is a ubiquitous feature of mammalian wet epithelial surfaces, where it lubricates and forms a selective barrier that excludes a range of particulates, including pathogens, while hosting a diverse commensal microflora.
Garcia De La Torre, Angela, MacIerzanka, Adam, MacKie, Alan R., Mills, Clare, Mills, E. N Clare, Rigby, Neil M., Round, Andrew N.   +6 more
core   +1 more source

The Roles of Transmembrane Mucins Located on Chromosome 7q22.1 in Colorectal Cancer

Cancer Management and Research, 2021
Hussain Almasmoum Laboratory Medicine Department, Faculty of Applied Medical Science, Umm Al-Qura University, Makkah, 7607, Saudi ArabiaCorrespondence: Hussain AlmasmoumLaboratory Medicine Department, Faculty of Applied Medical Science, Umm Al-Qura ...
Almasmoum H
doaj  

Urachal Mucinous Cystadenocarcinoma [PDF]

BMJ Case Reports, 2019
A 57-year-old man presented with a 6-month history of pelvic fullness. He had no lower urinary tract symptoms or altered bowel habits. On examination, there was a non-tender pelvic mass which extended from the pubic symphysis to the level of the umbilicus.
Ryan Pereira, Stephen McGeorge, Marlon Perera, Ian Vela   +3 more
openaire   +3 more sources